Oxycodone News and Research

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Opioid dependence produces permanent changes in the brains of rats

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction.

24 Jan 2020

Simple computer settings can affect opioid pills prescribed to patients

Simple, no-cost computer changes can affect the number of opioid pills prescribed to patients, according to a new UC San Francisco study.

21 Jan 2020

Most youths do not get timely addiction treatment after opioid overdose

A study of more than 4 million Medicaid claims records during a recent seven-year period concludes that less than a third of the nearly 3,800 U.S. adolescents and young adults who experienced a nonfatal opioid overdose got timely (within 30 days) follow-up addiction treatment to curb or prevent future misuse and reduce the risk of a second overdose.

17 Jan 2020

Family doctors in rural America tackle crisis of addiction and pain

Dr. Angela Gatzke-Plamann didn’t fully grasp her community’s opioid crisis until one desperate patient called on a Friday afternoon in 2016.

10 Jan 2020

FDA’s risk-management program to curb improper opioid prescribing may not have been effective

A risk-management program set up in 2012 by the U.S. Food and Drug Administration to curb improper prescribing of extended-release and long-acting opioids may not have been effective because of shortcomings in the program's design and execution, according to a paper from researchers at the Johns Hopkins Bloomberg School of Public Health.

7 Jan 2020

Addictions and drug interactions common among patients not disclosing their medication history

Some patients skip telling their doctors about the drugs and medications they are consuming. A new study shows that these patients are at a greater risk of unpleasant and sometimes dangerous drug-drug interactions as well as addictions. The study was published in the latest issue of The Journal of the American Osteopathic Association. The study is titled, “Role of opioid-involved drug interactions in chronic pain management”.

11 Dec 2019

Risk of opioid overdose rises after de-addiction treatment completion

A study from Columbia University reveals that patients, who have been successfully treated with buprenorphine for opioid addiction, are at a greater risk of overdose after completion of the treatment. The study was titled, “Acute care, prescription opioid use, and overdose following discontinuation of long-term buprenorphine treatment for opioid use disorder”, and was published in the latest issue of The American Journal of Psychiatry. This study was funded and supported by the National Institute on Drug Abuse (NIDA) and the Agency for Healthcare Research and Quality.

2 Dec 2019

Researchers uncover the binding mechanism of opioid receptor

Together with colleagues from Shanghai, Brussels, Canada and the USA, researchers from the University of Bonn have uncovered the binding mechanism of an important pain receptor.

27 Nov 2019

Urban hotspots of opioid abuse among high-schoolers revealed

A new study from researchers at the Johns Hopkins Bloomberg School of Public Health found that in several cities and counties the proportion of high-schoolers who have ever used heroin or misused prescription opioids is much higher than the national average.

14 Nov 2019

Opioid misuse greatly increases chance of major depressive episode among teen girls

New research by Keith Chan of UAlbany's School of Social Welfare shows that among girls ages 12-17, the misuse of opioids greatly increases the chance of having a major depressive episode. Prescription opioids may include oxycodone, hydrocodone and fentanyl.

1 Nov 2019

GLP-1 receptors could serve as targets for novel medications to treat opioid use disorder

Opioid use disorder and overdose deaths are a major public health crisis in the United States. While medication-assisted treatments for opioid use disorder exist, these treatments remain inadequate for many patients, resulting in a high rate of relapse following detoxification.

31 Oct 2019

Sanford Burnham Prebys scientist receives $3.58 million to advance treatment for opioid-use disorders

The National Institute on Drug Abuse, part of the National Institutes of Health, awarded a $3.58 million grant to Sanford Burnham Prebys scientist Anthony Pinkerton, Ph.D., to advance a potential treatment for opioid-use disorders, called SBI-553.

23 Oct 2019

Unnecessary opioid prescribing after cesarean delivery remains high

Nearly 90% of women who did not use opioids in the hospital after cesarean delivery were nonetheless discharged with a prescription for opioids, according to a study presented at the ANESTHESIOLOGY 2019 annual meeting.

20 Oct 2019

Changes to state law reduce new opioid prescriptions by 22% in Penn Medicine’s New Jersey practices

The total amount of opioids dispensed per new opioid prescription decreased by 22 percent in Penn Medicine outpatient practices in New Jersey after the state passed a law limiting prescriptions to a five-day supply for new opioid prescriptions.

14 Oct 2019

UC Davis engineers develop new test to detect opioid drugs in exhaled breath

A test to detect opioid drugs in exhaled breath has been developed by engineers and physicians at the University of California, Davis. A breath test could be useful in caring for chronic pain patients as well as for checking for illegal drug use.

4 Oct 2019

Longtime crusader against Oxycontin begins to see the fruits of her struggle

In the 15 years since she lost her son to a single OxyContin pill, Barbara Van Rooyan has had but one up-close look at the people representing the company that made it.

17 Sep 2019

Accelerating drug discovery process to help patients

An international research team has developed a new strategy that can predict the potential clinical implications of new therapeutic compounds based on simple cellular responses.

15 Sep 2019

Developing next generation treatment to counteract opioid addiction

There are many moments in the human experience when tragedy elicits not only compassion, but inspiration. When Mike Zhang heard the story of a mother whose son died of an opioid overdose just one month after the teenager's introduction to the drug at a party, the Virginia Tech researcher wanted to help.

11 Sep 2019

Opioids after surgery overly prescribed in USA and Canada

A new study covering several institutions shows that patients recovering from surgery in the US or Canada have a 50% chance of being treated with opioids. This is seven times as high as the corresponding percentage in Sweden. Within the US, the initial dosages are likely to be over 200 morphine milligram equivalents (MME) – much more than in Canada.

5 Sep 2019

In India’s burgeoning pain market, U.S. drugmakers stand to gain

Pain, like death, is a universal phenomenon. The sour grimace on the woman's face, registering her bodily complaints to Dr. G.P. Dureja in his East Delhi office, would be recognized anywhere. Slouched shoulders, pinched forehead. She wore a willowy black kurta and cast a disapproving glance at the five pain physicians-in-training huddled behind Dureja, founder of Delhi Pain Management Centre and one of India's pioneering pain physicians.

28 Aug 2019