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Genetics play a significant role in determining side effects of opiates

Genetics play a significant role in determining which patients will suffer the most from the disturbing side effects of opiates, commonly prescribed painkillers for severe to moderate pain, according to a new Stanford University School of Medicine study, which pinpoints nausea, slowed breathing and potential for addiction as heritable traits.

21 Jun 2012

Roundup: Calpers rate hike approved; Painkiller databases slow abuse in Mass., Minn.; Health workers authorize strike in Philly

The California Public Employees' Retirement System, the third-largest purchaser of health benefits in the country, approved a 9.6 percent increase in health premiums next year for its nearly 1.3 million members.

15 Jun 2012

State roundup: N.Y.'s drug Rx bill passes unanimously, Mass. poll finds Dr. communication essential

New York lawmakers unanimously approved legislation Monday that will require doctors to issue drug prescriptions electronically within three years, meanwhile establishing tighter restrictions on painkillers and other addictive drugs on the state list of controlled substances.

13 Jun 2012

First Edition: June 12, 2012

Today's headlines include news about the pressure health costs are placing on state budgets.

12 Jun 2012

Rapid test to identify patients not responding to painkiller tramadol

French researchers have found a way to identify quickly the 5-10% of patients in whom the commonly used painkiller, tramadol, does not work effectively. A simple blood test can produce a result within a few hours, enabling doctors to switch a non-responding patient on to another painkiller, such as morphine, which will be able to work in these patients.

11 Jun 2012

Simple blood test can quickly identify 'poor metabolisers'

11 Jun 2012

Experts debate whether spinal manipulation for neck pain should be abandoned

The effectiveness of spinal manipulation divides medical opinion. On bmj.com today, experts debate whether spinal manipulation for neck pain should be abandoned.

8 Jun 2012

Drug manufacturers draw attention for politics and pain killers

Politico examines the relationship between industry-group PhRMA and congressional Republicans in the post-health-reform-debate landscape.

11 May 2012

Arthritis rates set to soar

According to new estimates the number of people with arthritis is set to soar with predictions that 1,500,000 Scots will be living with the condition by 2030.

10 May 2012

Viewpoints: Taking aim at 'superbugs'; Friending organ donations; Ariz. and Kansas abortion efforts hurt women

In the battle between humans and infectious bacteria, humans have had the advantage, at least since antibiotics were introduced into our arsenal 70 or so years ago. Now, however, our weapons appear to be turning against us as germs have found ways to outfox antibiotics…. A second challenge is to keep a steady stream of new antibiotics in the pipeline, and this is where the big pharmaceutical companies based in Europe and the U.S. come in….

9 May 2012

Painkillers create quandary for physicians

News outlets report on the hazards -- both in the ER and in maternity wards -- being brought about by painkiller use and abuse.

2 May 2012

Change in attitude may ease chronic pain by aiding sleep: Study

Chronic pain sufferers who learn to dwell less on their ailments may sleep better and experience less day-to-day pain, according to results of research conducted on 214 people with chronic face and jaw pain.

26 Apr 2012

New evidence helps explain additional health benefits of aspirin

New evidence is helping explain additional health benefits of aspirin. Researchers in Canada, Scotland and Australia have discovered that salicylate, the active ingredient in aspirin, directly increases the activity of the protein AMPK (AMP-activated protein kinase), a key player in regulating cell growth and metabolism. AMPK which is considered a cellular fuel-gauge is switched on by exercise and the commonly used anti-diabetic medication metformin.

20 Apr 2012

Two-thirds of adults support single-dose packaging to avoid accidental poisoning

Unintentional poisonings from medicines cause more emergency room visits for young children each year than do car accidents.

17 Apr 2012

Viewpoints: Medicare may be unintended victim of bank crisis; Health care industry's fears of law's reversal

The banks' actions led directly to an increase in government debt, which in turn has made the reduction of that debt by "cutting runaway spending" a centerpiece of the Republican presidential campaign to date.

12 Apr 2012

Viewpoints: An 'easy' SCOTUS case?; Is painkiller addiction really an epidemic?

Nothing in the Supreme Court arguments in the health care case last week, or in the subsequent commentary, has changed my opinion that this is an easy case. It's the court that made it look hard (Linda Greenhouse, 4/4).

7 Apr 2012

Medicaid news: Oregon competitors working together; Calif. 'duals' project launches

A new push to reshape health care in greater Portland is reminiscent, its biggest booster says, of the race to land a man on the moon. Erstwhile health care competitors hope to set aside their differences to care for the region's 200,000 Oregon Health Plan members, says Legacy Health CEO George Brown. The task is happening in a timeline -- Brown snaps his fingers -- "that's like that long. It's a moon shot for sure. What we're trying to do, to my knowledge, has not been attempted any place in the country."

6 Apr 2012

AP: Prescription painkiller sales have 'exploded,' leading experts to fear 'addiction epidemic'

Sales of the nation's two most popular prescription painkillers have exploded in new parts of the country, an Associated Press analysis shows, worrying experts who say the push to relieve patients' suffering is spawning an addiction epidemic.

6 Apr 2012

TLR4/MD-2 protein complex triggers morphine-induced inflammation

A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for improving the efficacy of the widely used painkiller while decreasing its abuse potential.

3 Apr 2012

Long delays for persistent pain management

An article in the Australian Medical Journal reveals that taxpayers are paying $34 billion a year to treat persistent pain. Pain specialist Dr Timothy Semple, and president of the Australian Pain Society, told the Herald Sun chronic back pain, arthritis, nerve injuries and people who needed care after surviving cancer made up significant numbers.

1 Apr 2012