Painkiller News and Research

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Researchers convert β-Pinene into renewable feedstock for sustainable paracetamol and ibuprofen

Researchers have developed scalable processes to convert β-pinene into 4-IPEC, a feedstock for synthesizing sustainable versions of paracetamol and ibuprofen.

19 Jul 2023

Largest clinical case series of laughing gas users finds a predominance of young Asian men

The largest clinical case series to date of recreational users of nitrous oxide, popularly known as laughing gas, has found a predominance of young men of Asian ethnicity among those with neurological side effects who were seen at hospitals in 3 major cities in England.

30 May 2023

Death of a 43-year-old male marks the entry of 'zombie' drug into the UK

The death of a 43-year-old male is the first in the UK to be associated with Xylazine and marks the entry of the drug into the UK drug supply.

26 May 2023

New intervention program can help reduce opioid use for chronic pain

Researchers at the University of Warwick and The James Cook University Hospital, Middlesbrough have led a clinical trial, funded by the National Institute for Health and Care Research (NIHR), on a new treatment which can help people stop needing to use opioid painkillers to manage chronic pain.

23 May 2023

Insomnia drug shows potential as an effective treatment for opioid use disorder

The insomnia drug suvorexant (Belsomra) might be an effective treatment for opioid use disorder, according to a preclinical study from Scripps Research.

27 Apr 2023

Drug-metabolizing enzyme may be a major player in safety concerns related to the painkiller diclofenac

Safety concerns related to the widely used painkiller diclofenac may be tied to a little-studied drug-metabolizing enzyme whose expression can vary as much as 3,000 times from one individual to the next, according to new research.

24 Apr 2023

Researchers compare the action of natural and therapeutic opioids

The human body naturally produces opioid-like substances, such as endorphins, which block the perception of pain and increase the feeling of well-being.

19 Apr 2023

The efficacy of clarithromycin versus levofoxacin-based regimens for H.pylori treatment in naïve patients after the COVID-19 pandemic misuse of antibiotics

Researchers explored the eradication rates of Helicobacter pylori utilizing levofloxacin and clarithromycin-based regimens in patients with prior COVID-19 therapy.

25 Jan 2023

First H5N3 infection in a captive emperor tamarin documented in new study

In a new study, researchers reported the first H5N3 infection in a captive Emperor Tamarin.

19 Dec 2022

Orthopedic surgery patients can recover just as well without using opioid-based painkillers

Patients can recover from orthopedic surgery just as well without using opioid-based painkillers, says a McMaster University and Hamilton Health Sciences (HHS) study published by the Journal of the American Medical Association.

5 Oct 2022

Tiny, touch-based sensor rapidly detects lithium levels from sweat on the surface of a fingertip

Lithium can alleviate the symptoms of bipolar disorder and depression -; if taken in just the right amount.

22 Aug 2022

New biosensor system derived from E. coli bacteria could accelerate drug development

For more affordable, sustainable drug options than we have today, the medication we take to treat high blood pressure, pain or memory loss may one day come from engineered bacteria, cultured in a vat like yogurt.

7 Jul 2022

Skirmishes over medication abortions may renew debate on state vs. federal powers

As the Supreme Court appears poised to overturn Roe v. Wade, the landmark decision that guarantees the constitutional right to an abortion, reproductive rights advocates are considering new ways to protect nationwide access to the procedure.

2 Jun 2022

The new MADD movement: Parents rise up against drug deaths

Life as he knew it ended for Matt Capelouto two days before Christmas in 2019, when he found his 20-year-old daughter, Alexandra, dead in her childhood bedroom in Temecula, California. Rage overtook grief when authorities ruled her death an accident.

23 May 2022

Combination of certain drugs along with ibuprofen can cause acute kidney injury

Anyone who is taking a diuretic and a renin-angiotensin system (RSA) inhibitor for high blood pressure should be cautious about also taking ibuprofen, according to new research.

5 May 2022

A travel nurse leaves fears of hospital drug tampering across three states

Health officials in at least three states are investigating a travel nurse suspected of tampering with and potentially contaminating vials and syringes of opioid painkillers in two hospitals, then returning the vials to medication cabinets where they could be unknowingly given to patients.

14 Apr 2022

Paracetamol use increases blood pressure, study shows

Long-term paracetamol use could increase the risk of heart disease and strokes in people with high blood pressure, a study suggests.

7 Feb 2022

Introducing deuterium makes drugs to have a longer effect

Hydrogen (abbreviated "H") is the lightest of all elements. It usually consists only of a positively charged proton and a negatively charged electron and is also called protium in this form. But there are also two heavier hydrogen isotopes, deuterium and tritium.

24 Dec 2021

Blocking IL-11 signaling can promote liver regeneration after paracetamol-induced damage

Scientists at Duke-NUS Medical School and National Heart Centre Singapore, in collaboration with colleagues in Singapore and the UK, have shown that the human form of the signaling protein interleukin 11 (IL-11) has a damaging effect on human liver cells--overturning a prior hypothesis that it could help livers damaged by paracetamol poisoning.

18 Jun 2021

Surgeons can avoid postoperative opioid prescriptions, studies suggest

Surgeons can ease their patients' pain from common operations without prescribing opioids, and avoid the possibility of starting someone on a path to long-term use, a pair of new studies suggests.

10 Jun 2021