Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Study explores the potential of EZH2 inhibitors GSK126 and Tazemetostat in stimulating β-cell regeneration from pancreatic ductal progenitor cells, offering a novel therapeutic approach for Type 1 Diabetes.

3 Jan 2024

New research project seeks to find innovative treatment pathways for Type 2 diabetes and obesity

A team of Virginia Tech researchers was awarded nearly $2 million from the National Institute of Diabetes and Digestive and Kidney Disease, part of the National Institutes of Health, to explore novel approaches for treating Type 2 diabetes and obesity.

3 Jan 2024

New model links RNA editing glitch to early-stage type 1 diabetes

Hebrew University study proposes a new model suggesting that disrupted RNA editing within pancreatic beta cells might initiate an inflammatory response akin to early-stage type 1 diabetes.

26 Dec 2023

Autopsy study provides new insights into yellow fever's impact on the heart

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.

19 Dec 2023

AGA releases the first comprehensive evidence-based guideline on management of pouchitis

The American Gastroenterological Association (AGA) has released the first comprehensive evidence-based guideline on the management of pouchitis, the most common complication people with ulcerative colitis experience following surgery to remove their colon.

19 Dec 2023

UCL scientists receive £997,000 from the Type 1 Diabetes Grand Challenge

Scientists at the UCL Institute of Immunity & Transplantation (IIT) are part of a team to receive £997,000 from the Type 1 Diabetes Grand Challenge, a new partnership involving The Steve Morgan Foundation, Diabetes UK and JDRF.

19 Dec 2023

Shattering myths: Study reveals new insights on type 1 diabetes and obesity link

Review examines the relationship between type 1 diabetes and weight disorders, debunking myths about T1D and offering recommendations for future research and therapeutic interventions.

18 Dec 2023

Metabolic syndrome linked to higher pancreatic cancer risk, study shows

Study finds a significant association between metabolic syndrome and an increased risk of pancreatic cancer, highlighting the importance of MetS prevention and management.

17 Dec 2023

Epigenetic changes can contribute to the development of type 2 diabetes

Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes.

13 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Study demonstrates that inhibiting stromal class I histone deacetylases (HDACs) can effectively slow down pancreatic cancer progression, shedding light on a new therapeutic approach targeting the tumor microenvironment.

10 Dec 2023

How did machine learning models perform in identifying hepatitis in patients with diabetes?

The performance of different machine learning models in detecting hepatitis among people with diabetes.

8 Dec 2023

Is your body out of sync? Study finds organs age at varying rates

Research uncovers that human organs age at varying rates, with some showing accelerated aging compared to chronological age, significantly impacting overall health and disease risk. The study used advanced blood plasma proteomics to analyze organ-specific aging in nearly 5,700 adults, linking it to increased risks of heart failure and Alzheimer's disease.

7 Dec 2023

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

Researchers performed a proteomic analysis to identify serologic indicators of organ aging and disease.

7 Dec 2023

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers-;only about one in eight patients survives five years after diagnosis.

6 Dec 2023

Sympathetic nervous system and immune interplay: Key to metabolic regulation

A review in Advanced Science explores the interaction between the immune system and the sympathetic nervous system in regulating vital metabolic organs like the pancreas, liver, and adipose tissues. This comprehensive analysis provides insights into the neuroimmune relationships affecting metabolism, offering potential new therapeutic strategies for metabolic diseases.

5 Dec 2023

Pancreas News and Research

Further Reading

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

New research project seeks to find innovative treatment pathways for Type 2 diabetes and obesity

New model links RNA editing glitch to early-stage type 1 diabetes

Autopsy study provides new insights into yellow fever's impact on the heart

AGA releases the first comprehensive evidence-based guideline on management of pouchitis

UCL scientists receive £997,000 from the Type 1 Diabetes Grand Challenge

Shattering myths: Study reveals new insights on type 1 diabetes and obesity link

Metabolic syndrome linked to higher pancreatic cancer risk, study shows

Epigenetic changes can contribute to the development of type 2 diabetes

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

How did machine learning models perform in identifying hepatitis in patients with diabetes?

Is your body out of sync? Study finds organs age at varying rates

What's my age again? Predicting disease and aging effects by studying organ aging using plasma proteomics data

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Sympathetic nervous system and immune interplay: Key to metabolic regulation

New mechanism revealed for how group A Streptococcus infection reduces type 1 diabetes risk

Postpartum phagocytosis of pancreatic β-cells by macrophages regulates blood glucose levels

Pancreatic vagus nerve stimulation boosts insulin production in mice

LysoPI lipids show promise in boosting insulin secretion in diabetics

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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