Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

CNV in prostate cancer tumors may accurately predict relapse

While active monitoring of serum prostate specific antigen (PSA) levels in men over 50 has greatly improved early detection of prostate cancer, prediction of clinical outcomes after diagnosis remains a major challenge.

7 May 2012

Radiofrequency ablation during breast cancer surgery can provide effective alternative to XRT

Radiofrequency ablation of the lumpectomy site during breast cancer surgery can provide an effective alternative to post-operative external radiation therapy (XRT) and reduce repeat surgeries to achieve clear tumor margins, according to one of the first published long-term studies to examine this new treatment protocol.

5 May 2012

ACR names WDI as Breast Imaging Center of Excellence

Women's Digital Imaging of Ridgewood (WDI) has been named a Breast Imaging Center of Excellence by the American College of Radiology (ACR). The Center of Excellence designation is awarded to facilities that meet the highest standards set by the ACR through peer-review evaluations conducted in each breast imaging modality by board-certified physicians and medical physicists.

5 May 2012

PACSGEAR Image Exchange to be showcased at SIIM 2012

PACSGEAR, the leading provider of imaging connectivity for electronic health records, today announced the PACSGEAR Image Exchange, a cloud-based solution designed to securely upload and share medical images and results between facilities.

5 May 2012

SPECT/CT can change clinical management of thyroid cancer

The use of single positron emission computed tomography (SPECT)/computed tomography (CT) has been reported to change clinical management in a significant number of thyroid cancer patients according to research presented in the May issue of The Journal of Nuclear Medicine.

4 May 2012

Researchers discover two defective genes that cause auriculocondylar syndrome

Researchers at Seattle Children's Research Institute and their collaborators have discovered a pair of defective genes that cause a rare congenital malformation syndrome that can make it impossible for the child to breathe or eat properly without reparative surgery.

4 May 2012

Potential ways for doctors to improve hormone receptor-positive breast cancer treatment

American and Spanish researchers have found potential ways for doctors to improve the treatment of hormone receptor-positive breast cancer even if they lack access to costly multi-gene tests, as they report at the 4th IMPAKT Breast Cancer Conference.

4 May 2012

New genetic pathway influences spread of cancer cells

In a new study from Lawson Health Research Institute, Dr. Joseph Torchia has identified a new genetic pathway influencing the spread of cancer cells. The discovery of this mechanism could lead to new avenues for treatment.

4 May 2012

Competition to celebrate art in medicine

It turns out beauty really is skin deep. A hair follicle or skin specimen that doesn't look like much of anything to the naked eye can become a complex, colorful work of art under a microscope. Mayo Clinic dermatologists struck by the beauty they see in the cellular have started a competition to celebrate art in medicine. The winning entries appear in the May issue of the Journal of Cutaneous Pathology.

3 May 2012

Cone beam CT superior to mutidetector CT for detecting superior semicircular canal dehiscence

Cone beam CT is superior to mutidetector CT for detecting superior semicircular canal dehiscence or the so called third window (a small hole in the bony wall of the inner ear bone that can cause dizziness and hearing loss) and it uses half the radiation dose, a new study shows.

3 May 2012

New clues about why immune system fails to kill tumors in mice

A pioneering approach to imaging breast cancer in mice has revealed new clues about why the human immune system often fails to attack tumors and keep cancer in check. This observation, by scientists at the University of California, San Francisco (UCSF), may help to reveal new approaches to cancer immunotherapy.

3 May 2012

Probiodrug AG, collaborators explain interplay of key suspects in Alzheimer’s

Probiodrug AG (Probiodrug), a biotech company developing products for the treatment of neurodegenerative and inflammatory diseases with a particular focus on Alzheimer's disease (AD), today announced its scientists and academics collaborators published seminal findings on the role of pyroglu Aβ in AD pathology in the May 2, 2012 online edition of the journal Nature (DOI: 10.1038/nature11060). The new findings add to the growing body of evidence that pyroglu Aβ plays a crucial role in the initiation of AD. In addition, the research results further elucidate the mechanism by which pyroglu Aβ triggers neuronal toxicity.

3 May 2012

Grape-derived compound may prevent neurodegenerative disorders involving tau neuropathology

Researchers at Mount Sinai School of Medicine have gained insight into the mechanism by which a pathological brain protein called tau contributes to the progression of Alzheimer's disease (AD) and other neurodegenerative disorders. This finding, published in the most recent issue of the Journal of Biological Chemistry, may provide the basis for future investigations on how to prevent tau from damaging brain circuits involved in cognitive function.

2 May 2012

Antibody that neutralizes enzyme Kallikrein 6 staves off MS

Researchers studying multiple sclerosis(MS) have long been looking for the specific molecules in the body that cause lesions in myelin, the fatty, insulating cells that sheathe the nerves.

30 Apr 2012

Study reveals direct correlation between negative thinking about pain and poor sleep

Chronic pain sufferers who learn to dwell less on their ailments may sleep better and experience less day-to-day pain, according to results of research conducted on 214 people with chronic face and jaw pain.

27 Apr 2012

Change in attitude may ease chronic pain by aiding sleep: Study

26 Apr 2012

A melanoma cloaking protein

Johns Hopkins and Yale scientists have found that melanoma cells use a cloaking protein to hide from immune cells poised to attack the cancer. Nearly 40 percent of their sampling of melanoma tissues contained the B7-H1 protein, also called PD-L1, and scientists say it could be used as a target for new therapies.

26 Apr 2012

AAA to gather for anatomy meeting in conjunction with Experimental Biology 2012

The American Association of Anatomists will gather this week for its annual meeting in conjunction with the Experimental Biology 2012 conference, which will draw more than 14,000 scientists from industry, government and academia. Below are some programming highlights for the anatomy meeting. All presentations will be made at the San Diego Convention Center.

26 Apr 2012

U of A develops new technology that enables personalized medicine

You wouldn't know it from appearances, but a metal cube the size of a toaster, created at the University of Alberta, is capable of performing the same genetic tests as most fully equipped modern laboratories-and in a fraction of the time.

26 Apr 2012

IMPAKT 2012 breast cancer conference to focus on four major areas

"Basic science and clinical medicine move at different pace because they follow different paths. Both however aim at improving strategies to manage cancer patients. We need to efficiently translate the good things from basic science and efficiently implement them in the clinic."

26 Apr 2012