Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Four Mass. hospitals investigate trashing of patient health records, Calif. employers worry about workers using marijuana on job

"Four Massachusetts community hospitals are investigating how thousands of patient health records, some containing Social Security numbers and sensitive medical diagnoses, ended up in a pile at a public dump. The unshredded records included pathology reports with patients' names, addresses, and results of breast, bone, and skin cancer tests, as well as the results of lab work following miscarriages. By law, medical records and documents containing personal identifying information must be disposed of in a way that protects privacy, and leaving them at a dump is probably illegal, privacy lawyers and hospital officials said" (Kowalczyk, 8/13).

13 Aug 2010

Researchers identify second type of complete sporadic disease

A new sporadic prion protein disease has been discovered. Variably protease-sensitive prionopathy, as it has been named, is the second type of complete sporadic disease to be identified since Creutzfeldt-Jakob disease was reported in the 1920s. The landmark finding from the National Prion Disease Pathology Surveillance Center at Case Western Reserve University is published in the August issue of Annals of Neurology.

13 Aug 2010

LabCorp announces collaboration between Esoterix Clinical Trials Services, Clearstone Central Laboratories

Laboratory Corporation of America Holdings announced today a collaboration between Esoterix Clinical Trials Services, a division of LabCorp, and Clearstone Central Laboratories, a global central laboratory specializing in drug development and pharmaceutical services.

13 Aug 2010

Severe inflammatory response to initial UTI causes bladder damage: Research

The immune system may open the door to recurrent urinary tract infections (UTIs) by overdoing its response to an initial infection, researchers at Washington University School of Medicine in St. Louis have found.Researchers showed in mice that severe inflammatory responses to an initial UTI cause bladder damage and allow infection to persist longer. After one to two weeks of infection, the bladder wall undergoes additional changes that leave mice more vulnerable to later infection. Suppressing the immune system during initial infection decreases these vulnerabilities, they report Aug. 12 in PLoS Pathogens.

13 Aug 2010

Problems with analytical study design and data misinterpretation leads to biomarker failure: Report

The boom in cancer biomarker investments over the past 25 years has not translated into major clinical success. The reasons for biomarker failures include problems with study design and interpretation, as well as statistical deficiencies, according to an article published online August 12 in The Journal of the National Cancer Institute.

13 Aug 2010

Merlin protein controls adult cell activity to cause liver cancer

A protein known to be involved in a rare hereditary cancer syndrome may have a role in the regulation of liver stem cells and the development of liver cancer. In the August 15 issue of Genes & Development, a Massachusetts General Hospital (MGH) research team describes finding that the protein called merlin, encoded by the NF2 (neurofibromatosis type 2) gene, controls the activity of adult stem cells that give rise to the two major types of liver cells.

13 Aug 2010

Transgenomic second-quarter net loss increases to $1.1 million

Transgenomic, Inc. today reported financial results for the three and six months ended June 30, 2010, and provided a business update.

13 Aug 2010

Intellect Neurosciences receives patent for insulin sensitizer drugs

Intellect Neurosciences, Inc., a biopharmaceutical company with an internal preclinical and clinical-stage pipeline and licenses with major pharmaceutical companies covering products in late-stage clinical trials, announced today that its Chairman & CEO, Dr. Daniel Chain, was granted a patent by the European Patent and Trademark Office related to the use of insulin sensitizers for the prevention and treatment of memory loss and dementia. Insulin sensitizer drugs include Rosiglitazone and Pioglitazone, which have been approved for the treatment of type II diabetes mellitus.

12 Aug 2010

Researchers find transposons determine differences in physical traits, disease risks

Building on a tool that they developed in yeast four years ago, researchers at the Johns Hopkins University School of Medicine scanned the human genome and discovered what they believe is the reason people have such a variety of physical traits and disease risks.

12 Aug 2010

Research identifies abnormal huntingtin protein critical for mitosis and cell fate determination

New research finds that a protein that is often mutated in Huntington's disease (HD) plays an unexpected role in the process of neurogenesis. The research, published by Cell Press in the August 12 issue of the journal Neuron, provides new insight into HD pathology and has even broader implications for human health and disease.

12 Aug 2010

AssureRx Health achieves CAP accreditation for laboratory pharmacogenetic testing services

AssureRx Health, Inc. today announced that it has received accreditation from the College of American Pathologists for the delivery of high-quality, reliable laboratory pharmacogenetic testing services that meet or exceed regulatory laboratory standards and ensure commitment to patient care.

11 Aug 2010

Intellect Neurosciences receives patent for Alzheimer's disease vaccine

Intellect Neurosciences, Inc a biopharmaceutical company with an internal preclinical and clinical-stage pipeline and licenses with major pharmaceutical companies covering products in late-stage clinical trials, announced that it has received a Notice of Allowance from the United States Patent and Trademark Office related to RV01 and RV02, the Company's two lead vaccine candidates. The Notice of Allowance is a written communication stating that the patent application has been allowed and will be granted as a new patent. RV01 and RV02, generated using the Company's RECALL-VAX technology, have the potential to delay the onset of or prevent Alzheimer's disease in individuals susceptible by age, genetic or other risk factor.

11 Aug 2010

SMI/Omega development team receives fund to develop prototype fast multispectral endoscope

Cascade Technologies, Inc., announced today that its wholly-owned subsidiary Spectral Molecular Imaging, Inc. (SMI) will receive NIH research funding through a collaboration with Omega Optical of Brattleboro, Vermont. This effort will accelerate development of a new class of medical endoscopes enhanced with proprietary multispectral imaging technology. The principal investigators on the project are Dr. Gary Carver, Director of Research at Omega Optical, and Dr. Daniel L. Farkas, Chairman and CEO of SMI.

11 Aug 2010

Clarient receives patent for Mammostrat breast cancer prognostic test

Clarient, Inc. a premier technology and services resource for pathologists, oncologists and the pharmaceutical industry, today announced that the United States Patent and Trademark Office and the European Patent Office have allowed patents covering the technology behind Clarient Insight Dx Mammostrat, a test designed to aid in the classification of the risk of recurrence of breast cancer following surgery and initial treatment.

11 Aug 2010

ACD launches RNAscope Formalin-Fixed, Paraffin-Embedded Assay Kit

Advanced Cell Diagnostics, Inc., announces the launch and immediate availability of RNAscope™ FFPE Assay Kit, a line of RUO products designed to detect RNA biomarkers in routine Formalin-Fixed, Paraffin-Embedded tissue specimens with single molecule sensitivity.

From Advanced Cell Diagnostics 11 Aug 2010

Language Line University offers new scalable online training tool for medical interpreters

Language Line(R) University, the interpreter assessment and training division of Language Line Services, an over-the-phone and video interpretation services provider, is offering a new scalable online training tool for medical interpreters. LLU Web Advanced Medical Training for Interpreters, the first of its kind in the industry, combines 15 hours of self-paced Web activities with 10 hours of live over-the-phone instructor-led sessions. Completion of the course qualifies participants to receive 10 continuing education points from the American Translators Association.

10 Aug 2010

UT Southwestern enters partnership with Sun Yat-sen University to promote scientific research

UT Southwestern Medical Center has entered into an academic and scientific partnership with Sun Yat-sen University and its First Affiliated Hospital in Guangzhou, China. The first international institutional affiliation for UT Southwestern and a first step in implementing the global health initiative that is one of the medical center's current strategic priorities, the partnership was developed to promote joint scientific research, educational, and training activities.

10 Aug 2010

LabCorp board authorizes new $250 million stock repurchase program

Laboratory Corporation of America® Holdings today announced that its Board of Directors has authorized a new stock repurchase program under which LabCorp may purchase up to an additional aggregate of $250 million of its Common Stock from time-to-time.

10 Aug 2010

New scaffold supports growth, integration of stem cell-derived cardiac muscle cells

These days people usually don't die from a heart attack. But the damage to heart muscle is irreversible, and most patients eventually succumb to congestive heart failure, the most common cause of death in developed countries.Stem cells now offer hope for achieving what the body can't do: mending broken hearts. Engineers and physicians at the University of Washington have built a scaffold that supports the growth and integration of stem cell-derived cardiac muscle cells. A description of the scaffold, which supports the growth of cardiac cells in the lab and encourages blood vessel growth in living animals, is published this week in the Proceedings of the National Academy of Sciences.

10 Aug 2010

New microchip technology to detect oral cancer

A new test for oral cancer, which a dentist could perform by simply using a brush to collect cells from a patient's mouth, is set to be developed by researchers at the University of Sheffield and Sheffield Teaching Hospitals NHS Foundation Trust.

10 Aug 2010

Pathology News and Research

Further Reading

Four Mass. hospitals investigate trashing of patient health records, Calif. employers worry about workers using marijuana on job

Researchers identify second type of complete sporadic disease

LabCorp announces collaboration between Esoterix Clinical Trials Services, Clearstone Central Laboratories

Severe inflammatory response to initial UTI causes bladder damage: Research

Problems with analytical study design and data misinterpretation leads to biomarker failure: Report

Merlin protein controls adult cell activity to cause liver cancer

Transgenomic second-quarter net loss increases to $1.1 million

Intellect Neurosciences receives patent for insulin sensitizer drugs

Researchers find transposons determine differences in physical traits, disease risks

Research identifies abnormal huntingtin protein critical for mitosis and cell fate determination

AssureRx Health achieves CAP accreditation for laboratory pharmacogenetic testing services

Intellect Neurosciences receives patent for Alzheimer's disease vaccine

SMI/Omega development team receives fund to develop prototype fast multispectral endoscope

Clarient receives patent for Mammostrat breast cancer prognostic test

ACD launches RNAscope Formalin-Fixed, Paraffin-Embedded Assay Kit

Language Line University offers new scalable online training tool for medical interpreters

UT Southwestern enters partnership with Sun Yat-sen University to promote scientific research

LabCorp board authorizes new $250 million stock repurchase program

New scaffold supports growth, integration of stem cell-derived cardiac muscle cells

New microchip technology to detect oral cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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