Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Discovery of two important molecules that underlie the pathology of lupus, particularly kidney disease

Kidney damage associated with the autoimmune disease lupus is linked to a malfunction of immune cells that causes them to congregate in and attack the organs, researchers at UT Southwestern Medical Center have discovered in a mouse study.

22 Apr 2009

Researchers identify gene linked to skeletal muscle disease and vision deficits

Skeletal muscle disease and vision deficits might seem unrelated, but a frog model of muscular dystrophy shows it is not such a leap.

22 Apr 2009

Exposure to combination of two pesticides increase risk of Parkinson's by 75 percent

The fertile soil of California's Central Valley has long made it famous as one of the nation's prime crop-growing regions.

22 Apr 2009

Discovery of 12 proteins associated with pediatric multiple sclerosis

A group of 12 proteins associated with pediatric multiple sclerosis (MS) have been discovered for the first time by a team of neurology and pathology researchers at Stony Brook University Medical Center.

22 Apr 2009

New drug to target tumor cells and blood vessels

Researchers at the University of Southern California have identified a new drug compound that appears to target tumor cells and surrounding blood vessels without the negative side effects typically associated with Cox-2 inhibitors.

21 Apr 2009

New drug to target tumor cells and blood vessels

21 Apr 2009

Genetic source of rare cancer pleuropulmonary blastoma discovered

The search for the cause of an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about how the cancer develops and potentially sheds light on the development of other cancers.

20 Apr 2009

Newly discovered epidermal growth factor receptor active in human pancreatic cancers

Finally some promising news about pancreatic cancer, one of the most fatal cancers, due to the difficulties of early detection and the lack of effective therapies: Johns Hopkins University pathologist Akhilesh Pandey has identified an epidermal growth factor receptor aberrantly active in approximately a third of the 250 human pancreatic cancers studied.

20 Apr 2009

New biomarker may predict aggressiveness of chronic lymphocytic leukemia

Scientists at the University of California, San Diego and the Moores UCSD Cancer Center have evidence of a potential new biomarker to predict the aggressiveness of an often difficult-to-treat form of leukemia.

20 Apr 2009

Coffee, caffeine and amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages key neurons in the brain and spinal cord.

20 Apr 2009

Computational model examines the pathways of Alzheimer's that strikes at the young

Alzheimer's disease (AD) is a tragic disease that robs an individual of their memory and mental capacity.

20 Apr 2009

Survival mode that protects cells when oxygen is low also slows aging

A biochemical pathway that helps keep cells alive when oxygen is low also plays a role in longevity and resistance against some diseases of old age, according to a report to be published April 16 in the journal Science.

16 Apr 2009

New insights Huntington disease development

A global analysis of brain proteins over a 10-week period in a mouse model of Huntington Disease has revealed some new insights into this complex neurodegenerative disorder.

16 Apr 2009

Autopsy study links prostate cancer to single rogue cell

One cell…one initial set of genetic changes - that's all it takes to begin a series of events that lead to metastatic cancer.

16 Apr 2009

Autopsy study links prostate cancer to single rogue cell

One cell...one initial set of genetic changes - that's all it takes to begin a series of events that lead to metastatic cancer. Now, Johns Hopkins experts have tracked how the cancer process began in 33 men with prostate cancer who died of the disease. Culling information from autopsies, their study points to a set of genetic defects in a single cell that are different for each person's cancer.

16 Apr 2009