Pathophysiology News and Research

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Intensive blood pressure treatment may lead to positive change in brain structures linked with brain health

Among people who received more intensive treatment for high blood pressure, evaluations of MRI scans indicated a positive change in brain structures involved in its ability to clear toxins and other byproducts, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Lifestyle-related metabolite biomarker may be a target to reduce stroke risk in Black adults

Researchers have identified a lifestyle-related metabolite biomarker called gluconic acid that is associated with high blood pressure, increased risk of ischemic stroke, eating a Southern diet, lower level of education and lack of exercise, among Black adults, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Food swamp environments associated with greater odds of stroke among adults 50 and older

Adults ages 50 and older who lived near dense fast food and unhealthy food environments known as "food swamps" had a higher risk of stroke compared to those who lived in areas with fewer retail and fast food choices, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

People with poor oral health may be more likely to show signs of declining brain health

Taking care of your teeth and gums may offer benefits beyond oral health such as improving brain health, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

New smartphone application may recognize common stroke symptoms in real time

A new smartphone application called FAST.AI may help people who are having a stroke or their family and caregivers recognize common stroke symptoms in real time, prompting them to quickly call 9-1-1, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Mexican American stroke survivors more likely to use less intensive forms of rehabilitation than non-Hispanic patients

Mexican American stroke survivors in a South Texas study, were more likely to use less intensive forms of rehabilitation services than their non-Hispanic white peers, and nearly one-third of all the stroke survivors did not receive any rehabilitation within 90 days of their stroke, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Black and Hispanic stroke survivors in the U.S. less likely to be treated for certain complications

Analysis of 20 years of electronic health records across the U.S. finds Black and Hispanic stroke survivors were less likely than white stroke survivors to receive treatment for common complications during the first year after their stroke, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Bone marrow transplants may prevent blood vessel disease in patients with sickle cell disease

Bone marrow transplants prevented or improved blood vessel disease in the brains of adults with sickle cell disease, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Dual antiplatelet therapy for minor or a warning stroke is underused especially among women

Despite evidence that starting two blood-thinning medications shortly after a minor stroke or a warning stroke (transient ischemic attack - TIA) may prevent a second – possibly more serious – clot-caused stroke within a few months, the treatment regimen is underused especially among women, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Trial shows the benefit of using a celery seed-derived medication after clot treatment in stroke patients

People who had an ischemic (clot-caused) stroke and were treated with a clot-busting medication and/or mechanical clot removal and also received butylphthalide, a medication initially compounded from celery seed, experienced milder neurological symptoms with better functioning at three months after the stroke, compared to stroke patients who had their clots treated but received a placebo medication, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Study shows COVID-19 induces body fat and other metabolic changes

In a recent study published in the journal Cureus, researchers explored the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and levels of serum insulin, body fat distribution, and insulin resistance (IR) estimated by homeostasis model assessment (HOMA).

29 Jan 2023

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

Under the supervision of four professors from the UMCG departments of Gastroenterology and Hepatology and Pathology and Medical Biology, Bourgonje conducted doctoral research on the predictive value of biomarkers for inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis.

29 Jan 2023

PLK1-mTOR axis may be a promising therapeutic target for sepsis, study suggests

Sepsis, one of the most acute and serious disease complications in the intensive care unit, is caused by various infections and results in life-threatening organ dysfunction.

26 Jan 2023

Study finds link between self-stigma and glycated hemoglobin in people with type 1 diabetes

Individuals with chronic medical conditions may experience self-stigma, or negative beliefs, emotional reactions, and behaviors towards themselves as a result of their illness.

25 Jan 2023

What is the association between COVID-19, cardiovascular disease, and mortality?

In a new study, researchers evaluated the association between COVID-19 (coronavirus disease 2019) and CVD (cardiovascular disease) and/or death.

23 Jan 2023

Study reviews mechanistic data on new methods of allergy prevention and treatment

In a recent article published in Science Translational Medicine, researchers reviewed the cause and the underlying pathophysiology of allergic diseases.

23 Jan 2023

New research evaluates clinical trials investigating post-acute COVID-19 syndrome treatment

In a recent article published in Clinical Microbiology and Infection, researchers reviewed all registered trials currently investigating potential treatment options for post-acute coronavirus disease 2019 (COVID-19) syndrome (PACS).

23 Jan 2023

Several genes and individual genetic variations associated with atrial fibrillation discovered

In the largest genetic study of heart arrhythmia to date, researchers led by Kazuo Miyazawa and Kaoru Ito at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan report the discovery of several genes and individual genetic variations that are associated with atrial fibrillation.

19 Jan 2023

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Researchers explored the relationship between the development of goblet inflammatory cells and the age-related pathophysiology of SARS-CoV-2.

19 Jan 2023

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Mice exposed to World Trade Center dust exhibit a significant impairment in spatial recognition and short- and long-term memory, as well as changes in genes related to immune-inflammatory responses and blood-brain barrier disruption, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai and published January 17 in the Journal of Alzheimer's Disease.

17 Jan 2023

Pathophysiology News and Research

Intensive blood pressure treatment may lead to positive change in brain structures linked with brain health

Lifestyle-related metabolite biomarker may be a target to reduce stroke risk in Black adults

Food swamp environments associated with greater odds of stroke among adults 50 and older

People with poor oral health may be more likely to show signs of declining brain health

New smartphone application may recognize common stroke symptoms in real time

Mexican American stroke survivors more likely to use less intensive forms of rehabilitation than non-Hispanic patients

Black and Hispanic stroke survivors in the U.S. less likely to be treated for certain complications

Bone marrow transplants may prevent blood vessel disease in patients with sickle cell disease

Dual antiplatelet therapy for minor or a warning stroke is underused especially among women

Trial shows the benefit of using a celery seed-derived medication after clot treatment in stroke patients

Study shows COVID-19 induces body fat and other metabolic changes

Doctoral research presents predictive value of biomarkers for inflammatory bowel diseases

PLK1-mTOR axis may be a promising therapeutic target for sepsis, study suggests

Study finds link between self-stigma and glycated hemoglobin in people with type 1 diabetes

What is the association between COVID-19, cardiovascular disease, and mortality?

Study reviews mechanistic data on new methods of allergy prevention and treatment

New research evaluates clinical trials investigating post-acute COVID-19 syndrome treatment

Several genes and individual genetic variations associated with atrial fibrillation discovered

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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