Pathophysiology News and Research

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Is there an association between sleep-disordered breathing and Alzheimer's disease?

Researchers evaluated the impact of sleep-disordered breathing (SDB) on neuroimaging biomarkers of Alzheimer's disease (AD).

21 Aug 2023

How effective is the keto diet for managing PCOS?

Scientists discuss the metabolic advantages of the ketogenic diet in the management of polycystic ovarian syndrome.

21 Aug 2023

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Researchers used genetically modified animal models to investigate the role of the newly discovered Traf2- and NCK-interacting protein kinase (TNIK) in obesity and metabolic dysfunction.

15 Aug 2023

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

A new paper has shown how Alzheimer’s disease pathology comes into being over a period of almost three decades.

10 Aug 2023

New tool can identify psoriasis patients at risk for psoriatic arthritis

In research published in Arthritis & Rheumatology, investigators developed and validated a tool called PRESTO that identifies patients with psoriasis who face an elevated risk for developing psoriatic arthritis and may therefore benefit from preventive therapies.

9 Aug 2023

Study finds genetic overlap between IBS, gastrointestinal diseases, and psychiatric disorders

Researchers characterized the genetic architecture of IBS and investigated genetic overlap with gastrointestinal and psychiatric phenotypes.

8 Aug 2023

Is there an association between migraines and the onset of inflammatory bowel disease?

The link between migraines and the new onset of inflammatory bowel disease (IBD).

4 Aug 2023

Study provides new insights into the intricate cellular processes driving heterotopic ossification

In a new study published on 21 July 2023 by the journal Bone Research, a team of researchers from Johns Hopkins University, using a combination of lineage tracing and single-cell RNA sequencing (scRNA-seq), delved into the contribution of synovial/tendon sheath progenitor cells to heterotopic bone formation.

1 Aug 2023

The effects of oxidative stress on women’s fertility

Scientists review existing literature to assess the relationship between oxidative stress and female infertility.

1 Aug 2023

How effective is physical activity in alleviating obesity-related inflammation in diabetes?

Scientists determine whether physical activity can be used as an effective intervention to mitigate obesity-related inflammation in diabetes.

1 Aug 2023

New method allows the discovery of specific inhibitors of lactate transporter

Scientists from the Giulio Superti-Furga Lab at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, have developed a new method that allows the discovery of specific inhibitors of a lactate transporter associated with cancer and other disease areas.

28 Jul 2023

Targeting chronic endometritis: study reveals potential diagnostic markers

Researchers investigated the gene expression signatures and immune cell involvement in chronic endometritis (CE) for potential diagnostic markers.

25 Jul 2023

Bibliometric analysis reveals research trends connecting Alzheimer's disease and the gut microbiome

Researchers utilize bibliometric analysis to investigate the relationship between the gut microbiome and Alzheimer's disease pathogenesis.

25 Jul 2023

The association of dietary patterns with Alzheimer’s disease and related dementia symptomology

A new paper discusses the impact of diet on the risk of AD, in which researchers describe the interrelationship between specific nutrients, dietary patterns, other risk factors for AD, and psychosocial factors driving these patterns.

24 Jul 2023

Exclusion of chronic kidney disease patients from cardiovascular trials leaves significant evidence gaps

Study looks at how and where patients with CKD have been excluded from CVD RCTs over the last two decades.

24 Jul 2023

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

Researchers pursued insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of MS.

21 Jul 2023

Northwestern Medicine scientists discover new therapeutic target for Parkinson’s disease

Northwestern Medicine scientists have uncovered a new mechanism by which mutations in a gene parkin contribute to familial forms of Parkinson's disease.

19 Jul 2023

New proteomic insights: cerebrospinal fluid biomarkers show promise in detecting dementia with Lewy bodies

Researchers conducted cerebrospinal fluid (CSF) proteome profiling and identified CSF proteins.

17 Jul 2023

Superagers more likely to have greater movement speed than typical older adults

People in their eighties who can recall everyday events and life experiences as well as someone 20 to 30 years younger – known as superagers – are also more likely to have greater movement speed than typical older adults.

13 Jul 2023

Investigating the role of T-cell immunity in long COVID

Researchers investigates the persistence of symptoms and the immune response in patients recovering from COVID-19.

13 Jul 2023

Pathophysiology News and Research

Is there an association between sleep-disordered breathing and Alzheimer's disease?

How effective is the keto diet for managing PCOS?

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

New tool can identify psoriasis patients at risk for psoriatic arthritis

Study finds genetic overlap between IBS, gastrointestinal diseases, and psychiatric disorders

Is there an association between migraines and the onset of inflammatory bowel disease?

Study provides new insights into the intricate cellular processes driving heterotopic ossification

The effects of oxidative stress on women’s fertility

How effective is physical activity in alleviating obesity-related inflammation in diabetes?

New method allows the discovery of specific inhibitors of lactate transporter

Targeting chronic endometritis: study reveals potential diagnostic markers

Bibliometric analysis reveals research trends connecting Alzheimer's disease and the gut microbiome

The association of dietary patterns with Alzheimer’s disease and related dementia symptomology

Exclusion of chronic kidney disease patients from cardiovascular trials leaves significant evidence gaps

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

Northwestern Medicine scientists discover new therapeutic target for Parkinson’s disease

New proteomic insights: cerebrospinal fluid biomarkers show promise in detecting dementia with Lewy bodies

Superagers more likely to have greater movement speed than typical older adults

Investigating the role of T-cell immunity in long COVID

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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