Peptides News and Research

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Scripps Research develops breakthrough technique for adding unique amino acids to proteins

It's a dogma taught in every introductory biology class: Proteins are composed of combinations of 20 different amino acids, arranged into diverse sequences like words.

11 Sep 2024

New hydrogel system could extend semaglutide dosing to once a month for type 2 diabetes patients

French researchers have developed a new drug delivery system that could cut the dosing schedule for the type 2 diabetes and weight control drug semaglutide to just once a month, according to new research to be presented at this year's annual meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept).

9 Sep 2024

Study explores the effects of hyperosmotic stress on microglial cells

Microglia are the brain's immune cells known to play a vital role in maintaining neural function and responding to potential threats.

4 Sep 2024

How can microdialysis benefit drug development?

In this interview, discover how Charles River uses the power of microdialysis for drug development as well as CNS therapeutics.

From Charles Rivers Laboratories Neuroscience 3 Sep 2024

Garlic’s antioxidant and nitric oxide boosting effects may help lower blood pressure

Scientific evidence supports garlic's antihypertensive effects, detailing the mechanisms of action and key compounds that contribute to cardiovascular benefits.

3 Sep 2024

Scientists reveal global catalog of microbial small proteins, unlocking microbiome secrets

Researchers developed a global catalog of nearly one billion small open reading frames (smORFs) from microbial genomes, revealing significant protein diversity, particularly in archaea, and providing new tools for microbiome research.

2 Sep 2024

$FINEARTS-HF trial shows finerenone benefits for heart failure with preserved ejection fraction$

FINEARTS-HF trial shows finerenone benefits for heart failure with preserved ejection fraction

Finerenone reduced heart failure (HF) events and cardiovascular death in patients with HF and mildly reduced (HFmrEF) or preserved ejection fraction (HFpEF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

New method revolutionizes DNA-encoded chemical libraries

Nowadays, there's lots of buzz about spectacular new medical treatments such as personalised cancer therapy with modified immune cells or antibodies.

2 Sep 2024

Tirzepatide outperforms insulin in controlling diabetes and promoting weight loss in clinical trials

Tirzepatide, a once-weekly dual agonist, outperforms long-acting insulin in reducing HbA1c, body weight, and improving cardiovascular markers in Type 2 diabetes patients.

2 Sep 2024

16 promising postdoctoral scientists awarded Damon Runyon Fellowships for cancer research

The Damon Runyon Cancer Research Foundation has named 16 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

28 Aug 2024

Scientists discover how a gut insulin antagonist controls fat loss in C. elegans by modulating brain signals

Researchers have identified an endogenous insulin antagonist, INS-7, in Caenorhabditis elegans that modulates fat loss by inhibiting a gut-to-brain signaling pathway involving the neuropeptide FLP-7.

27 Aug 2024

Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

Synthetic immunology, an innovative field of research which could lead to fundamentally new approaches and methods in the treatment of infectious diseases and cancer, is the topic of an article in the "Perspectives" section of the journal "Nature Nanotechnology". Herein, Heidelberg researchers Prof. Dr. Kerstin Göpfrich, Prof. Dr. Michael Platten, Prof. Dr. Friedrich Frischknecht, and Prof. Dr. Oliver T. Fackler describe a so-called bottom-up approach that uses the toolbox of nanotechnology and synthetic biology to construct systems from molecular building blocks and specifically equip them with immune functions.

27 Aug 2024

Human gut microbiome: A source of new antibiotic peptides

Researchers identified 323 peptide-based antimicrobials from the human microbiome, with 71% showing significant antibacterial activity, and the lead peptide, prevotellin-2, matching the efficacy of polymyxin B in both in vitro and in vivo models.

25 Aug 2024

New analytical method for identifying cancer cell targets

What are the characteristics of a cancer cell that are recognized by the immune system? Knowledge of the potential target structures for the immune cells is a basic prerequisite for the development of personalized cancer immunotherapies. Scientists from the German Cancer Research Center (DKFZ) and the NCT Heidelberg are publishing a highly sensitive method based on mass spectroscopy to identify such tumor-specific "neoepitopes". The analytical method is designed to detect these low-abundance protein fragments and requires minimal amounts of sample material.

23 Aug 2024

Cancer drug holds promise as a new treatment for neurodegenerative diseases

A type of drug developed for treating cancer holds promise as a new treatment for neurodegenerative diseases such as Alzheimer's, according to a recent study by researchers at Penn State, Stanford University and an international team of collaborators.

22 Aug 2024

Peptides News and Research

Scripps Research develops breakthrough technique for adding unique amino acids to proteins

New hydrogel system could extend semaglutide dosing to once a month for type 2 diabetes patients

Study explores the effects of hyperosmotic stress on microglial cells

How can microdialysis benefit drug development?

Garlic’s antioxidant and nitric oxide boosting effects may help lower blood pressure

Scientists reveal global catalog of microbial small proteins, unlocking microbiome secrets

FINEARTS-HF trial shows finerenone benefits for heart failure with preserved ejection fraction

New method revolutionizes DNA-encoded chemical libraries

Tirzepatide outperforms insulin in controlling diabetes and promoting weight loss in clinical trials

16 promising postdoctoral scientists awarded Damon Runyon Fellowships for cancer research

Scientists discover how a gut insulin antagonist controls fat loss in C. elegans by modulating brain signals

Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

Human gut microbiome: A source of new antibiotic peptides

New analytical method for identifying cancer cell targets

Cancer drug holds promise as a new treatment for neurodegenerative diseases

Gut molecule blocks fat burning during fasting in C. elegans

Breakthrough compound targets appetite and tau protein in obesity and Alzheimer's

Understanding gluten's role in autoimmunity and inflammation

Uncovering new antibiotics from the human gut microbiome

Cross-reactive T cells link SARS-CoV-2 to autoimmune triggers in MIS-C

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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