Peptides News and Research

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Persistent amyloidosis following suppression of Ab production in a transgenic model of Alzheimer disease

Alzheimer Disease (AD) is characterized by hallmark lesions called amyloid plaques in the brain.

20 Nov 2005

Genetically modified allow scientists to examine the potential usefulness of new therapies for Alzheimer's disease

Researchers with the University of Florida and the California Institute of Technology have developed a new strain of genetically modified mice that allow scientists to examine the potential usefulness of new therapies for Alzheimer's disease.

20 Nov 2005

Molecular origins of diabetes

An unexpected twist to a discovery reported just two months ago may significantly improve our understanding about the molecular origins of diabetes.

14 Nov 2005

First clinical study of FX06 treatment against damage caused by heart attacks

Central to the study is FXO6, a peptide developed and patented by Austro-American company Fibrex Medical. Fibrex will now test the tolerability and pharmacokinetics of FX06 in humans. The peptide reduces inflammatory responses of the heart muscle that can arise after treatment for a myocardial infarction. Tests will begin immediately on the first - healthy - subjects at the Vienna General Hospital.

7 Nov 2005

Resveratrol effective in lowering amyloid-beta peptides

A study published in the November 11 issue of the Journal of Biological Chemistry shows that resveratrol, a compound found in grapes and red wine, lowers the levels of the amyloid-beta peptides which cause the telltale senile plaques of Alzheimer's disease.

7 Nov 2005

New high-resolution data on intact ribosome

A new, sharper picture of the nano-machine that translates our genetic program into proteins promises to help researchers explain how some types of antibiotics work and could lead to the design of better ones.

7 Nov 2005

New targeted cancer drug delivery system

Prostate, breast and other cancer patients may be offered a new, stauncher targeted drug delivery system to treat their diseases in the next decade.

3 Nov 2005

Cancer Vaccine - Synthetically generated glycopeptides from tumor cells can stimulate the formation of specific antibodies

Tumor cells and healthy somatic cells differ in the structures on their surfaces. In principle, it should thus be possible to develop a vaccine that causes a patient’s immune system to form antibodies that attack and destroy tumor cells while sparing healthy cells.

3 Nov 2005

Vaginal gel shown to protect female monkeys against an HIV-like virus

Research with female monkeys at the Tulane National Primate Research Center has for the first time shown that three different anti-viral agents in a vaginal gel protect the animals against an HIV-like virus.

1 Nov 2005

Hormone found naturally in the body has the ability to cause limited weight loss

Research at the Oregon National Primate Research Center (ONPRC) at Oregon Health & Science University has demonstrated that a hormone found naturally in the body has the ability to cause limited weight loss. Specifically, the research revealed that peptide YY (PYY) can reduce food consumption in the morning, leading to a mild level of weight loss in the short term.

30 Oct 2005

Antisense molecules may hold promise in treating brain chemical problems such as Alzheimer's

Saint Louis University research shows a new class of drugs may hold promise in treating brain chemical problems such as Alzheimer's disease, says the principal investigator of research published in an early on-line version of Peptides.

25 Oct 2005

Leeches, useful tools in the treatment of cardiovascular diseases

The leech has recently confirmed its biomedical interest for scientists by showing that it contains an extensive list of new potential molecules that may become useful tools in the treatment of cardiovascular diseases.

24 Oct 2005

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

A molecule that has long been an obstacle to cancer chemotherapy and drug treatments for brain disorders may soon become an ally in the fight against Alzheimer's disease, according to researchers at Washington University School of Medicine in St. Louis and the University of Rochester.

20 Oct 2005

Alzheimer disease and the blood brain barrier

Increased production of the amyloid-beta (Abeta) peptide can lead to Abeta aggregation and buildup in the brain and rare familial forms of early onset Alzheimer disease (AD).

20 Oct 2005

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Reporting in two companion papers in the October 19 issue of the Journal of Neuroscience, investigators from the Gladstone Institute of Neurological Disease show in genetically engineered mouse models of the disease that the accumulation of Alzheimer-related neurotoxic amyloid-beta (Aâ) peptides can deplete key proteins in a specific memory center of the brain.

18 Oct 2005

dnaJP1 - novel drug for the treatment of rheumatoid arthritis

Researchers at the University of California, San Diego (UCSD) School of Medicine have announced successful completion of Phase II clinical trials of a novel drug for the treatment of rheumatoid arthritis (RA), one that works without suppressing the patient's immune system.

16 Oct 2005