Peripheral Artery Disease News and Research

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Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. These blockages can result in severe pain for patients, limited physical mobility, and life-threatening non-healing leg ulcers. According to the American Heart Association, this condition affects approximately 8 to 12 million Americans. With only about 25 percent of PAD patients undergoing treatment, it is a disease that is largely under-diagnosed and under-treated. If left untreated, PAD can lead to critical leg ischemia, a condition where not enough blood is being delivered to the leg to keep the tissue alive. Total loss of circulation to the legs and feet can cause gangrene and lead to amputation.

New embolization procedure may bring hope to men with enlarged prostate

A new interventional radiology treatment, prostatic artery embolization, may bring hope to men with debilitating symptoms caused by an enlarged prostate, say the group of researchers who pioneered its use.

26 Mar 2012

Vascular Magnetics to advance development of new drug delivery system for PAD

Vascular Magnetics, the first start-up company spun off by The Children's Hospital of Philadelphia, has raised $7 million to advance development of an innovative drug delivery system using magnetically targeted nanoparticles to treat peripheral artery disease.

28 Feb 2012

Screening events to find out risk for heart attack or stroke

If you could find out if you had an increased risk of heart attack or stroke, wouldn't you want to know? Even if you are fit and healthy, coronary artery disease (CAD) or peripheral artery disease (PAD) are conditions with little to no symptoms and can put you at an increased risk of heart attack or stroke.

20 Feb 2012

Novel stem-cell technique to enhance bone growth

A research team led by UC Davis Health System scientists has developed a novel technique to enhance bone growth by using a molecule which, when injected into the bloodstream, directs the body's stem cells to travel to the surface of bones.

7 Feb 2012

Interim results from Spectranetics laser atherectomy catheter study on ISR

Spectranetics Corporation today announced six month interim results from the PATENT (Photo-Ablation using the TURBO-Booster and Excimer Laser for In-Stent Restenosis Treatment) study evaluating the safety and efficacy of the Spectranetics peripheral laser atherectomy catheters for the treatment of in-stent restenosis (ISR) in the femoropopliteal artery in the leg.

3 Feb 2012

Positive outcomes from Boston Scientific's Epic Stent trial on iliac artery disease

Boston Scientific Corporation reports nine-month clinical endpoint data from its ORION trial, demonstrating excellent outcomes for the Company's Epic Self-Expanding Nitinol Stent System in patients with iliac artery disease, a form of peripheral artery disease associated with severe leg pain caused by insufficient blood flow.

16 Jan 2012

Abbott commences Esprit drug eluting BVS trial in peripheral artery disease

Abbott today announced the initiation of ESPRIT I, a first-of-its-kind clinical trial in Europe evaluating the safety and performance of the novel Esprit drug eluting bioresorbable vascular scaffold (BVS) for the treatment of blockages in the superficial femoral arteries (SFA) and iliac arteries that have resulted in claudication.

23 Dec 2011

AtheroNova establishes clear development plan for AHRO-001 after positive FDA feedback

AtheroNova Inc., a biotech company focused on the research and development of compounds to regress atherosclerotic plaque has established a clear development plan, including Phase I and Phase II protocol outlines, based on the recently finalized minutes of its pre-IND meeting with the U.S. Food and Drug Administration (FDA) for its AHRO-001, a compound for the treatment of atherosclerosis.

15 Dec 2011

Enrollment complete in SUSTAIN Phase 2b clinical trial for atherosclerotic CVD

Resverlogix Corp. today announced that SUSTAIN, a Phase 2b clinical trial comprised of 176 subjects, is fully enrolled.

28 Nov 2011

Pall applies patent with USPTO for disposable, closed cell collection and seeding system

Pall Corporation, a global leader in filtration, separation and purification, has applied for a patent with the United States Patent and Trademark Office (USPTO) for a disposable, closed cell collection and seeding system that is being developed for use in ground-breaking vein regeneration procedures.

From Pall Corporation 23 Nov 2011

NYU Langone cardiovascular experts present new research findings at AHA 2011

Experts from the Cardiac & Vascular Institute at NYU Langone Medical Center presented new research findings at the American Heart Association Scientific Sessions 2011 held November 12-16, 2011 in Orlando, Florida.

18 Nov 2011

Supervised exercise more effective than stenting or medication for PAD

Supervised exercise was shown to be more effective than stenting or medication for improved walking ability in patients with peripheral artery disease. The findings from a national study were reported today at the 2011 American Heart Association Scientific Sessions meeting.

17 Nov 2011

Risk of heart failure appears to be higher among low-income seniors

The risk of heart failure appears to be higher among low-income seniors — even those with a college education — according to research from the University of Alabama at Birmingham presented during the 2011 American Heart Association Scientific Sessions.

15 Nov 2011

FDA approves Medtronic's Assurant Cobalt stent to treat narrowed iliac arteries

Advancing the treatment of peripheral artery disease, Medtronic, Inc. today announced approval by the U.S. Food and Drug Administration (FDA) of the Assurant Cobalt Iliac Balloon-Expandable Stent System.

From Medtronic 1 Nov 2011

FDA's Circulatory System Devices Panel unanimously recommends Cook Medical's Zilver PTX Drug-Eluting Stent

The Zilver PTX Drug-Eluting Stent, the first device of its kind developed to treat peripheral artery disease (PAD) in the superficial femoral artery (SFA), has received a unanimous recommendation from the Food and Drug Administration's (FDA) Circulatory System Devices Panel of the Medical Devices Advisory Committee, Cook Medical announced today.

14 Oct 2011

Engager Transcatheter Aortic Valve Implantation System pivotal trial to be conducted at 11 European centers

Medtronic, Inc. today announced the start of the Engager European Pivotal Trial to pursue CE Mark for the Engager Transcatheter Aortic Valve Implantation System in patients suffering from severe aortic stenosis.

From Medtronic 28 Sep 2011

Boston Scientific introduces Coyote Balloon Catheter for peripheral angioplasty

Boston Scientific Corporation has launched its Coyote Balloon Catheter, a highly deliverable and ultra-low profile 0.014 inch balloon dilatation catheter designed to treat patients undergoing peripheral angioplasty procedures below the knee. The Company has begun marketing the product in the U.S., Europe and other international markets.

19 Sep 2011

Patients with coronary artery disease more likely to have complications from orthopedic surgery

Thrombotic and bleeding events are complications that may occur after surgery. With the aging population in the western world, there are more patients undergoing orthopedic surgery than ever before. This makes understanding the risk of complications from orthopedic surgery exceedingly important. However, there is a lack of data investigating the incidence of thrombotic and bleeding complications in orthopedic surgery.

31 Aug 2011

Specific inhibitor of microRNA-100 can stimulate development of new blood vessels

A specific inhibitor of the small regulatory RNA-molecule "microRNA-100" can be used to stimulate the growth of new blood vessels, if a major artery is chronically occluded.

29 Aug 2011

New ESC Guidelines on diagnosis and treatment of peripheral artery disease

For cardiologists, coronary artery disease is the most important presentation of atherosclerosis. Patients with coronary artery disease may also have symptomatic or asymptomatic atherosclerosis in other vascular areas (peripheral artery disease).

26 Aug 2011