Peripheral Artery Disease News and Research

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Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. These blockages can result in severe pain for patients, limited physical mobility, and life-threatening non-healing leg ulcers. According to the American Heart Association, this condition affects approximately 8 to 12 million Americans. With only about 25 percent of PAD patients undergoing treatment, it is a disease that is largely under-diagnosed and under-treated. If left untreated, PAD can lead to critical leg ischemia, a condition where not enough blood is being delivered to the leg to keep the tissue alive. Total loss of circulation to the legs and feet can cause gangrene and lead to amputation.

Medicaid expansion related to better access to surgery and higher quality of care

The Affordable Care Act's Medicaid expansion was linked to better access to surgery and higher quality surgical care, according to a new study from Harvard T.H. Chan School of Public Health.

24 Jan 2018

Substituting animal proteins with plant proteins could reduce main cholesterol markers, study suggests

Substituting one to two servings of animal proteins with plant proteins every day could lead to a small reduction in the three main cholesterol markers for cardiovascular disease prevention, a new study suggests.

21 Dec 2017

Researchers develop molecular beacon to find hypoxic spots in real time

Areas of hypoxia, or low oxygen in tissue, are hallmarks of fast-growing cancers and of blockages or narrowing in blood vessels, such as stroke or peripheral artery disease. University of Illinois researchers have developed a way to find hypoxic spots noninvasively in real time.

8 Dec 2017

Interim survey results indicate low levels of CVD risk awareness among people with type 2 diabetes

Today the International Diabetes Federation presented the interim results of the first ever multi-country online survey on CVD risk awareness and knowledge among people living with type 2 diabetes, indicating low levels of awareness and limited dialogue between patients and healthcare professionals.

From Novo Nordisk 8 Dec 2017

Stem cell therapy fails to improve walking ability in people with PAD

A stem cell therapy did not improve walking ability in people with peripheral artery disease, although exercise did lead to significant improvements, according to the results of a new Northwestern Medicine clinical trial.

15 Nov 2017

PCSK9 inhibitor offers clinical benefit to patients with peripheral artery disease

Patients with peripheral artery disease (PAD) are at high risk of heart attack, stroke and cardiovascular death. In addition, PAD patients can suffer major adverse limb events, such as acute limb ischemia - the equivalent of a heart attack in the leg - that can lead to limb loss.

14 Nov 2017

Stem cells could help improve blood circulation in diabetic patients with peripheral artery disease

Stem cells taken from muscle tissue could promote better blood flow in patients with diabetes who develop peripheral artery disease, a painful complication that can require surgery or lead to amputation.

7 Nov 2017

ACIST Medical Systems announces debut of next generation FFR solution

ACIST Medical Systems, Inc., a Bracco Group Company, today announced the global launch of its ACIST RXi Mini System, the next generation system of its RXi Rapid Exchange FFR System. The RXi Mini System will debut at the 29th Transcatheter Cardiovascular Therapeutics scientific symposium in Denver, Colorado.

28 Oct 2017

Stem cell researchers make advance toward long-lasting blood vessel repair

Stem cell researchers at Emory University School of Medicine have made an advance toward having a long-lasting "repair caulk" for blood vessels. The research could form the basis of a treatment for peripheral artery disease, derived from a patient's own cells. Their results were recently published in the journal Circulation.

24 Oct 2017

Biomaterial-mediated growth factor delivery can restore perfusion of blood vessels in animal models

Ischemia is a serious medical condition in which the flow of blood and delivery of oxygen to tissues is restricted, thus resulting in pain, weakness, and more seriously, tissue and organ damage. Ischemia in muscle tissue, most commonly as a result of atherosclerosis, leads to life-threatening diseases like coronary artery disease and stroke, but also to chronic peripheral artery disease (PAD).

26 Sep 2017

Drug combination improves outcomes in patients with stable coronary or peripheral artery disease

Rivaroxaban plus aspirin improves survival and reduces stroke and heart attack in patients with stable coronary or peripheral artery disease, according to late-breaking results from the COMPASS trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in the NEJM.

28 Aug 2017

Drug combination superior in preventing further heart complications in people with vascular disease

A major international study has found that the combination of two drugs - rivaroxaban and aspirin -- is superior to aspirin alone in preventing further heart complications in people with vascular disease.

28 Aug 2017

ESC recommendations on management of patients with peripheral arterial diseases published

European Society of Cardiology Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, developed in collaboration with the European Society for Vascular Surgery (ESVS), are published online today in European Heart Journal, European Journal of Vascular and Endovascular Surgery, and the ESC website.

26 Aug 2017

Study shows how hyperglycemia following surgery for PAD affects post-surgical outcomes

High blood sugar, also known as hyperglycemia, occurs when the body does not produce enough insulin to turn blood glucose into energy.

31 May 2017

Findings highlight need to improve quality of care for high-risk patients with peripheral artery disease

Less than half of individuals with peripheral artery disease, which is a narrowing of arteries to the limbs, stomach and head, are treated with appropriate medications and lifestyle counseling. These findings highlight the need to improve the quality of care for this high-risk group of individuals.

3 May 2017

Knocking out lipid-modifying enzyme can boost post-heart attack healing, study shows

Two immune responses are important for recovery after a heart attack -; an acute inflammatory response that attracts leukocyte immune cells to remove dead tissue, followed by a resolving response that allows healing.

2 May 2017

Study reveals brain activity may be key to link between stress and heart disease

Increased activity in a deep-lying region of the brain called the amygdala is associated with a higher risk of heart attack and stroke, according to a study published in The Lancet. The amygdala is known to process emotions such as fear and anger and the finding sheds light on the possible mechanism by which stress can lead to cardiovascular disease (CVD), say the study authors.

12 Jan 2017

Hospitals eliminate bedsore occurrence using early detection technology

Using technology adapted from NASA's Mars lander as part of a large-scale bedsore reduction program, over half of the 13 participating hospitals were able to eliminate the occurrence of new bedsores completely; an additional 3 hospitals achieved reductions ranging from 11% to 90%.

23 Dec 2016

OrbusNeich launches new Dual Therapy Stent for active vessel healing

OrbusNeich has announced the launch of its latest generation Dual Therapy Stent (DTS), the COMBO Plus.

21 Nov 2016

New guidelines recommend use of antiplatelet therapy and exercise program for treatment of PAD

New guidelines for the treatment of peripheral artery disease (PAD), include recommendations on the use of antiplatelet therapy to reduce the risk of blood clots and statin drugs to lower cholesterol and advise PAD patients to participate in a structured exercise program.

13 Nov 2016