Phagocytes News and Research

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Comprehensive gene activity database could significantly reduce animal use

A comprehensive database of gene activity in mice across ten disease models, which could significantly reduce animal use worldwide, has been developed by scientists at the Francis Crick Institute, which gives a full picture of the immune response to different pathogens.

29 Jun 2019

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

Developed by researchers at the University of Turku in Finland, an immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumors in several mouse models.

20 Feb 2019

Researchers create new map of the brain's own immune system

A team of researchers under the direction of the Medical Center - University of Freiburg has created an entirely new map of the brain's own immune system in humans and mice.

19 Feb 2019

Neuropeptide Y may hold key to exacerbating severe influenza

Severe influenza virus infection is characterized by a strong inflammatory response and profuse viral replication in lungs. These viruses, such as the notorious avian flu, have a high rate of death and to date there are no effective treatments.

10 Jan 2019

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Lysosomes are filled with more than 50 different hydrolytic enzymes, which are capable of digesting most cellular components.

23 Dec 2018

Microglia show distinct responses under inflammatory conditions

The NorLux Neuro-Oncology Laboratory at LIH's Department of Oncology conducts research on brain diseases, with a special emphasis on glioma biology, drug resistance and systems approaches.

26 Nov 2018

Scientists succeed in increasing stability, biocompatibility of light-transducing nanoparticles

A team of scientists from the Helmholtz-Zentrum Dresden-Rossendorf, in collaboration with researchers from Monash University Australia, has succeeded in significantly increasing the stability and biocompatibility of special light-transducing nanoparticles.

13 Nov 2018

Neurons play active role in triggering a defense mechanism that leads to their own damage

Rasmussen's encephalitis is a rare autoimmune disease that primarily affects children and can lead to seizures.

31 Aug 2018

Modified T lymphocytes prevent nerve cell damage in encephalitis

Scientists have found a way to prevent neuron death in Rasmussen’s encephalitis, by exploiting T lymphocytes in the immune system.

30 Aug 2018

Study findings may lead to new approaches for treating inflammatory diseases

In the body, the immune system often begins its response to various attackers in the same way: the body activates immune cells, so-called phagocytes, which migrate to sites of inflammation caused by, for example, foreign pathogens or damaged tissue.

6 Jun 2018

Researchers develop new method to study activity of inflammatory cells

The process that the body sets in motion in the event of inflammation is complex, but also impressive. The main role here is played by immune cells migrating from the blood into the tissue to fight the inflammation.

17 Apr 2018

New study shows how the immune system regulates gut fungal population

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

11 Jan 2018

Study elucidates how lymphocytes regulate immune response after heart attacks

The damage caused by a heart attack triggers an inflammatory reaction which degrades the affected tissue. This response is orchestrated by immune cells that reside in the nearby pericardial adipose tissue, as a study by a team of Ludwig-Maximilians-Universitaet) in Munich shows.

30 Nov 2017

Process of removing cellular debris can fuel tumor growth in metastatic prostate cancer

The goal of any cancer treatment is to kill tumor cells. Yet, one little understood paradox of certain cancers is that the body's natural process for removing dead and dying cells can actually fuel tumor growth.

28 Nov 2017

Statin use linked to reduced risk of S aureus bloodstream infection

Users of statins, widely prescribed for prevention of cardiac disease, have a 27% lower risk of contracting a Staphylococcus aureus (S aureus) bloodstream infection outside of a hospital, according to a new study in Mayo Clinic Proceedings.

3 Oct 2017

New profiling procedure reveals role of immunoresolvents in blood coagulation

Stopping a wound from bleeding is essential for human health. Blood coagulation - in which blood goes from liquid to gel and forms a clot - can prevent excessive bleeding and infection. But exactly what molecular events transpire when blood coagulates has remained somewhat mysterious.

4 Aug 2017

Phagocytes News and Research

Comprehensive gene activity database could significantly reduce animal use

Immunotherapeutic antibody therapy to kill cancer has now progressed to patient testing

Researchers create new map of the brain's own immune system

Neuropeptide Y may hold key to exacerbating severe influenza

Study reveals how molecular mechanisms regulate lysosomal exocytosis by phagocytes

Microglia show distinct responses under inflammatory conditions

Scientists succeed in increasing stability, biocompatibility of light-transducing nanoparticles

Neurons play active role in triggering a defense mechanism that leads to their own damage

Modified T lymphocytes prevent nerve cell damage in encephalitis

Study findings may lead to new approaches for treating inflammatory diseases

Researchers develop new method to study activity of inflammatory cells

New study shows how the immune system regulates gut fungal population

Study elucidates how lymphocytes regulate immune response after heart attacks

Process of removing cellular debris can fuel tumor growth in metastatic prostate cancer

Statin use linked to reduced risk of S aureus bloodstream infection

New profiling procedure reveals role of immunoresolvents in blood coagulation

New approach may improve translation of immunological research findings

Mayo Clinic scientists develop novel nanoparticle to shrink tumors, prevent breast cancer recurrence

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Essen Bioscience to Showcase IncuCyte® Live-cell Analysis System and Applications at AACR, Booth #1365

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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