Pharmacoepidemiology News and Research

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The science of pharmacoepidemiology can answer a range of questions regarding how, why, when, where, and by whom a medicine is being used. It is a way of finding out the impact of a medicine as well as the usage results in a large, well-defined population. Also, it can help provide some indication as to how a particular drug is benefitting society and how it may be having a negative impact. Pharmacoepidemiology can be carried out both before and after a medicine is taken to market.

Indoor air pollution from cooking fuels linked to developmental delays in children

Just about everyone knows that cigarette smoke is bad for babies. Should cooking fuels like natural gas, propane and wood be viewed similarly when used indoors?

26 Sep 2023

Amoxicillin vs. amoxicillin-clavulanate: Which is more effective for acute sinusitis in children?

Brigham researchers found that patients prescribed amoxicillin-clavulanate had higher rates of gastrointestinal symptoms and yeast infections than those prescribed amoxicillin.

19 Sep 2023

Men and women with elevated blood sugar levels have greater risk of cardiovascular diseases

Men and women with raised blood sugar levels have 30-50% greater risk of developing cardiovascular diseases even when these levels are below the threshold for diabetes, a new study has shown.

10 Aug 2023

Many top-selling brand-name drugs in Medicare may provide little added therapeutic benefit

Brand-name drugs cost two to three times more in the U.S. than in other countries, but many of the top-selling brand name drugs may provide little added therapeutic benefit.

18 Apr 2023

Serious pneumococcal infection increases the risk of a heart attack significantly

After the onset of serious pneumococcal infections, patients are at a significantly increased risk of having a heart attack, according to a Vanderbilt study published in the journal Clinical Infectious Diseases.

2 Mar 2023

£1.7m NIHR funding to explore how routinely-collected healthcare data can be used to improve clinical guidance

Professor Laurie Tomlinson has been awarded a National Institute for Healthcare Research (NIHR) Research Professorship worth £1.7m to explore how routinely-collected healthcare data can be used to improve clinical guidance.

23 Feb 2023

Study examines postpartum women's experiences during the third wave of COVID-19

In a recent study published in the journal Pharmacoepidemiology, researchers investigated postpartum women’s birth-associated experiences during the third wave of the coronavirus disease 2019 (COVID-19) pandemic in Europe.

7 Feb 2023

Young people treated for sleep disorders with benzodiazepines may be at higher risk of overdose

Teens and young adults who are treated for sleep disorders with benzodiazepines such as Xanax – a medication commonly prescribed to treat anxiety and insomnia – may be at a higher risk of overdose, according to Rutgers researchers.

23 Nov 2022

Newer class of antidiabetic drugs reduced risk of hospitalization for heart failure

In cardiovascular outcome trials among adults with type 2 diabetes (T2D), sodium-glucose co-transporter 2 inhibitors (SGLT-2i) have shown therapeutic promise, including reduced risk of hospitalization for heart failure compared to placebo.

1 Jun 2022

Parallel approach to vaccine trials can lead to faster and more accurate assessment

Some of Rutgers' top health researchers are calling for a change in our approach to developing COVID-19 vaccines, and vaccines to fight future pandemics, to incorporate both conventional and challenge trails.

12 Apr 2022

Risk for anaphylaxis higher with two intravenous iron formulations

Two products commonly administered intravenously to replenish iron levels in the body have a much higher chance of provoking a severe allergic attack, according to Rutgers researchers who conducted a study analyzing the medical records in a large database of older, Medicare patients.

29 Mar 2022

Youth with intentional BZD overdoses more likely to have recent doctor-written prescription

A high number of teens and young adults with an overdose involving a benzodiazepine (BZD), like Xanax, or psychostimulant, like Adderall – medications commonly used to treat mental health issues like attention deficit hyperactivity disorder and anxiety disorders – have a recent medical prescription for a BZD or stimulant, according to Rutgers researchers who say physicians need to weigh the risks and benefits of these medications more closely.

10 Mar 2022

New findings support the routine use of remdesivir in hospitalized COVID-19 patients

Remdesivir, an antiviral drug used to treat COVID-19, increased the likelihood of clinical improvement in COVID-19 patients on low-flow oxygen or no oxygen, according to a new study authored by the Johns Hopkins University School of Medicine, the Johns Hopkins Bloomberg School of Public Health, HCA Healthcare, and Genospace.

18 Jan 2022

LSHTM joins with YouTube and Klick Health to create 'Community Unity' for tackling vaccine misinformation

The Vaccine Confidence Project (VCP) at the London School of Hygiene & Tropical Medicine has teamed up with YouTube and Klick Health to create 'Community Unity', a unique video series to help combat vaccine misinformation.

23 Nov 2021

LSHTM expert comments on NICE approval of first long-acting injectable HIV treatment

NHS watch-dog, the National Institute for Health and Care Excellence (NICE), has published guidance recommending the use of the first long-acting injectable treatment for HIV-1.

18 Nov 2021

UMass Amherst and Brigham launch MassAITC to improve in-home care for Alzheimer's patients

The University of Massachusetts Amherst and Brigham and Women's Hospital announced today the launch of the new Massachusetts AI and Technology Center for Connected Care in Aging and Alzheimer's Disease (MassAITC), which seeks to improve in-home care for older adults and individuals with Alzheimer's disease, thanks to a grant from the National Institute on Aging (NIA), which is part of the National Institutes of Health.

1 Nov 2021

New shorter treatment regimen found to be safer, more effective at treating drug-resistant TB

A new all-oral six-month treatment regimen is safer and more effective at treating rifampicin-resistant tuberculosis (RR-TB) than the current accepted standard of care, according to results announced at the 52nd Union World Conference on Lung Health.

20 Oct 2021

Additional health care support needed to improve medication adherence among people with hypertension

People with hypertension, or high blood pressure, play a key role in whether they use medication appropriately to manage their blood pressure.

7 Oct 2021

Rutgers and NYU secure $11.6 million to establish new Center for Asian Health Promotion and Equity

Rutgers Institute for Health, Health Care Policy and Aging Research, in close collaboration with New York University, has received $11.6 million in funding from the National Institute on Minority Health and Health Disparities to develop the Rutgers-NYU Center for Asian Health Promotion and Equity.

5 Oct 2021

COVID-19 Vaccine DSMB can serve as model for future situations

Clinical evaluation of three COVID-19 vaccine candidates in 2020-21 during a worldwide pandemic that killed or sickened millions was unprecedented in terms of urgency and scope.

16 Jun 2021