Phenotype News and Research

RSS

New DNA Microscopy Technique Offers Novel Insight into Genomic Information in Cells

Scientists are now able to see inside cells to a genomic level with a newly invented imaging technique called DNA microscopy. Using DNA “bar codes”, DNA microscopy allows scientists to locate a molecule’s position in a sample without using any kind of optics, meaning genomic information can be collected in large amounts.

21 Jun 2019

Adequate protein intake linked with reduced risk of frailty

Adequate intake of protein is associated with a reduced risk of frailty and prefrailty in older women, according to a new study from the University of Eastern Finland and Kuopio University Hospital. Adequate protein intake was defined as at least 1.1 g per kg of body weight. The findings were published in European Journal of Nutrition.

19 Jun 2019

Disease-modifying therapy for Alport syndrome still remains an unmet need

Alport syndrome is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure.

13 Jun 2019

New therapeutic approach utilizes endogenous processes to enhance cardiac repair

Myocardial infarction results in the localized death of the muscle cells that are essential for the heart's pumping function.

12 Jun 2019

Learned avoidance behavior can be inherited for multiple generations, say Princeton researchers

Princeton University researchers have discovered that learned behaviors can be inherited for multiple generations in C. elegans, transmitted from parent to progeny via eggs and sperm cells.

7 Jun 2019

Blink and you miss it: Imaging single cells travelling at the speed of Usain Bolt

A new review has summarized recent research into the development of ultra-high-throughput single cell analysis and multi-parametric imaging tools.

6 Jun 2019

Scientists highlight advances and uses of organoids in gastroenterology and hepatology

One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo.

4 Jun 2019

New tool reveals how genes interact to form tissues and organisms

Although the knowledge we have about human cells and tissues has steadily increased over recent decades, many things remain unknown.

4 Jun 2019

Study searches for the origins of depressive symptoms in Huntington's disease

About 40% of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

About 40 % of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

New repository enables easy exchange of machine learning models for genome research

Although the importance of machine learning methods in genome research has grown steadily in recent years, researchers have often had to resort to using obsolete software.

30 May 2019

Study identifies patterns of chronic lymphocytic leukemia growth

In patients with chronic lymphocytic leukemia, the rate of disease growth is apt to follow one of three trajectories: relentlessly upward, steadily level, or something in between, scientists at Dana-Farber Cancer Institute, the Broad Institute of MIT and Harvard, Massachusetts General Hospital, and the University of Washington report in a new study.

29 May 2019

Are DNA-based diets and personalized 'medical foods' the future for weight loss?

Experts say that by understanding how a person responds to specific nutrients, healthcare practitioners could provide better nutritional advice.

28 May 2019

UAB study reveals detrimental role of neutrophils in multiple sclerosis

Multiple sclerosis is an autoimmune disease that damages the insulating sheaths of nerve cells of the central nervous system. People with the disease can lose vision, suffer weak limbs, show degenerative symptoms and exhibit impaired cognition.

26 May 2019

Common genetic variant associated with increased food intake and weight gain

Researchers have discovered that children who do not have obesity, but who are at risk for the chronic disease due to a common genetic variant eat more, according to a new study to be published in the June 2019 issue of Obesity.

23 May 2019

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.

23 May 2019

Southern Research team aims to discover new, safer antimalarial medicines

Scientists at Southern Research's Drug Discovery division have joined the fight against malaria through efforts aimed at discovering new drugs and improving the safety and efficacy of current antimalarial medicines.

22 May 2019

Neonatal exposure to nicotine alters neurons, predisposes brain to addiction in adulthood

Neonatal exposure to nicotine alters the reward circuity in the brains of newborn mice, increasing their preference for the drug in later adulthood, report researchers at University of California San Diego School of Medicine in a study published "in press" April 24, 2019 in Biological Psychiatry.