Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

Real-time monitoring helps ease prosthetic leg pain

University of Washington engineers aim to ease this discomfort with research that could help build better sockets. They have developed a device that tracks how much a person's limb swells and shrinks when inside a prosthetic socket. The data could help doctors and patients predict how and when their limbs will swell, which could be used to build smarter sockets.

25 Jul 2013

GW professor receives $747,000 grant to research causes of severe intellectual disability and autism

As part of a national focus to better understand child health and development, Chiara Manzini, Ph.D., assistant professor of pharmacology and physiology at the George Washington University School of Medicine and Health Sciences, was awarded a $747,000 grant to research the causes of severe intellectual disability and autism.

25 Jul 2013

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

A new stem cell-based approach to studying epilepsy has yielded a surprising discovery about what causes one form of the disease, and may help in the search for better medicines to treat all kinds of seizure disorders.

25 Jul 2013

New quantitative screening method for diagnosing and longitudinal tracking of autism in children

Researchers at Indiana University School of Medicine and Rutgers University have developed a new quantitative screening method for diagnosing and longitudinal tracking of autism in children after age 3.

25 Jul 2013

Research: Arg-Phe-amide-related peptides may be important regulators of reproductive axis

During the last decade, our understanding of this hypothalamus-pituitary-gonadal axis has quickly expanded.

22 Jul 2013

Resveratrol counteracts exercise benefits in older men

In older men, a natural antioxidant compound found in red grapes and other plants -- called resveratrol -- blocks many of the cardiovascular benefits of exercise, according to research published today [22 July 2013] in The Journal of Physiology.

22 Jul 2013

Gladstone-led study finds underlying mechanisms behind Huntington's disease

Alzheimer's, Huntington's, Parkinson's. Names forever linked to what they represent: diseases that ravage the brain's neurons and leave entire regions to wither and die. These and other so-called neurodegenerative diseases are often associated with the buildup of toxic proteins that lead to the death of neurons.

22 Jul 2013

New research project has potential to treat human deafness and loss of balance

The sounds of success are ringing at Kansas State University through a research project that has potential to treat human deafness and loss of balance.

20 Jul 2013

Alcohol consumption during pregnancy has detrimental effects on fetal central nervous development

Maternal alcohol consumption during pregnancy has detrimental effects on fetal central nervous system development. Maternal alcohol consumption prior to and during pregnancy significantly affects cognitive functions in offspring, which may be related to changes in cyclin-dependent kinase 5 because it is associated with modulation of synaptic plasticity and impaired learning and memory.

20 Jul 2013

Scientists take important step toward pharmacologic development of treatment for fatal brain disorders

A team of researchers from Case Western Reserve University School of Medicine have identified a mechanism that can prevent the normal prion protein from changing its molecular shape into the abnormal form responsible for neurodegenerative diseases. This finding, published in the July 18 issue of Cell Reports, offers new hope in the battle against a foe that until now has always proved fatal.

19 Jul 2013

HemoShear announces milestone in development of predictive drug safety systems

HemoShear, LLC, a leading developer of human-relevant systems for drug development and discovery, today announced an important milestone in the development of systems that predict safety of new drugs and chemicals.

19 Jul 2013

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Scientists at the University of Massachusetts Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment.

18 Jul 2013

Both milky spots and fat cells in omentum promote ovarian cancer metastases

Cancer researchers have wondered why ovarian cancer cells are so attracted to the abdominal cavity, especially the omentum, with the hope that such an understanding could lead to better disease management or even prevention.

18 Jul 2013

Children exposed to AEDs in womb at risk of early development issues: Study

Children whose mothers took antiepileptic drugs while pregnant are at increased risk of early development issues, according to a new study published in Epilepsia, a journal published by Wiley on behalf of the International League Against Epilepsy.

18 Jul 2013

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

We classified ‘long-term’ cannabis use as being regular, at least weekly, cannabis use for over 12 months. This is the period of time that’s used in the DSM-IV psychiatric diagnostic manual to classify substance use disorders. In our study the average duration of at least weekly use was just over four and a half years.

17 Jul 2013

Research couple receives 2013 Khalid Iqbal Lifetime Achievement Award for Alzheimer's study

The research couple receives the "2013 Khalid Iqbal Lifetime Achievement Award" for its role as pioneers in investigating the role of tau in Alzheimer's disease. The award ceremony was held yesterday (10:45 am US EST) within the framework of the "Alzheimer's Association International Conference (AAIC 2013)" in Boston (USA).

17 Jul 2013

Standardized vascular health checks may improve health and cost-effectiveness outcomes

Archimedes Inc., a healthcare modeling company, today announced the results of a two-year long collaboration with Novo Nordisk A/S, a world leader in diabetes care, which evaluated the effects of standardized vascular health checks on expected health outcomes.

17 Jul 2013

Drug to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy

A drug already approved to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy, or thickening of the cardiac muscle--a disorder that often leads to heart failure, researchers at the University of Illinois at Chicago College of Medicine report.

17 Jul 2013

Study explores mechanisms of chemotherapy-induced neurological side effects

Chemotherapy is one of the primary treatments for cancer. However, one of the most disturbing findings of recent studies of cancer survivors is the apparent prevalence of chemotherapy-associated adverse neurological effects, including vascular complications, seizures, mood disorders, cognitive dysfunctions, and peripheral neuropathies.

16 Jul 2013

Researchers uncover role of IKACh in pacemaker activity and heart rate regulation

Researchers have uncovered a previously unknown role for the acetylcholine-activated inward-rectifying potassium current (IKACh) in cardiac pacemaker activity and heart rate regulation, according to a study in The Journal of General Physiology.

16 Jul 2013

Physiology News and Research

Real-time monitoring helps ease prosthetic leg pain

GW professor receives $747,000 grant to research causes of severe intellectual disability and autism

Stem cell-based epilepsy approach may help in search for better medicines to treat seizure disorders

New quantitative screening method for diagnosing and longitudinal tracking of autism in children

Research: Arg-Phe-amide-related peptides may be important regulators of reproductive axis

Resveratrol counteracts exercise benefits in older men

Gladstone-led study finds underlying mechanisms behind Huntington's disease

New research project has potential to treat human deafness and loss of balance

Alcohol consumption during pregnancy has detrimental effects on fetal central nervous development

Scientists take important step toward pharmacologic development of treatment for fatal brain disorders

HemoShear announces milestone in development of predictive drug safety systems

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Both milky spots and fat cells in omentum promote ovarian cancer metastases

Children exposed to AEDs in womb at risk of early development issues: Study

Long-term cannabis use, dopamine and motivation: an interview with Dr Michael Bloomfield, Department of Medicine at Imperial

Research couple receives 2013 Khalid Iqbal Lifetime Achievement Award for Alzheimer's study

Standardized vascular health checks may improve health and cost-effectiveness outcomes

Drug to treat multiple sclerosis may also hold promise for treating cardiac hypertrophy

Study explores mechanisms of chemotherapy-induced neurological side effects

Researchers uncover role of IKACh in pacemaker activity and heart rate regulation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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