Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

FDA grants Fast Track designation for Curemark's CM-AT autism treatment

Curemark LLC, a drug research and development company focused on the treatment of neurological diseases, announced that its CM-AT autism treatment, now in Phase III clinical trials, has been designated as a Fast Track drug by the U.S. Food and Drug Administration (FDA).

22 Feb 2010

Alnylam Pharmaceuticals initiates ALN-RSV01 Phase IIb trial in adult lung transplant patients for RSV infection

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated a Phase IIb trial in adult lung transplant patients with ALN-RSV01, an RNAi therapeutic for the treatment of respiratory syncytial virus (RSV) infection. RSV infection in lung transplant patients represents an important unmet medical need; the condition is associated with significant morbidity, including the development of acute lung transplant rejection in 10% to 20% of infected patients.

22 Feb 2010

Cash-strapped school districts are making mistake by cutting music from K-12 curriculum: Neuroscientist

At an 11 a.m. press briefing, Saturday, Feb. 20, at the American Association for the Advancement of Science annual meeting, a Northwestern University neuroscientist will argue that music training has profound effects that shape the sensory system and should be a mainstay of K-12 education.

22 Feb 2010

Animal study shows calcineurin enzyme is critical for normal heart function

Scientists are reporting the first-ever data to show that the enzyme calcineurin is critical in controlling normal development and function of heart cells, and that loss of the protein leads to heart problems and death in genetically modified mice.

20 Feb 2010

Harboring NRF2 gene may increase probability of being an endurance athlete

A few minor variations in one gene may make a difference in athletic endurance, according to a new study from Physiological Genomics.

19 Feb 2010

PsychoGenics announces alliance with experimental neuropharmacology expert for specialized microdialysis services

PsychoGenics Inc. today announced the establishment of an exclusive alliance with Dr. Jan Kehr, an internationally recognized expert in experimental neuropharmacology, to provide specialized microdialysis services to complement PsychoGenics’ in vivo testing capabilities.

19 Feb 2010

Researchers use Life Technologies’ next-generation sequencing instruments for cancer research

Life Technologies Corporation today announced the publication of two key scientific papers that highlight the utility of next-generation sequencing instruments in better understanding disease and the genetic differences that cause diversity within and between human populations. The Applied Biosystems SOLiD™ System was used in both of these research studies.

19 Feb 2010

Two UCSF scientists selected for Potamkin Prize for their achievements in research on dementias

Two UCSF scientists have been selected for the American Academy of Neurology's prestigious Potamkin Prize, for their "outstanding achievements" in research on dementias.

19 Feb 2010

Blood transfusions based on single low hematocrit measurement questioned

A comparison study of nearly 1,900 patients published in Perfusion, a peer-reviewed academic journal, questions the long-standing practice of basing blood transfusion decisions on a single low hematocrit measurement result. In the study, titled Is it the Patient or the Physician who Cannot Tolerate Anemia?, researchers showed that a single measure of hematocrit is not a reliable indicator of transfusion need and that lower-than-normal hemoglobin levels have no adverse impact on patients.

19 Feb 2010

FDA accepts filing of Jazz Pharmaceuticals' NDA for sodium oxybate

Jazz Pharmaceuticals, Inc. announced that the U.S. Food and Drug Administration has accepted for filing the New Drug Application (NDA) for JZP-6 (sodium oxybate) for the treatment of fibromyalgia.

19 Feb 2010

Single microRNA exhibits potential to forecast outcomes of MPM

Rosetta Genomics, Ltd., a leading developer and provider of microRNA-based molecular diagnostics, announced today that the results of a joint study with the NYU Langone Medical Center were published online on February 16th, 2010, and are set to be published in the March 1st issue of the American Association for Cancer Research’s journal, Cancer Research.

18 Feb 2010

New research units established for Japanese-German research collaboration

With its ten new Research Units, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is intensifying interdisciplinary and multiple-location collaboration among researchers pursuing specific scientific questions and new avenues of research.

17 Feb 2010

Researchers discover new strategy to overcome drug resistance in breast cancer

Combining tamoxifen, the world's most prescribed breast cancer agent, with a compound found in the flowering plant feverfew may prevent initial or future resistance to the drug, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

17 Feb 2010

New foundational research may advance pharmacological therapies for neurological disorders

Investigators in the Hotchkiss Brain Institute, Faculty of Medicine, have made a major breakthrough in our understanding of nerve impulse generation within the brain.

17 Feb 2010

New finding holds promise for rehabilitating patients after neurological damage

Harnessing brain signals to control keyboards, robots or prosthetic devices is an active area of medical research. Now a rare peek at a human brain hooked up to a computer shows that the two can adapt to each other quickly, and possibly to the brain's benefit.

16 Feb 2010

New research finds sensory cortex develops late in fragile X syndrome defect

Why do people with fragile X syndrome, a genetic defect that is the best-known cause of autism and inherited mental retardation, recoil from hugs and physical touch - even from their parents?

12 Feb 2010

Chemical compound found in blood shows promise in preventing intractable form of heart failure

A chemical compound found normally in the blood has shown promise in treating and preventing an intractable form of heart failure in a mouse model of the disease, report researchers at the University of Illinois at Chicago College of Medicine.

11 Feb 2010

BBSRC commits £15M to establish training for food security research and development

The Biotechnology and Biological Sciences Research Council (BBSRC) is today (10 Feb 2010) committing up to £15M to establish training for food security research and development.

11 Feb 2010

Journal explores biological and environmental challenges in elite winter sports

As the world turns its sporting gaze towards Vancouver for the 2010 Winter Olympics, The Physiological Society journal Experimental Physiology marks the occasion with a special issue exploring the biological and environmental challenges elite winter athletes must overcome to win gold.

11 Feb 2010

UH researchers create Walk n' Play iPhone application to keep track of physical activity

An iPhone application created by UH researchers is providing first-of-its-kind real-time statistics of physical activity around the world. Those annual rankings of America's fattest and fittest cities that use government statistics and a host of indirect indicators may soon have a little more muscle. The information being collected at the University of Houston provides objective data.

10 Feb 2010

Physiology News and Research

FDA grants Fast Track designation for Curemark's CM-AT autism treatment

Alnylam Pharmaceuticals initiates ALN-RSV01 Phase IIb trial in adult lung transplant patients for RSV infection

Cash-strapped school districts are making mistake by cutting music from K-12 curriculum: Neuroscientist

Animal study shows calcineurin enzyme is critical for normal heart function

Harboring NRF2 gene may increase probability of being an endurance athlete

PsychoGenics announces alliance with experimental neuropharmacology expert for specialized microdialysis services

Researchers use Life Technologies’ next-generation sequencing instruments for cancer research

Two UCSF scientists selected for Potamkin Prize for their achievements in research on dementias

Blood transfusions based on single low hematocrit measurement questioned

FDA accepts filing of Jazz Pharmaceuticals' NDA for sodium oxybate

Single microRNA exhibits potential to forecast outcomes of MPM

New research units established for Japanese-German research collaboration

Researchers discover new strategy to overcome drug resistance in breast cancer

New foundational research may advance pharmacological therapies for neurological disorders

New finding holds promise for rehabilitating patients after neurological damage

New research finds sensory cortex develops late in fragile X syndrome defect

Chemical compound found in blood shows promise in preventing intractable form of heart failure

BBSRC commits £15M to establish training for food security research and development

Journal explores biological and environmental challenges in elite winter sports

UH researchers create Walk n' Play iPhone application to keep track of physical activity

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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