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Clinical trial shows promising results for oral psoriasis treatment

A company launched from The University of Queensland's Institute for Molecular Bioscience (IMB) has passed an important milestone in developing an oral treatment for the common skin disease psoriasis.

15 Mar 2023

Hunger hormone can increase the heart's pump capacity in patients with heart failure

A clinical study by researchers at Karolinska Institutet and Karolinska University Hospital in Sweden shows that the hunger hormone ghrelin can increase the heart's pump capacity in patients with heart failure.

14 Mar 2023

Cholesterol-lowering drugs show potential to reduce heart disease in sleep apnea patients

A new study by Columbia University researchers suggests that cholesterol-lowering drugs called statins have the potential to reduce heart disease in people with obstructive sleep apnea regardless of the use of CPAP machines during the night.

13 Mar 2023

Injectable peptide used for type 2 diabetes shows potential for treating 'blinding' IIH headaches

Patients with 'blinding' headaches known as Idiopathic Intercranial Hypertension could be treated with an injectable peptide used for type 2 diabetes, a new trial has found.

13 Mar 2023

What is the effect of low Anti-Müllerian hormone on semen quality?

A recent BMC Medicine study investigated the relationship between Vitamin D and serum Anti-Müllerian hormone (AMH) in infertile men. This study was based on secondary analysis of a randomized clinical trial, which assessed the effect of high-dose Vitamin D plus calcium and placebo on semen quality in Vitamin D deficient infertile men.

10 Mar 2023

Examining the effect of hormone replacement therapy on postmenopausal heart disease and cognitive decline

Many are aware of the short-term symptoms often associated with menopause, such as hot flashes, which are attributed to changes in reproductive hormones.

9 Mar 2023

Nirogacestat shows promising results in patients with desmoid tumors

When Dana Avellino, now 36, first noticed a lump near her groin in the summer of 2018, she thought it was related her recent cesarean section. Her younger daughter was only 2 months old at the time.

9 Mar 2023

Natural by-product of olive oil production could support exercise

New research has found that a natural by-product of olive oil production could potentially have antioxidant benefits and support exercise.

9 Mar 2023

Early outpatient treatment of COVID-19 with metformin could reduce the risk of developing long COVID

In a recent study posted to Preprints with The Lancet*, a team of researchers from the United States investigated whether early outpatient treatment of coronavirus disease 2019 (COVID-19) patients with fluvoxamine, ivermectin, or metformin could prevent long coronavirus disease (long COVID).

9 Mar 2023

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody.

8 Mar 2023

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

MK-0616, an experimental oral proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, met its primary endpoint and substantially reduced levels of low-density lipoprotein (LDL) cholesterol in people with high cholesterol and/or heart disease related to clogged arteries, in a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Addition of sotatercept to existing therapy shows promise for the treatment of pulmonary arterial hypertension

Patients with pulmonary arterial hypertension (PAH), a severe, progressive condition that affects the heart and lungs, who were treated with the novel first-in-class medication sotatercept on top of existing therapy experienced significant improvements in walking distance via a six-minute walking test—the study's primary endpoint and a validated surrogate for functional improvement and reduced symptom burden.

6 Mar 2023

What is the impact of oral cannabidiol on simulated driving?

Researchers assessed the impact of cannabidiol on the driving performance of humans.

6 Mar 2023

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Researchers performed a meta-analysis analyzing randomized controlled trials (RCTs) that evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines, and the dose-response association of humoral responses with vaccine effectiveness.

6 Mar 2023

Clinical study reveals new use for high blood pressure drug in pediatric patients

A clinical study conducted by Indiana University School of Medicine researchers revealed that oral verapamil, a readily available and commonly used drug to treat high blood pressure and heart conditions, can also improve the pancreas' insulin secretion in children with newly-diagnosed type 1 diabetes (T1D).

1 Mar 2023

Taking vitamin D associated with living dementia-free for longer time

Taking vitamin D supplements may help ward off dementia, according to a new, large-scale study.

1 Mar 2023

Covid-19 vaccination can curb the effect of long COVID on patients' social, professional, and family lives

Vaccination against SARS-CoV-2, the virus responsible for COVID-19, may lessen the severity and duration of 'long COVID' in those with persistent symptoms after infection, suggests a study that closely imitates a randomized clinical trial, and published in the open access journal, BMJ Medicine.

1 Mar 2023

Placebo News and Research

Clinical trial shows promising results for oral psoriasis treatment

Hunger hormone can increase the heart's pump capacity in patients with heart failure

Cholesterol-lowering drugs show potential to reduce heart disease in sleep apnea patients

Injectable peptide used for type 2 diabetes shows potential for treating 'blinding' IIH headaches

What is the effect of low Anti-Müllerian hormone on semen quality?

Examining the effect of hormone replacement therapy on postmenopausal heart disease and cognitive decline

Nirogacestat shows promising results in patients with desmoid tumors

Natural by-product of olive oil production could support exercise

Early outpatient treatment of COVID-19 with metformin could reduce the risk of developing long COVID

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

Addition of sotatercept to existing therapy shows promise for the treatment of pulmonary arterial hypertension

What is the impact of oral cannabidiol on simulated driving?

Meta-analysis on COVID-19 vaccine effectiveness in association with antibody titers

Clinical study reveals new use for high blood pressure drug in pediatric patients

Taking vitamin D associated with living dementia-free for longer time

Covid-19 vaccination can curb the effect of long COVID on patients' social, professional, and family lives

Microglia may be the culprit behind concentration and memory problems after chemotherapy

High-dose ivermectin does not reduce COVID-19 symptom duration among mild-to-moderate outpatients

Rebounding of COVID-19 symptoms and viral load are common among untreated COVID-19 patients

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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