Placebo News and Research

RSS

Angina drug nifedipine safe for long-term use

Calcium antagonists such as nifedipine are used to relieve the symptoms of angina, but there have been doubts about their long-term safety. However, ACTION--A Coronary disease Trial Investigating Outcome with Nifedipine GITS--provides new information on the drug's long-term use. GITS (gastrointestinal therapeutic system) modifies the release of the drug to provide stable long-term concentrations of nifedipine in blood.

30 Aug 2004

Early use of aggressive statin therapy may offer some benefit for coronary patients

Statins initiated early after a patient experiences an acute coronary syndrome (ACS) event at dosages above the typical starting dose may help reduce subsequent cardiovascular events, but the high dose regimen used may increase the risk for muscle-related complications, according to the results from the Phase Z portion of the A to Z Trial released on the JAMA website today.

30 Aug 2004

The proper use of drugs to treat heart disease reduces the need for hospital interventions

Regular attacks of chest pain induced by exercise (angina pectoris) is a common condition caused by blockages of the blood vessels that supply the heart (coronary heart disease).

29 Aug 2004

New study confirms benefits of rimonabant in weight loss

Phase III clinical study comparing placebo to rimonabant, the first agent in a new therapeutic class known as selective cannabinoid type 1 (CB1) blockers, showed that overweight or obese people taking rimonabant 20mg once daily benefited from a significant reduction in their body weight

29 Aug 2004

Dronedarone is effective and well-tolerated in the prevention of atrial fibrillation

New anti-arrhythmic agent, dronedarone, is highly effective in the prevention of atrial fibrillation or atrial flutter recurrence, serious disorders of cardiac rhythm, and is well-tolerated by patients.

29 Aug 2004

Yogurt, unfortunately, is not the answer for thrush

The curative power of yogurt to prevent cases of thrush when taking antibiotics has been debunked by a University of Melbourne researcher.

27 Aug 2004

Statins (HMG-CoA reductase inhibitors), are effective long term

Statins (HMG-CoA reductase inhibitors), a class of drugs that block production of cholesterol in the liver, lower total cholesterol and LDL and are also associated with cardiovascular benefits, are effective in the long term, conclude authors of a study in this week’s issue of THE LANCET.

26 Aug 2004

Probiotics of no use for vaginal problems

"Friendly" bacteria (probiotics) are widely used and recommended for general health and specifically for vaginal problems.

26 Aug 2004

Are nicotine patches safe for pregnant women?

A £1 million study, being led by a team of multidisciplinary researchers at The University of Nottingham, is to look at whether nicotine replacement skin patches could help pregnant mums to stop smoking.

26 Aug 2004

Prozac helps treat adolescents with depression

The TADS researchers said that major depressive disorder is common, with one in 20 teens affected at varying levels of severity. Like other forms of depression, major depressive disorder has been associated with increased risk of suicidal behavior and with completed suicide.

26 Aug 2004

Pfizer receives approval for acute bipolar mania drug

Pfizer has announced that the U.S. Food and Drug Administration (FDA) has approved the use of its atypical antipsychotic Geodon(R) (ziprasidone HCI) for the treatment of acute bipolar mania including manic and mixed episodes.

23 Aug 2004

Effectiveness of gingko to treat early dementia

Researchers in London are to explore the effectiveness of gingko, a complementary medicine traditionally used to treat circulatory problems, as a treatment for early dementia.

23 Aug 2004

Pfizer drug effectively treats overactive bladder symptoms

Women with mixed incontinence, a combination of overactive bladder and stress incontinence, reported a greater treatment benefit for overactive bladder symptoms from DETROL® LA (tolterodine tartrate extended release capsules) than placebo, according to new study results published in the August issue of Urology.

21 Aug 2004

Nicotine replacement therapy shown to help teenagers and women

In the first study, researchers at the Stanford University School of Medicine have found that the nicotine patch seems to work as well, at least initially, for teens as it does for adults. In addition, the patch, the top delivery form of NRT (followed by gum, an inhaler and a nasal spray) worked equally well with or without supplementation by an anti-depressant given to the teens.

21 Aug 2004

Current information on the use of antidepressants in pediatric patients

The Food and Drug Administration has issued an update to provide health care providers and patients with the most current information on the use of antidepressants in pediatric patients.

21 Aug 2004

People with type 2 diabetes could benefit from atorvastatin

Results of a randomised trial in this week’s issue of THE LANCET suggest that people with type 2 diabetes could benefit from cholesterol-lowering therapy with statins to reduce the risk of cardiovascular disease, even when they do not have high cholesterol concentrations.

20 Aug 2004

Vitamin E has potential benefit in fighting colds in the elderly

Vitamin E supplementation has potential benefit in fighting upper respiratory tract infections such as colds in the elderly, says a study published in the Aug. 18 issue of JAMA.

18 Aug 2004

"Treatment for Adolescents with Depression Study" - a landmark study

The "Treatment for Adolescents with Depression Study" (TADS), reported in this week's Journal of the American Medical Association, is the first multi- center, randomized clinical effectiveness trial to review a combination of treatments for the types of adolescent depression likely to be treated in routine community-based practice settings.

18 Aug 2004

Treatment of child depression most successful with Prozac and cognitive-behavior therapy combination

A new study by researchers at the UT Southwestern Medical Center at Dallas, have found that treatment of child depression was most successful when a combination of Prozac and cognitive-behavior therapy was applied.

18 Aug 2004

Mixed effects for vitamin E against respiratory infections

Vitamin E does not appear to have a beneficial effect on lower respiratory tract infections in elderly nursing home residents, but it may help them ward off upper respiratory tract infections, according to a study in the current issue of the Journal of the American Medical Association.

18 Aug 2004