Placenta News and Research

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Genzyme begins gene transfer trial for peripheral arterial disease

Genzyme Corporation announced today that the first patient has been treated in a new phase 2 clinical trial examining the safety and effectiveness of locally delivered gene transfer for patients with peripheral arterial disease.

24 Feb 2005

Pollution exposure during pregnancy can cause chromosomal abnormalities in fetal tissues

A new study of newborns in New York City reveals that prenatal exposure to combustion-related urban air pollutants alters the structure of chromosomes (the carriers of genes) of babies in the womb.

23 Feb 2005

New technique to identify fetal genetic material from amniotic fluid

A preliminary report suggests that cell-free fetal messenger RNA (ribonucleic acid) can be extracted from amniotic fluid (fluid around the fetus), and then be analyzed to study gene expression changes that may reflect the well-being of the fetus, according to a paper in the February 16 issue of JAMA, a theme issue on medical applications of biotechnology.

15 Feb 2005

Exposure of expectant mothers to urban air pollution may alter the structure of babies' chromosomes while in the womb

A new study of 60 newborns in New York City reveals that exposure of expectant mothers to combustion-related urban air pollution may alter the structure of babies' chromosomes while in the womb.

15 Feb 2005

New way to assess the potentially damaging effects of prenatal drug exposure

Scientists have demonstrated a new way to assess the potentially damaging effects of prenatal drug exposure--a technique that could also be used to monitor a fetus's response to therapeutic drugs--using sophisticated, noninvasive medical imaging tools.

7 Feb 2005

Prenatal exposure to industrial and environmental pollutants probably causes most childhood cancers

Most childhood cancers are "probably" down to prenatal exposure to industrial and environmental pollutants, most likely to have been inhaled by the mother during pregnancy, suggests research in the Journal of Epidemiology and Community Health.

16 Jan 2005

A gallery of highly-specific, gene and protein “mug shots” of cancer types would be a powerful for oncologists

Doctors would like to diagnose malignancies rapidly by matching them with highly-specific genetic “mug shots” based on the presence of characteristic mRNAs or proteins. This kind of specificity would facilitate screening and early detection, and would potentially allow targeted treatments specific to each type of cancer

4 Dec 2004

Exposure to methamphetamine in the womb causes adverse developmental effects

International studies suggest that children exposed to methamphetamine in the womb are likely to suffer adverse developmental effects – either because of the drug, or the environment in which they are subsequently raised.

29 Nov 2004

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

A new study published in the New England Journal of Medicine confirms that stem cells derived from the umbilical cords of newborn babies are a viable and effective transplant source for thousands of leukemia patients who have no other treatment option.

24 Nov 2004

Scientists have found that a protein present in normal body tissues can prevent tumour growth

A team led by Dr Dave Bates, British Heart Foundation Lecturer, and Dr Steve Harper, Senior Research Fellow in the Microvascular Research Laboratories, in the Department of Physiology at Bristol University, have discovered that a type of vascular endothelial growth factor (VEGF) found in normal tissue, including blood, can prevent cancers from growing.

1 Nov 2004

Small delay after birth when cutting umbilical cord of a premature baby appears to lessen chances of bleeding

Waiting 30 seconds to two minutes after birth to cut the umbilical cord of a premature baby appears to lessen chances of bleeding in the newborn’s brain and reduce the need for transfusions, according to a new review of research.

18 Oct 2004

Genetic link to Preeclampsia, a serious complication of pregnancy

When a particular combination of proteins is expressed by a mother and her developing fetus, the risk of developing preeclampsia increases, according to a study by Hiby and colleagues in the Oct 18 issue of The Journal of Experimental Medicine.

11 Oct 2004

Outbreak of whooping cough in South Australia

South Australia's Department of Health is urging parents to make sure their children are immunised against whooping cough as an outbreak is beginning in SA.

28 Sep 2004

Studies of human genetic variation have found strong evidence for the action of natural selection

One of the most comprehensive studies of the forces that have shaped patterns of human genetic variation has found strong evidence for the action of natural selection, which may help explain why certain people are at risk for a variety of conditions and others are not.

8 Sep 2004

Lack of a gene called LBP-1a in the embryo prevents normal growth of blood vessels in the placenta

The lack of a gene called LBP-1a in the mouse embryo prevents normal growth of blood vessels in the placenta. This finding suggests that a similar defect in humans could play a role in fetal growth retardation, infant mortality and spontaneous abortion.

6 Aug 2004

Placenta News and Research

Genzyme begins gene transfer trial for peripheral arterial disease

Pollution exposure during pregnancy can cause chromosomal abnormalities in fetal tissues

New technique to identify fetal genetic material from amniotic fluid

Exposure of expectant mothers to urban air pollution may alter the structure of babies' chromosomes while in the womb

New way to assess the potentially damaging effects of prenatal drug exposure

Prenatal exposure to industrial and environmental pollutants probably causes most childhood cancers

A gallery of highly-specific, gene and protein “mug shots” of cancer types would be a powerful for oncologists

Exposure to methamphetamine in the womb causes adverse developmental effects

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

Scientists have found that a protein present in normal body tissues can prevent tumour growth

Small delay after birth when cutting umbilical cord of a premature baby appears to lessen chances of bleeding

Genetic link to Preeclampsia, a serious complication of pregnancy

Outbreak of whooping cough in South Australia

Studies of human genetic variation have found strong evidence for the action of natural selection

Lack of a gene called LBP-1a in the embryo prevents normal growth of blood vessels in the placenta

World’s first computer model of a pregnant crash dummy

New York study reveals that babies in the womb are more sensitive than their mothers to DNA damage from pollution

Newborns are more susceptible to DNA damage from pollution than their mothers

Exposure to excess hormones in the womb increases risk of heart disease and diabetes

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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