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Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

Researchers investigate the effect of sulfur water baths on rheological blood properties

Researchers evaluated the health benefits of sulfur balneotherapy (sulfur baths) on the rheological properties of the blood of osteoarthritis (OA) patients.

19 May 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023

Exploiting platelets for antitumor drug delivery and immune modulation of tumor microenvironment

Announcing a new publication for Acta Materia Medica journal. Platelets are blood components traditionally believed to have fundamental roles in vascular hemostasis and thrombosis.

15 May 2023

Evaluating the effect of resveratrol-enriched bread in preventing early type 2 diabetes cardiomyopathy in vivo

Researchers examined the effects of resveratrol-enriched bread on a diabetes model.

11 May 2023

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

Scientists discuss hantavirus infections, which are a type of viral hemorrhagic fever that can be transmitted to humans through exposure to infected rodents in endemic areas.

30 Apr 2023

Vein-on-a-chip model can help understand the mechanisms of blood clot formation

Blood clot researchers could benefit from a new device that mimics a human vein, replacing the need for animals for some studies.

27 Apr 2023

Researchers draw attention to the traps in clinical studies on osteoarthritis

Recruiting osteoarthritis patients with a lot of pain to clinical studies, may give incorrect results if the researcher does account for the natural variation in pain that occurs.

26 Apr 2023

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Researchers explored the pathophysiological variables and coagulation abnormalities associated with long coronavirus disease (COVID).

21 Apr 2023

Is there a correlation between acute and chronic red wine intake and health?

Researchers examined the correlations between acute and chronic red wine (RW) intake and health.

18 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Study highlights the potential long-term neurological effects post-COVID-19

Researchers studied the presence of the SARS-CoV-2 spike protein in the skull-meninges-brain (SMB) axis.

10 Apr 2023

Mediterranean diet and the modulation of mitochondrial function

Researchers reviewed the current knowledge related to the Mediterranean diet (MedDiet) and the role of mitochondria concerning health outcomes.

7 Apr 2023

Red blood cell hitch-hiking facilitates SARS-CoV-2 multi-organ spread

Researchers assessed the infectious capacity of severe acute respiratory syndrome coronavirus 2 in plasma and red blood cells.

3 Apr 2023

Black sea urchin extract shows promise in combating atherosclerosis

A team of Italian scientists has identified potential anti-inflammatory and vasculoprotective effects of red cell extracts of the Black Sea urchin Arbacia lixula. The study has been published in the journal Nutrients.

30 Mar 2023

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

In a recent study published in the journal PLoS ONE, researchers in Spain performed a systematic review of pneumolysin (PLY) toxin as a molecular target to develop novel therapeutics against Streptococcus pneumoniae.

27 Mar 2023

Researchers discover a new switching point that regulates hemostasis and thrombosis

The glycoprotein V of the blood platelets is an important switch point for hemostasis and thrombus formation. This new finding could have great clinical potential.

24 Mar 2023

Higher plasma caffeine concentrations might reduce body fat and type 2 diabetes risk

In a recent study published in the journal BMJ Medicine, researchers in the United Kingdom and Sweden investigated the probable causality of long-term serum caffeine concentrations on type 2 diabetes (T2D), adiposity, and major cardiovascular diseases (CVDs).

22 Mar 2023

Music-listening interventions can make medications more effective

While listening to a favorite song is a known mood booster, researchers at Michigan State University have discovered that music-listening interventions also can make medicines more effective.

21 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023