Polymerase News and Research

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Significant humoral immune evasion contributes to the emergence and rapid spread of Arg346-mutated BA.4 and BA.5 sublineages

=Researchers measured the neutralizing titers of plasma samples against the SARS-CoV-2 new variant of concern Omicron's sub-variants BA.4 and BA.5 with arginine (Arg)346 mutations.

29 Sep 2022

Blood test could predict people's likelihood of developing long Covid

A blood test taken at the time of Covid-19 infection could predict who is most likely to develop long Covid, suggests a new small-scale study led by UCL researchers.

28 Sep 2022

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

Researchers developed a high-throughput, rapid antigen SARS-CoV-2 spike protein detection test using allonamers, a new type of aptamers that carry out allosteric regulation instead of catalytic activity.

28 Sep 2022

Wastewater epidemiology can guide local clinical decisions on circulating viruses

The findings of a new study posted to the medRxiv* preprint server depicted that wastewater-based epidemiology (WBE) can provide information on the circulating respiratory viruses in a community. As well as saving time and money, this method may assist in appropriate clinical decision-making, behavior modification, and public health interventions.

28 Sep 2022

What is the association between air ventilation and pathogen transmission?

Researchers assessed the association between indoor air respiratory pathogens and natural ventilation, carbon dioxide (CO2) levels, and air filtration.

27 Sep 2022

Observing SARS-CoV-2 Omicron reinfections with different sub-variants

In a new study, researchers observed early recurrence of coronavirus disease 2019 (COVID-19).

27 Sep 2022

What is the vaccine efficacy of repeated influenza vaccinations?

In a new study, researchers calculated the decrease in vaccine effectiveness due to repeated influenza vaccinations.

27 Sep 2022

How do clinical outcomes in patients infected with different Omicron subvariants differ?

Researchers compare the clinical outcomes, upper respiratory viral loads, and viral recovery of different SARS-CoV-2 Omicron subvariants on cell cultures.

27 Sep 2022

Differences in protection from previous infection or vaccination against infection with Omicron BA.4/5 or BA.2

Researchers investigated the differences in vaccination- and previous infection-induced immunities against the Omicron BA.2 and BA.4/5 subvariants of SARS-CoV-2.

27 Sep 2022

What is the association between COVID-19 and type 1 diabetes?

In a new study, researchers assessed the relationship between incident type 1 diabetes and recent coronavirus disease 2019 (COVID-19) Infection.

27 Sep 2022

Association of self-reported chronic fatigue and retinal microcirculation in post-COVID-19 syndrome patients

Researchers investigated the potential association between self-reported chronic fatigue and retinal microcirculation among post-COVID-19 syndrome patients.

27 Sep 2022

Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cells models

In a recent study posted to the bioRxiv* preprint server, researchers in Australia explored the molecular mechanisms of the pulmonary and cardiac complications caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using human stem-cell-derived cardiac and lung cells.

27 Sep 2022

COVID-19 can cause long-term lung damage to children and teens

In a recent study published in the Radiology journal, researchers in Germany assessed the pulmonary dysfunction observed after pediatric coronavirus disease 2019 (COVID-19).

27 Sep 2022

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Recent studies have shown that patients with weakened immune systems—which enables the virus that causes COVID-19 to remain longer in the body, copy itself, and continually change—may enable the development of new, slightly different versions of the virus (variants).

26 Sep 2022

What is the association between body fat and COVID-19?

Researchers recently assessed the association between adipose tissues and COVID-19 by evaluating autopsy cases and profiling adipose tissue responses to SARS-CoV-2 infections.

26 Sep 2022

Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

In a recent study posted to the medRxiv* preprint server, researchers in the United States described the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), tested in PREVENT-19 — a phase 3, randomized, placebo-controlled, observer-blinded trial among 12- to 17-year-old adolescents in the United States (U.S).

25 Sep 2022

Study compares monkeypox PCR testing protocols and efficiency at two U.S. reference labs

In a recent study posted to the medRxiv* preprint server, researchers examined sample collection practices, epidemiological characteristics, and cycle threshold (Ct) values for polymerase chain reaction (PCR) tests used in two reference laboratories in the United States (U.S.) to detect monkeypox virus (MPXV).

25 Sep 2022

How smallpox and monkeypox viruses affect the nervous system

A recent study provides an overview of existing literature on the complications of infection with both smallpox and monkeypox virus.

25 Sep 2022

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC).

22 Sep 2022

Polymerase News and Research

Significant humoral immune evasion contributes to the emergence and rapid spread of Arg346-mutated BA.4 and BA.5 sublineages

Blood test could predict people's likelihood of developing long Covid

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

Wastewater epidemiology can guide local clinical decisions on circulating viruses

What is the association between air ventilation and pathogen transmission?

Observing SARS-CoV-2 Omicron reinfections with different sub-variants

What is the vaccine efficacy of repeated influenza vaccinations?

How do clinical outcomes in patients infected with different Omicron subvariants differ?

Differences in protection from previous infection or vaccination against infection with Omicron BA.4/5 or BA.2

What is the association between COVID-19 and type 1 diabetes?

Association of self-reported chronic fatigue and retinal microcirculation in post-COVID-19 syndrome patients

Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cells models

COVID-19 can cause long-term lung damage to children and teens

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

What is the association between body fat and COVID-19?

Common germline variants of APOE contribute to differential COVID-19 outcomes

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

Study compares monkeypox PCR testing protocols and efficiency at two U.S. reference labs

How smallpox and monkeypox viruses affect the nervous system

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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