Polymerase News and Research

RSS

How can we define early COVID-19 reinfections?

In a new study, researchers investigated coronavirus disease 2019 reinfections.

11 Jul 2022

Study reveals sex-based differences in the clinical outcomes of COVID-19 in the US

Researchers investigated sex-based differences among COVID-19 patients in the United States.

11 Jul 2022

SARS-CoV-2 spike protein downregulates ACE2 expression

In a new study, researchers observed the downregulation of ACE2 by SARS-CoV-2.

11 Jul 2022

Early detection of SARS-CoV-2 variants via wastewater sequencing uncovers cryptic transmission

In a recent study published in the Nature journal, researchers assessed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission using wastewater sequencing.

11 Jul 2022

Study highlights need to prioritize immunocompromised COVID patients

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers evaluated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected immunocompromised individuals are at a higher risk of intensive care unit (ICU) admission and death.

10 Jul 2022

The putative impact of vitamin D receptor gene polymorphisms on SARS-CoV-2 infection among different variants

Researchers assessed the association between SARS-CoV-2 variants and the vitamin D receptor gene.

8 Jul 2022

Immunogenicity and safety of the protein-based heterodimer booster vaccine for COVID-19

Researchers compared the immunogenicity and safety of the protein-based heterodimer vaccine (PHH-1V) and BNT162b2 COVID-19 vaccines.

8 Jul 2022

The strength and breadth of antibody responses elicited by hybrid immunity to COVID-19 vaccination or infection alone

Researchers assessed neutralizing antibody responses to SARS-CoV-2 after receiving one dose of vaccine.

8 Jul 2022

Discovery of multiple new SARS-CoV-2 MPro inhibitors

In a recent study posted to the bioRxiv* preprint server, researchers performed an extensive library docking for new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) covalent and non-covalent inhibitors.

8 Jul 2022

Asymptomatic monkeypox infection detected from routine sexual health samples

A new study reports on the incidence of subclinical monkeypox infection among individuals attending a sexual health clinic in Belgium.

7 Jul 2022

Study examines IMPACC trial results to understand clinical phenotypes of disease severity in hospitalized COVID-19 patients

In a recent article, longitudinal clinical phenotypes were described based on respiratory ordinal scales.

7 Jul 2022

2022 monkeypox presents with new symptoms

In a recent study published in The Lancet Infectious Diseases, researchers described the clinical and demographical characteristics of monkeypox virus infections among individuals attending sexual health centers in the United Kingdom (UK).

6 Jul 2022

The contamination of surfaces in hospital rooms housing monkeypox patients

Researchers investigated the contamination of surfaces in hospital rooms housing monkeypox patients.

6 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses.

6 Jul 2022

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

In a new study, researchers assessed the influence of severe coronavirus disease 2019 on scrotal infections.

5 Jul 2022

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

In a new study, researchers reported on the non-ACE2 blocking neutralizing antibodies elicited in response to severe coronavirus disease 2019 using deep ribonucleic acid sequencing with >100 million reads per sample and molecular dynamic simulations.

5 Jul 2022

Effectiveness of two and three doses of BNT162b2 against hospital and ED admissions for BA.1 and BA.2 infection

Researchers compared the effectiveness of two and three-dose regimens of COVID-19 vaccine BNT1262b against Omicron BA.1 and BA.2-related hospital and ED admissions.

5 Jul 2022

The varying patterns of acute respiratory infection hospitalizations before and during two pandemic years

Investigators analyzed the varying pattern of respiratory viruses resulting in hospitalizations from 2012-2013 to 2021-2022 in Canada.

5 Jul 2022

Study looks at pneumococcal carriage among over 60's during COVID pandemic

In a recent article posted to the medRxiv* preprint server, researchers in the United States analyzed the pneumococcal carriage in older adults in the Greater New Haven Area, United States (US), during the implementation of coronavirus disease 2019 (COVID-19) mitigation strategies.

4 Jul 2022

Polymerase News and Research

How can we define early COVID-19 reinfections?

Study reveals sex-based differences in the clinical outcomes of COVID-19 in the US

SARS-CoV-2 spike protein downregulates ACE2 expression

Early detection of SARS-CoV-2 variants via wastewater sequencing uncovers cryptic transmission

Study highlights need to prioritize immunocompromised COVID patients

The putative impact of vitamin D receptor gene polymorphisms on SARS-CoV-2 infection among different variants

Immunogenicity and safety of the protein-based heterodimer booster vaccine for COVID-19

The strength and breadth of antibody responses elicited by hybrid immunity to COVID-19 vaccination or infection alone

Discovery of multiple new SARS-CoV-2 MPro inhibitors

Asymptomatic monkeypox infection detected from routine sexual health samples

Study examines IMPACC trial results to understand clinical phenotypes of disease severity in hospitalized COVID-19 patients

2022 monkeypox presents with new symptoms

The contamination of surfaces in hospital rooms housing monkeypox patients

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

Effectiveness of two and three doses of BNT162b2 against hospital and ED admissions for BA.1 and BA.2 infection

The varying patterns of acute respiratory infection hospitalizations before and during two pandemic years

Study looks at pneumococcal carriage among over 60's during COVID pandemic

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest News