Polymerase News and Research

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Study looks at pneumococcal carriage among over 60's during COVID pandemic

In a recent article posted to the medRxiv* preprint server, researchers in the United States analyzed the pneumococcal carriage in older adults in the Greater New Haven Area, United States (US), during the implementation of coronavirus disease 2019 (COVID-19) mitigation strategies.

4 Jul 2022

Enteric viruses found to transmit through the salivary route

Researchers reported on the productive and persistent infection of salivary glands (SGs) by enteric viruses, with oral cavity titers similar to intestinal titers.

4 Jul 2022

Researchers investigate prevention and therapy against monkeypox infection

Researchers reviewed the preventive and therapeutic measures against monkeypox.

4 Jul 2022

Exploring flavonols in the inhibition of SARS-CoV-2 replication

Researchers assessed the efficiency of flavonols in SARS-CoV-2 inhibition.

4 Jul 2022

Lower diaphragmatic thickness found among long COVID patients with unspecific fatigue and dyspnea

Researchers defined the sonographic diaphragm phenotype of long coronavirus disease (COVID) patients with unspecific fatigue and dyspnea.

4 Jul 2022

Remdesivir resistance in renal transplant patients with long COVID-19

A new study has reported two renal transplant cases, in which individuals, after being exposed to remdesivir, developed a resistance to the drug.

1 Jul 2022

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Researchers assessed the association between obesity and T cell frequencies specific to the SARS-CoV-2 antigen.

1 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

BNT162b2 vaccine induces moderate SARS-CoV-2 immunity in children 5 to 11

In a recent study published in the New England Journal of Medicine, researchers evaluated the effectiveness of the BNT162b2 vaccine against the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron in five to 11-year-old children.

30 Jun 2022

Rapid test can identify which variant has infected a COVID-19 patient in just a few hours

In just a few hours, UT Southwestern scientists can tell which variant has infected a COVID-19 patient – a critical task that can potentially influence treatment decisions but takes days or weeks at most medical centers.

30 Jun 2022

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

Researchers used isothermal amplification with CRISPR-Cas12a to detect SARS-CoV-2.

30 Jun 2022

South African study shows COVID severity of Omicron BA.1, BA.4, BA.5 all similar

A recent article posted to the medRxiv* preprint server analyzed the illness severity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4/BA.5 and prior viral waves in the Western Cape, South Africa.

30 Jun 2022

Research examines possibility of monkeypox transmission in domestic settings

In a recent article posted to the medRxiv* preprint server, researchers conducted environmental sampling for an imported monkeypox virus (MPXV) case in the United Kingdom (UK).

30 Jun 2022

Canada handled COVID well by most measures

In a recent study published in the Canadian Medical Association Journal, researchers assessed how Canada performed on all coronavirus disease 2019 (COVID-19)-related metrics compared to the group of 10 (G10) peer countries: France, Germany, Italy, Belgium, the Netherlands, Sweden, Switzerland, Japan, the United Kingdom, and the United States (US).

30 Jun 2022

SARS-CoV-2 3CLpro also susceptible to mutations

Researchers assess the activity of all potential mutations in the SARS-CoV-2 3CLpro.

29 Jun 2022

Anticancer drug candidate that targets a human protein could be a pan-viral medication

More than two years into the COVID-19 pandemic, people are realizing that the "new normal" will probably involve learning to co-exist with SARS-CoV-2. Some treatments are available, but with new variants emerging, researchers are looking toward new strategies.

29 Jun 2022

The distribution and dynamics of microbial populations on surfaces within a clinical microbiology lab during the COVID-19 pandemic

Researchers evaluated the distribution of microbes on surfaces within a microbiology laboratory.

29 Jun 2022

Polymerase News and Research

Study looks at pneumococcal carriage among over 60's during COVID pandemic

Enteric viruses found to transmit through the salivary route

Researchers investigate prevention and therapy against monkeypox infection

Exploring flavonols in the inhibition of SARS-CoV-2 replication

Lower diaphragmatic thickness found among long COVID patients with unspecific fatigue and dyspnea

Remdesivir resistance in renal transplant patients with long COVID-19

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

BNT162b2 vaccine induces moderate SARS-CoV-2 immunity in children 5 to 11

Rapid test can identify which variant has infected a COVID-19 patient in just a few hours

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

South African study shows COVID severity of Omicron BA.1, BA.4, BA.5 all similar

Research examines possibility of monkeypox transmission in domestic settings

Canada handled COVID well by most measures

SARS-CoV-2 3CLpro also susceptible to mutations

Anticancer drug candidate that targets a human protein could be a pan-viral medication

The distribution and dynamics of microbial populations on surfaces within a clinical microbiology lab during the COVID-19 pandemic

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

3rd COVID vaccine significantly reduced hospitalizations and deaths during Australia's 1st Omicron wave

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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