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Development of multivalent next-generation vaccine strategy against ancestral SARS-CoV-2 and emerging variants

A recent study demonstrated that intranasal (i.n.) delivery of COVID-19 vaccine in murine models elicits greater immune responses against the wildtype SARS-CoV-2 and its variants.

14 Feb 2022

Study explores the gut microbiome of COVID-19 patients

Researchers investigated the changes in the gut microbiome and the presence of SARS-CoV-2 in stool samples of COVID-19 patients.

14 Feb 2022

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

In a study posted to the bioRxiv* preprint server, a team of researchers from the United States evaluated the protective effect of the preclinical version of the current Moderna Omicron-targeted mRNA-1273.529 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 Omicron infection in mice.

14 Feb 2022

Testes found to be a viral reservoir for SARS-CoV-2 replication

In a recent study posted to the medRxiv* pre-print server, researchers used a suite of methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the testis of patients who died from coronavirus disease 2019 (COVID-19) to gain insights into SARS-CoV-2 tropism inside testis and its impact on male fertility.

13 Feb 2022

Wearable sensors for COVID-19 mitigation

In a recent study posted to the medRxiv* pre-print server, researchers simulated several wearable sensor deployment scenarios to demonstrate the potential of digital contact tracing technology in mitigating the coronavirus disease 2019 (COVID-19) pandemic.

13 Feb 2022

Real world evidence on acquired immunity from vaccines and SARS-CoV-2 infection

Researchers assess the incidence of SARS-CoV-2 breakthrough cases and reinfections among unvaccinated and vaccinated individuals.

13 Feb 2022

New COVID-19 test can determine if individuals have been vaccinated, infected, both, or neither

Researchers have created a new T cell assay that allows discrimination of COVID-19 infection and vaccination, as well as the order in which these occurred.

11 Feb 2022

Spillover of SARS-CoV-2 Omicron variant infection in white-tailed deer in New York

Researchers detected evidence for SARS-CoV-2 Omicron variant exposure in the white-tailed deer population inhabiting Staten Island in New York.

10 Feb 2022

Study reports accumulation of SARS-CoV-2 RNA in sewer biofilms

During the COVID-19 pandemic, monitoring the levels of SARS-CoV-2 RNA in wastewater entering treatment plants has been one way that researchers have gauged the disease's spread.

10 Feb 2022

Clinical severity of COVID-19 caused by SARS-CoV-2 variants and the effectiveness of mRNA vaccines against them

A recent study examined the clinical severity of the SARS-CoV-2 Alpha, Delta, and Omicron VOCs and compared vaccine effectiveness against each VOC.

10 Feb 2022

Regular surveillance testing of a community can prevent Covid-19 outbreaks

Covid-19 is often asymptomatic and can lead infected individuals to spread the disease without knowing it. Yet, regular surveillance testing of a community can catch these cases and prevent outbreaks.

10 Feb 2022

New reagent-free SARS-CoV-2 detection technique based on machine learning and Raman spectroscopy

The novel coronavirus, or SARS-CoV-2, which causes the highly contagious COVID-19, has infected millions of people worldwide.

9 Feb 2022

Study explores wastewater surveillance of US military installations to mitigate the spread of SARS-CoV-2

Researchers investigated the application of wastewater surveillance of seagoing military vessels and U.S. coast guard installations to mitigate the spread of SARS-CoV-2.

9 Feb 2022

Simulation of SARS-CoV-2 spread in the United States and India

Researchers used an ABM to simulate SARS-CoV-2 spread in the United States and India.

9 Feb 2022

Impact of SARS-CoV-2 Omicron and Delta variants on serious hospital events

In a new study, a team of researchers assessed the differences in risk of hospitalization in adults after infection with SARS-CoV-2 Omicron and Delta variants.

8 Feb 2022

Exploring the high incidence of croup in children during the SARS-CoV-2 Omicron wave

In a new study, researchers observed that the incidence of pediatric croup was higher during the latest surge of COVID-19 infections driven by the SARS-CoV-2 Omicron variant.

8 Feb 2022

Comparison of school protocols under the high incidence conditions due to the Omicron variant

The current study discusses the proactive vs. reactive school protocols relative to the peak demands for resources, break in infection, and the number of days of school lost.

8 Feb 2022

PCR data sheds light on the dynamics of interspecies pathogen-pathogen interactions

The new study uses PCR data on 17 different pathogens, collected from clinical samples as part of the Seattle Flu Study, a community-based surveillance study of respiratory viral infections.

8 Feb 2022

SARS-CoV-2 in the exhaled breath of COVID-19 patients might be mainly transmitted via respiratory droplets

Researchers found evidence that SARS-CoV-2 particles are released directly into the air through the breathing of COVID-19 patients resulting in respiratory transmission of the virus.

8 Feb 2022

Evidence from a major US metropolitan area on home testing and risk factors for acquisition of SARS-CoV-2 infection

A new study analyzed the risk factors for acquiring COVID-19 in a large, prospective cohort of adult residents in the Boston metropolitan area.

8 Feb 2022

Polymerase News and Research

Development of multivalent next-generation vaccine strategy against ancestral SARS-CoV-2 and emerging variants

Study explores the gut microbiome of COVID-19 patients

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

Testes found to be a viral reservoir for SARS-CoV-2 replication

Wearable sensors for COVID-19 mitigation

Real world evidence on acquired immunity from vaccines and SARS-CoV-2 infection

New COVID-19 test can determine if individuals have been vaccinated, infected, both, or neither

Spillover of SARS-CoV-2 Omicron variant infection in white-tailed deer in New York

Study reports accumulation of SARS-CoV-2 RNA in sewer biofilms

Clinical severity of COVID-19 caused by SARS-CoV-2 variants and the effectiveness of mRNA vaccines against them

Regular surveillance testing of a community can prevent Covid-19 outbreaks

New reagent-free SARS-CoV-2 detection technique based on machine learning and Raman spectroscopy

Study explores wastewater surveillance of US military installations to mitigate the spread of SARS-CoV-2

Simulation of SARS-CoV-2 spread in the United States and India

Impact of SARS-CoV-2 Omicron and Delta variants on serious hospital events

Exploring the high incidence of croup in children during the SARS-CoV-2 Omicron wave

Comparison of school protocols under the high incidence conditions due to the Omicron variant

PCR data sheds light on the dynamics of interspecies pathogen-pathogen interactions

SARS-CoV-2 in the exhaled breath of COVID-19 patients might be mainly transmitted via respiratory droplets

Evidence from a major US metropolitan area on home testing and risk factors for acquisition of SARS-CoV-2 infection

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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