Progestin News and Research

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How does the human gut microbiome impact menopause?

A recent study summarizes available information on the relationship between menopause and the gut microbiome.

24 Aug 2022

Study shows that breast cancer can be prevented with better contraception choices

Hormonal contraceptives, e.g. the pill, the patch, and the vaginal ring, contain synthetic hormones that prevent pregnancy by either stopping ovulation, changing the cervical mucus to stop sperm from passing through the cervix and finding an egg, or changing the womb's lining to prevent a fertilized egg from being implanted in it.

29 May 2021

Contraception counseling, pregnancy planning are necessary to optimize health of women with heart disease

Pregnancy can increase the risk of morbidity and mortality in women with cardiovascular disease; however, many cardiologists are not having pre-pregnancy contraception discussions with their patients of child-bearing age.

5 Apr 2021

Oral contraceptives offer a protective effect against common gynecological cancers

A comprehensive study from Uppsala University, involving more than 250,000 women, shows that oral contraceptive use protects against ovarian and endometrial cancer. The protective effect remains for several decades after discontinuing the use. The study is published in the journal Cancer Research.

17 Dec 2020

Oral hormone therapy significantly alters the metabolome of postmenopausal women

Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women.

16 Dec 2020

Study identifies factors that influence women's decisions regarding therapy options

Removal of the ovaries before natural menopause (surgical menopause) often exacerbates menopause symptoms and places women at increased risk for heart disease, osteoporosis, and cognitive decline.

12 Aug 2020

Woman's genetic make-up may play a role in weight gain from birth control

A woman's genetic make-up may cause her to gain weight when using a popular form of birth control, according to a study from researchers at the University of Colorado Anschutz Medical Campus.

12 May 2020

Elagolix drug suppresses ovarian hormone production, prevents heavy menstrual bleeding

About 50 % of women with uterine fibroids--non-cancerous muscle tumors that grow in the uterus--experience heavy menstrual bleeding and other symptoms. Surgery is commonly recommended when these symptoms are severe enough to prompt a woman to seek treatment.

23 Jan 2020

Society for Maternal-Fetal Medicine releases statement in response to PROLONG trial results

The Society for Maternal-Fetal released the following statement in response to the published results of "Progestin's Role in Optimizing Neonatal Gestation," more commonly referred to as the PROLONG trial, which was recently published in the American Journal of Perinatology.

25 Oct 2019

Hormone therapy decreases metabolites directly linked with Type 2 diabetes

The Women's Health Initiative remains one of the most highly quoted when debating the benefits and risks of hormone therapy.

24 Sep 2019

Male contraceptive pill crosses the human clinical trial hurdle

Birth control pills have been around for the past six decades but have been for use of women only. A team of researchers this week have announced the success of the first male birth control pill that could safely prevent pregnancy.

27 Mar 2019

Gel formulation of a new male contraceptive on trial

The National Institutes of Health (NIH) is funding a clinical trial to see the safety and effectiveness of a new male contraceptive that would be available in gel formulation.

29 Nov 2018

TherapeuticsMD announces FDA approval of BIJUVA capsules to manage vasomotor symptoms of menopause

TherapeuticsMD, Inc., an innovative women's healthcare company, today announced that the United States Food and Drug Administration has approved BIJUVA (estradiol and progesterone) capsules, 1 mg/100 mg, the first and only FDA-approved bio-identical hormone therapy combination of estradiol and progesterone in a single, oral capsule for the treatment of moderate to severe vasomotor symptoms (commonly known as hot flashes or flushes) due to menopause in women with a uterus.

29 Oct 2018

Woman's PR-status may help develop personalized approach to treating endometriosis

Endometriosis -- a condition caused by uterine tissue growing outside of the organ -- affects 10% of reproductive-aged women, whom it causes chronic pain that is significant and debilitating.

25 Oct 2018

Biomarkers can predict treatment response in women with endometriosis

Biomarkers can predict whether women will respond to the first-line treatment for endometriosis, an extremely painful condition in which the tissue usually found inside the uterus grows in places it shouldn't, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

24 Oct 2018

Ovarian cancer risk reduced among women taking modern combined oral contraceptive pills

According to a new study women of reproductive age who are using the modern oral contraceptive pills or patches and rings that contain a combination of estrogen and progesterone are at a reduced risk for ovarian cancer. The study was published in the recent issue of the British Medical Journal (BMJ).

27 Sep 2018

FDA approves first vaginal ring contraceptive that can be used for one year

The U.S. Food and Drug Administration today approved Annovera (segesterone acetate and ethinyl estradiol vaginal system), which is a combined hormonal contraceptive for women of reproductive age used to prevent pregnancy and is the first vaginal ring contraceptive that can be used for an entire year.

10 Aug 2018

Combe announces launch of Preventeza Emergency Contraceptive and campaign

Combe Inc., the makers of Vagisil, today announced the launch of its Preventeza Emergency Contraceptive #WeAre1in2 campaign to showcase solidarity around women's reproductive rights.

6 Jul 2018

Male birth control pill taken once a day shows success

A new birth control pill for men with a hormonal component has shown efficacy and safety in preventing pregnancies when used once daily for a month. The study was presented yesterday (18th of March 2018) at the ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, Illinois.

19 Mar 2018

Oral contraceptives increase ischemic stroke risk

Oral contraceptives increase the risk of ischemic stroke, but this risk is very small among women who do not have other stroke risk factors, according to a comprehensive review in the journal MedLink Neurology by Loyola Medicine stroke specialists.

5 Mar 2018