Progestin News and Research

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Study provides reassurance regarding the safety of using hormone therapy after age 65 years

After the Women's Health Initiative (WHI) in 2002, many women have resisted taking hormone therapy (HT), especially after age 65 years, because of fears of increased risks for various cancers and heart disease.

10 Apr 2024

New review aims to help clinicians diagnose and manage PCOS

A recent review article in CMAJ explores the state of current knowledge on the diagnosis and treatment of this chronic disorder.

30 Jan 2024

Does space travel impact the human reproductive system?

How space travel, space radiation, and microgravity affect human reproductive functions.

22 Jan 2024

How do sex hormones and birth control affect brain fear circuits?

Researchers explores how oral contraceptive pill use interacts with the current hormonal status to affect the fear circuit structure within the brain.

9 Nov 2023

Clotting risk from birth control normalizes within weeks of stopping hormonal contraceptives

Using birth control pills and other hormone-based contraceptives is known to elevate the risk of blood clots about three-fold, but a new study suggests that this risk largely goes away within two to four weeks after one stops using these contraceptives, according to research published today in Blood.

8 Nov 2023

Managing menopause: The 2023 toolkit for healthcare practitioners

The authors of the revised 2023 Toolkit extracted key recommendations from professional guidelines and positions as well as consensus statements on menopause and related conditions that have emerged since 2014.

1 Nov 2023

New research sheds light on metabolic problems faced by transgender people

The latest data on the metabolic problems faced by trans people are presented at a session at this year's Annual Meeting of the European Association for the Study of Diabetes (Hamburg 2-6 October).

6 Oct 2023

How does taking a pause on the oral contraceptive pill impact mental health?

Users of combination oral contraceptive agents experience one time per month (pill break) was connected with mood changes.

28 Sep 2023

NSAID use linked to higher risk of blood clots in women of reproductive age, association stronger in women on high-risk hormonal contraception

A new paper published in The BMJ explores the effect of these drugs used concomitantly on the risk of venous thromboembolism (VTE).

8 Sep 2023

Women using NSAIDs alongside hormonal contraception may be at increased risk of blood clots

Women who use non-steroidal anti-inflammatory painkillers alongside hormonal contraception appear to be at a small increased risk of blood clots known as venous thromboembolism (VTE), finds a large Danish study published by The BMJ today.

7 Sep 2023

Once the new over-the-counter birth control pill is available, What about cost and coverage?

Last week, the FDA approved Opill, the first daily oral contraceptive that will be available for sale over the counter in stores as well as online. Reproductive health advocates hailed the groundbreaking approval as a step that can help millions of people avoid pregnancy, which is unintended nearly half the time in the United States.

19 Jul 2023

Study links menopausal hormone therapy to increased risk of dementia and Alzheimer's

Research investigates the impact of menopausal hormone therapy on the risk of developing dementia, considering different types of hormone treatment, duration of use, and age at usage. The study aims to assess the association between hormone therapy and dementia development.

3 Jul 2023

Menopausal hormone therapy associated with increased rate of dementia and Alzheimer's disease

Use of menopausal hormone therapy is associated with an increased rate of dementia and Alzheimer's disease, suggests a large Danish study published by The BMJ today.

3 Jul 2023

Use of menopausal hormone therapy associated with increased rate of dementia and Alzheimer's

Use of menopausal hormone therapy is associated with an increased rate of dementia and Alzheimer's disease, suggests a large Danish study published by The BMJ today.

28 Jun 2023

Women taking oral estrogen therapy more likely to develop high blood pressure

Women ages 45 years and older taking estrogen hormone therapy in pill form were more likely to develop high blood pressure than those using transdermal (topical, applied to the skin) or vaginal formulations, according to new research published today in Hypertension, a peer-reviewed American Heart Association journal.

5 Jun 2023

Examining the effect of hormone replacement therapy on postmenopausal heart disease and cognitive decline

Many are aware of the short-term symptoms often associated with menopause, such as hot flashes, which are attributed to changes in reproductive hormones.

9 Mar 2023

Patient mistrust and poor access hamper federal efforts to overhaul family planning

Two years ago, after an emergency cesarean section at a Mississippi hospital, Sherika Trader was denied a tubal ligation. Trader, now 33, was told that to have her tubes tied, she had to have a second child or a husband's permission, even though she wasn't married.

21 Nov 2022

More babies, lower risk of endometrial cancer

While many highly industrialized and developed countries report falling or negative population growth rates due to a rapid decrease in the number of babies born each year, a new report adds more strength to the evidence that bearing a baby has a protective effect on the endometrium, the lining of the womb, reducing the risk of endometrial cancer.

8 Nov 2022

Combined oral contraceptive pills do not appear to exacerbate macromastia-related symptoms

Combined oral contraceptives (COCs) containing both estrogen and progestin do not contribute to the development of enlarged breasts (macromastia) – nor do they increase the risk of breast regrowth in adolescents and young women following breast-reduction surgery, reports a study in the October issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

29 Sep 2022

Combined oral contraceptives associated with elevated risk of venous thromboembolism in obese women

Obese women who use oral contraceptives containing estrogen and progestin have a 24-fold increased risk of venous thromboembolism (VTE) compared with non-obese women not using the drugs, according to a review paper published today in ESC Heart Failure, a journal of the European Society of Cardiology (ESC).

14 Sep 2022