Proliferation News and Research

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Protein points to anticancer drug targets

A unique tail at one end of a protein called Ubc12 stabilizes a molecular workshop that assembles the “on-switch cells” used to accelerate cell replication.

20 Sep 2004

Mitomycin C offers limited benefit in reducing unsightly scars

The tendency for extreme scarring is one reason many African Americans avoid plastic surgery and other surgical incisions. Though surgeons continue to develop less invasive techniques that minimize scarring, other options are needed to help these individuals who are prone to developing keloid scars.

17 Sep 2004

Liver cancer genes cluster into two subsets that correlate to survival

An analysis of the gene expression patterns of 91 unrelated liver tumors revealed two distinctive subclasses highly associated with patient survival, according to a new study published in the September 2004 issue of Hepatology.

14 Sep 2004

New treatment for T-cell acute lymphoblastic leukaemia

IL-7, a hormone-like protein involved in cell-cell interaction, has been associated with increased survival and expansion of T-cell acute lymphoblastic leukaemia (T-ALL).

9 Sep 2004

Major trends in AIDS research that the different research teams throughout the world are pursuing

The science will be presented during the conference which is taking place in Lausanne until September 1, 2004. The advances in fundamental research, notably through a better understanding of the complex processes of immune defence, HIV and the functioning of vaccines, promote the genesis and development of new vaccine candidates.

30 Aug 2004

Gene - beta1-integrin, could be key to breast cancer therapies

Canadian researchers at the Research Institute of the McGill University Health Centre and McMaster University have identified a new player in breast cancer. This gene, beta1-integrin, has been shown to be critical in the initiation of tumour growth and development in a mouse model of cancer.

30 Aug 2004

Scientists have discovered a protein that could be the key to finding a cure for asthma

Scientists at the University's Department of Pharmacology and the Woolcock Institute of Medical Research have discovered a protein produced in human lung cells that could be the key to finding a cure for asthma.

25 Aug 2004

Future for telemedicine is a very bright one

The European telemedicine markets are at a critical growth phase where vendors need to capitalise on growing opportunities and gain the early-mover advantage over competitors.

23 Aug 2004

Consumer education campaign warning Connecticut residents of the dangers of illegal drug importation

Connecticut became the sixteenth state to join forces with the FDA to launch the "Looks Can Be Deceiving" educational campaign. During a press conference in Hartford, officials from CPA unveiled examples of the more than 40,000 flyers and prescription bag inserts that have been sent to 166 pharmacies across Connecticut.

18 Aug 2004

Drug-eluting stents (DES), increasingly used in coronary angioplasty, have benefits over bare-metal stents

A pooled analysis of 11 previously published trials provides evidence that drug-eluting stents (DES)—increasingly used in coronary angioplasty—have benefits over bare-metal stents (BMS) by reducing the need for later revascularisation and reducing the risk of cardiac events

15 Aug 2004

Receptor for estrogen in ovarian cells has been shown to suppress tumor growth

An important receptor for estrogen in ovarian cells has been shown to suppress tumor growth, according to a new study published in the August 15 issue of the journal Cancer Research.

15 Aug 2004

WHO tackles the parasitic disease Leishmaniasis in Afghanistan

A rapid intervention by the World Health Organization and its partners, the Massoud Foundation and HealthNet International, in Kabul, Afghanistan, made possible by a donation from the Belgian government, should dramatically reduce the incidence of leishmaniasis in less than two years.

10 Aug 2004

Discovery could revolutionise the way asthma is treated and managed, and possibly lead to an eventual cure

A major discovery by scientists at the Woolcock Institute of Medical Research could revolutionise the way asthma is treated and managed, and possibly lead to an eventual cure.

9 Aug 2004

Protein loss plays role in acute T-cell leukemia

The loss of a key protein (Smad3) in a pathway that helps prevent tumors from forming is specific to one form of childhood leukemia, but not to other pediatric and adult forms of leukemia, according to a new study published in the August 5, 2004, New England Journal of Medicine.

5 Aug 2004

One-third of U.S. adults use some form of alternative medicine

More than one-third of U.S. adults use some form of alternative medicine such as herbal supplements and other therapies, showed in a nationwide survey by NIH's National Center for Complementary and Alternative Medicine published in May 2004.

2 Aug 2004

Hormone that is important in the control of blood pressure may also inhibit the growth of lung cancer cells

Their studies found that angiotensin-(1-7) significantly slows the growth of three different types of human lung cancer cells in the laboratory. "Our experiments provide the first evidence that angiotensin-(1-7) inhibits the proliferation of human lung cancer cells," they said.

2 Aug 2004

Prohibition of the sale of water-laced with nicotine to minors under the age of 18

Governor George E. Pataki has signed legislation into law that prohibits the sale of water-laced with nicotine to minors under the age of 18.

26 Jul 2004

Y's Therapeutics files for clinical trials in Europe for rheumatoid arthritis and asthma

Y's Therapeutics, a privately held biopharmaceutical company, said today it has submitted applications to the Ethics Committee and Ministry of Health (BfArM) in Germany to begin Phase II clinical trials for its two most advanced projects, YSIL6 for rheumatoid arthritis and YSTH2 for asthma.

26 Jul 2004

New compound that is designed to overcome Gleevec resistance

One of the truly spectacular success stories in modern oncology is the development and implementation of Gleevec, a drug that virtually halts the progress of chronic myeloid leukemia. Yet for some patients who harbor particularly stubborn genetic mutations, Gleevec fails miserably.

17 Jul 2004

A drug derived from an ocean-growing sponge helps prevent the growth of cancer cells

A drug derived from an ocean-growing sponge teams up to enhance the performance of the yew tree derivative Taxol® (paclitaxel) in preventing the growth of cancer cells, according to research published in the July 15 issue of the journal Cancer Research.

15 Jul 2004