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Discovery of a novel therapeutic target for pancreatic cancer

A novel amino acid transporter-based therapeutic target for pancreatic ductal adenocarcinoma (PDAC).

10 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

Study sheds light on PRMT1's role in gastric cancer progression

In a study published in the journal Genes & Diseases, researchers from Southwest University, and Southwest Medical University investigated PRMT1, a protein previously known to be overexpressed in gastric cancer cells.

9 Oct 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Spanish researchers use cisgenic engineering to create nutrient-packed tomatoes with higher levels of flavonoids and branched-chain amino acids, providing potential benefits for those on plant-based diets. The study shows promise for enhancing nutritional content in other crops, addressing malnutrition and health deficiencies.

27 Sep 2023

Research provides key insights into the molecular underpinnings of acute liver injury

In a study published in the journal of Genes & Diseases, a team of researchers from Chonnam National University and the Korea Research Institute of Bioscience and Biotechnology unveiled important insights into liver injury and its underlying molecular mechanisms.

14 Sep 2023

Rasip1 gene found to be intimately involved in the creation of blood cells

Blood has long been a symbol of life and health, so it may be surprising that some aspects of blood production, i.e., hematopoiesis, remain incompletely understood.

13 Sep 2023

Study sheds new light on the role of 'TonEBP' protein in lupus and lupus nephritis

A groundbreaking discovery has been made by Professor Hyug Moo Kwon and his research team in the Department of Biological Sciences at UNIST, in collaboration with Professor Jaeseok Yang from Yonsei University.

13 Sep 2023

Arf1 inhibition induces tumor regression by promoting T cell infiltration

In recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have been highly successful and have become an important basis for the future treatment of cancers.

12 Sep 2023

Dietary cholesterol and fruit tannins synergistically promote kidney stone formation

Kidney stones (KS), hard crystalline formations that occur within the kidney, are a common condition that affects millions of people worldwide.

11 Sep 2023

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Researchers across Europe have delved into the DNA methylation patterns in CD4+ T-cells of psoriasis and psoriatic arthritis (PsA) patients, unveiling potential new biomarkers for these conditions. Their study suggests that these unique profiles could serve as both diagnostic and prognostic tools, although further validation is needed for real-world clinical application.

10 Sep 2023

Promising new cervical cancer test fills in the gap missed by Pap tests

Researchers assessed a novel human papillomavirus (HPV) and host deoxyribonucleic acid (DNA) methylation score for adenocarcinoma in-situ (AIS) and cervical adenocarcinoma (ADC) screening.

8 Sep 2023

Lessons learned from COVID-19 pandemic can help confront future epidemics

Where did COVID-19 originate? Prof Angus Dalgleish shows that the virus that emerged in Wuhan, China in 2019 had been modified in a laboratory to make it more infectious (for the construction of a more effective vaccine).

1 Sep 2023

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

An online resource for studying the relationship between mutational signatures and topographical characteristics across human cancer.

28 Aug 2023

The interplay between the microbiota, the epigenome, and nutrition among obese adults during behavioral weight reduction

Study evaluated associations between gut microbiome (MB), deoxyribonucleic acid (DNA) methylation (DNAme), and nutrition.

21 Aug 2023

Early lung cancer detection with a machine learning model based on imaging, clinical, and DNA methylation biomarkers

Researchers discuss the development and validation of a combined model for the early diagnosis of lung cancer.

15 Aug 2023

Epigenetic manipulation may improve breast cancer treatment responses

Researchers explore the possibility of increasing TROP2 ADC activity by enhancing the expression of TROP2 on cancer cells.

15 Aug 2023

Epigenetic drug-sensitive biomarkers for cancer

Researchers perform an epigenome-wide multi-omic high-throughput screen to identify actionable epigenetic drug-sensitive biomarkers.

15 Aug 2023

Study reveals the health and dietary benefits of consuming cardamom

A new study by Texas A&M AgriLife revealed a range of health and dietary benefits of consuming cardamom, including increased appetite, fat loss and inflammation reduction, making the spice a "superfood."

13 Aug 2023

Study reveals APOE-ε4 allele increases the risk for Alzheimer's and cardiovascular disease

Previous research has revealed that the Apolipoprotein-ε4 (APOE-ε4) allele increases the risk for a variety of diseases in aging populations, specifically Alzheimer's and cardiovascular disease. And yet, despite the negative effects of this genetic variant, it remains prevalent in approximately 20% of the human population.

11 Aug 2023

Promoter News and Research

Discovery of a novel therapeutic target for pancreatic cancer

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

Study sheds light on PRMT1's role in gastric cancer progression

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Supercharged tomatoes: Scientists engineer fruits packed with amino acids and flavonoids

Research provides key insights into the molecular underpinnings of acute liver injury

Rasip1 gene found to be intimately involved in the creation of blood cells

Study sheds new light on the role of 'TonEBP' protein in lupus and lupus nephritis

Arf1 inhibition induces tumor regression by promoting T cell infiltration

Dietary cholesterol and fruit tannins synergistically promote kidney stone formation

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Promising new cervical cancer test fills in the gap missed by Pap tests

Lessons learned from COVID-19 pandemic can help confront future epidemics

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

The interplay between the microbiota, the epigenome, and nutrition among obese adults during behavioral weight reduction

Early lung cancer detection with a machine learning model based on imaging, clinical, and DNA methylation biomarkers

Epigenetic manipulation may improve breast cancer treatment responses

Epigenetic drug-sensitive biomarkers for cancer

Study reveals the health and dietary benefits of consuming cardamom

Study reveals APOE-ε4 allele increases the risk for Alzheimer's and cardiovascular disease

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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