Prophylaxis News and Research

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Mpox persists in England: Strong vaccine effectiveness, stay vigilant

Study found that mpox cases in England remained low but steady in 2023, with the MVA-BN vaccine showing 82% effectiveness in preventing severe disease, particularly among GBMSM.

29 Aug 2024

Study finds minimal impact of cesarean antibiotics on infant gut microbiome

Cesarean section recipients are usually given prophylactic antibiotics just before the procedure to prevent later infections at the surgical site.

14 Aug 2024

UMass Amherst and Tufts Medical Center launch study to improve HIV care for incarcerated individuals

The University of Massachusetts Amherst and Tufts Medical Center are conducting a study to provide HIV prevention, diagnosis and treatment for people with opioid use disorders who are incarcerated in the Boston area.

9 Aug 2024

Rare but real: The neurological risks associated with vaccines

Review highlights the rare neurological risks associated with vaccination, emphasizing the importance of accurate detection and management strategies, particularly in the context of the COVID-19 pandemic.

9 Aug 2024

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

Emory researcher David Weiss has spent years studying a baffling phenomenon called heteroresistance, in which a tiny fraction of bacteria remain resistant to antibiotics, while the remainder succumb.

2 Aug 2024

Reliability of HIV viral load tests for CAB-LA PrEP questioned in new study

A single laboratory-based HIV viral load test used by U.S. clinicians who provide people with long-acting, injectable cabotegravir (CAB-LA) HIV pre-exposure prophylaxis (PrEP) did not reliably detect HIV in a multi-country study.

23 Jul 2024

Long-acting injectable CAB-LA safe for HIV PrEP during pregnancy, study finds

Long-acting injectable cabotegravir (CAB-LA) was safe and well tolerated as HIV pre-exposure prophylaxis (PrEP) before and during pregnancy in the follow-up phase of a global study among cisgender women.

23 Jul 2024

PrEPVacc HIV vaccine trial shows no reduction in infections

The results of the PrEPVacc HIV vaccine trial conducted in Eastern and Southern Africa, which ran between 2020 and 2024, show conclusively that neither of the two experimental vaccine regimens tested reduced HIV infections among the study population.

23 Jul 2024

Pentamidine: A promising prophylactic against chlamydial infections

Despite the significant increase in sexually transmitted diseases in recent years, there is currently no vaccine available against common bacterial pathogens such as chlamydia.

9 Jul 2024

Lenacapavir: A breakthrough in long-acting HIV prevention for cisgender women

The injectable antiretroviral drug lenacapavir was safe and 100% effective as long-acting HIV pre-exposure prophylaxis (PrEP) among cisgender women in a Phase 3 clinical trial, according to top-line findings released by Gilead Sciences, Inc., the study sponsor.

26 Jun 2024

Young gay Latinos see rising share of new HIV cases, leading to call for targeted funding

Four months after seeking asylum in the U.S., Fernando Hermida began coughing and feeling tired. He thought it was a cold.

24 Jun 2024

Breakthrough in hemophilia A treatment: Sobi's ALTUVOCT receives EU marketing authorization

Sobi® today announced the European Commission has granted Marketing Authorization for ALTUVOCT™ (efanesoctocog alfa), for the treatment and prevention of bleeds and perioperative prophylaxis in hemophilia A. ALTUVOCT is a high-sustained factor VIII replacement therapy for all ages and any disease severity.

22 Jun 2024

Paternal and maternal transplants boost infant gut health after cesarean delivery

Researchers explore the paternal role in infant gut seeding and the impact of induced seeding by maternal fecal microbiota transplant.

16 Jun 2024

Global study confirms pantoprazole's role in reducing upper GI bleeding in the ICU

A widely available drug helps prevent upper gastrointestinal bleeding in critically ill adults on a breathing machine, according to the results of a global study and meta-analysis led by researchers at McMaster University.

14 Jun 2024

Gavi announces funding for human rabies vaccines in global effort to eliminate disease

Gavi, the Vaccine Alliance, in collaboration with partners, is announcing support for human rabies vaccines for post-exposure prophylaxis (PEP) as part of routine immunization.

13 Jun 2024

Berotralstat: A promising oral treatment for hereditary angioedema with normal C1-inhibitor

BioCryst Pharmaceuticals, Inc. today announced new real-world evidence showing that patients with hereditary angioedema (HAE) who have normal C1-inhibitor (HAE-nC1-INH) level and function had a reduction in monthly attack rates after starting oral, once-daily berotralstat.

8 Jun 2024

Doxycycline shows promise in reducing deaths and seizures from nodding syndrome

A new study suggests that a course of the drug doxycycline can decrease acute seizure-related hospitalization and deaths related to nodding syndrome.

8 Jun 2024

Complexities and emotional challenges of STI disclosure to sexual partners

A review of research to-date reveals the complex nature of revealing a diagnosis of a sexually transmitted infection (STI) to a partner ahead of engaging in sexual activity.

6 Jun 2024

$Preoperative antibiotic treatment does not reduce infection risk after pediatric elbow fracture surgery$

Preoperative antibiotic treatment does not reduce infection risk after pediatric elbow fracture surgery

Antibiotic treatment prior to surgical repair of a pediatric elbow fracture does not reduce the risk for post-operative infection, according to new findings from a team of researchers and surgeons from the University of Missouri School of Medicine.

5 Jun 2024

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

A new treatment approach using an older drug may enable more patients with high-risk blood cancers to receive transplanted stem cells from unrelated, partially matched donors, according to a study conducted by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and colleagues.

23 May 2024

Prophylaxis News and Research

Mpox persists in England: Strong vaccine effectiveness, stay vigilant

Study finds minimal impact of cesarean antibiotics on infant gut microbiome

UMass Amherst and Tufts Medical Center launch study to improve HIV care for incarcerated individuals

Rare but real: The neurological risks associated with vaccines

Study links fungal heteroresistance to fatal bloodstream infections in bone marrow transplant patients

Reliability of HIV viral load tests for CAB-LA PrEP questioned in new study

Long-acting injectable CAB-LA safe for HIV PrEP during pregnancy, study finds

PrEPVacc HIV vaccine trial shows no reduction in infections

Pentamidine: A promising prophylactic against chlamydial infections

Lenacapavir: A breakthrough in long-acting HIV prevention for cisgender women

Young gay Latinos see rising share of new HIV cases, leading to call for targeted funding

Breakthrough in hemophilia A treatment: Sobi's ALTUVOCT receives EU marketing authorization

Paternal and maternal transplants boost infant gut health after cesarean delivery

Global study confirms pantoprazole's role in reducing upper GI bleeding in the ICU

Gavi announces funding for human rabies vaccines in global effort to eliminate disease

Berotralstat: A promising oral treatment for hereditary angioedema with normal C1-inhibitor

Doxycycline shows promise in reducing deaths and seizures from nodding syndrome

Complexities and emotional challenges of STI disclosure to sexual partners

Preoperative antibiotic treatment does not reduce infection risk after pediatric elbow fracture surgery

New stem cell transplant approach may expand donor pool for high-risk blood cancer patients

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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