Prophylaxis News and Research

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Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

Understanding measles and the role of vaccination

With measles cases rising in Canada and internationally, it is important for clinicians to understand the disease and the role of vaccination against measles.

22 Apr 2024

Breast milk's secret weapon against RSV revealed in new study

Researchers explored how human milk oligosaccharides (HMOs) protect infants from respiratory syncytial virus (RSV), suggesting that these components in breast milk may prevent or reduce the severity of RSV infections through multiple mechanisms including gut microbiome modulation and direct antiviral actions.

15 Apr 2024

ChatGPT could be an effective tool to help reduce vaccine hesitancy

New research being presented at this year's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) suggests that the free-to-use, widely accessible ChatGPT could be an effective tool to help reduce vaccine hesitancy among the general public, as well as providing helpful advice on sexually transmitted infections (STIs) in conjunction with sexual health clinics, by improving knowledge and access to care.

10 Apr 2024

New report on HIV drug resistance: Challenges and recommendations

The World Health Organization's (WHO) latest HIV Drug Resistance (HIVDR) Report tells us where drug resistance is growing and offers recommendations for countries to monitor and respond to the potential challenges.

1 Apr 2024

Case study: Monkeypox breakthrough infection in fully vaccinated individual

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases in Barcelona, Spain (27-30 April) details the case of a man who had received two doses of the monkey pox vaccine in Autumn, 2022 yet experienced a 'breakthrough' mpox infection in January 2024.

1 Apr 2024

Rethinking PrEP's role in prevention of sexually transmitted infections

In their research article published in Eurosurveillance, von Schreeb et al. challenge existing assumptions regarding the relationship between the use of HIV pre-exposure prophylaxis (PrEP) and the incidence of bacterial sexually transmitted infections (STI).

28 Mar 2024

Rising antimicrobial resistance in STIs: A call for global action

Review delves into the rising challenge of antimicrobial resistance in sexually transmitted infections, underscoring the need for innovative treatments and the critical role of global surveillance in managing diseases like gonorrhea and syphilis.

21 Mar 2024

Watch: Many Americans are unaware of HIV prevention medication

Céline Gounder, KFF Health News' editor-at-large for public health, explained on "CBS Mornings" why many at-risk Americans do not know about medication to prevent HIV infection through sexual contact or do not have access to it.

20 Mar 2024

Measles outbreak in Illinois underscores critical need for vaccination

Study reports a measles outbreak among five unvaccinated children in Illinois, highlighting the disease's high transmissibility even among those not in direct contact, underscoring the critical importance of vaccination.

17 Mar 2024

UArizona study identifies link between poor sleep and migraine attacks

A new study by researchers at the University of Arizona Health Sciences identified a link between poor sleep and migraine attacks that suggests improving sleep health may diminish migraine attacks in people with migraine.

13 Mar 2024

Vaginal ring and oral PrEP found to be safe for HIV prevention among pregnant cisgender women

The monthly dapivirine vaginal ring and daily oral pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate and emtricitabine were each found to be safe for HIV prevention among cisgender women who started using one of them in their second trimester of pregnancy, according to findings presented today at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI) in Denver.

5 Mar 2024

Combination interventions increase PrEP uptake among at-risk youth, study shows

A UCLA Health-led study found a combination of interventions of one-on-one telehealth coaching, peer support forums, and automated text messages more than doubled the use of the HIV prevention strategy, called PrEP, among younger, at-risk Americans, a group that historically has had low use of the medication.

22 Feb 2024

Missing gut microbes after antibiotics and a high-fat diet may be to blame for sugar-free candy and gum giving you gas

A recent Cell study showed how a high-fat diet and antibiotic exposure could trigger sorbitol intolerance by depleting Clostridia from the gut microbiota.

20 Feb 2024

Drug repurposing study finds lonafarnib effective against RSV

A study in Nature Communications identifies lonafarnib from the ReFRAME drug-repurposing library as a potent inhibitor of the RSV fusion protein, showing promise in reducing RSV infection in vitro and in vivo.

11 Feb 2024

Impact of nirsevimab immunization on pediatric RSV-related hospitalizations in Luxembourg

Respiratory syncytial virus (RSV) is one of the main reasons leading to hospitalization among young children worldwide and each year, an estimated 101,000 children below the age of 5 years die due to RSV infections.

30 Jan 2024

Research projects aim to develop breakthrough digital technology for improving heart and brain health

A special issue of the Journal of the American Heart Association spotlights the progress of ongoing projects aimed at developing breakthrough digital technology solutions to improve heart and brain health on a global scale.

16 Jan 2024

Study shows engineered antibodies significantly boost Omicron neutralization

Researchers engineered IgA antibodies from IgG monoclonals, enhancing neutralization against Omicron by up to 75-fold and offering protection in mice models.

10 Jan 2024

Combined vaccination and behavior change efforts averted 64% of US mpox cases, study reveals

The effectiveness of the combination of current preventive responses against monkeypox (Mpox).

10 Jan 2024

New study sheds light on the biological properties of new COVID variant Pirola

Despite the end of the pandemic, COVID-19 continues to pose a serious health threat. Most individuals have established robust immune protection and do not develop severe disease but the infection can still lead to marked and sometimes long-lasting disease symptoms.

9 Jan 2024