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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Maternal inflammation in maternal blood linked with greater risk for schizophrenia in offspring

Maternal inflammation as indicated by the presence in maternal blood of early gestational C-reactive protein-an established inflammatory biomarker-appears to be associated with greater risk for schizophrenia in offspring, according to researchers at Columbia University's Mailman School of Public Health, Columbia University Medical Center, and the New York State Psychiatric Institute.

8 Jul 2014

Scientists discover new compounds that could alter circadian rhythm

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered a surprising new role for a pair of compounds—which have the potential to alter circadian rhythm, the complex physiological process that responds to a 24-hour cycle of light and dark and is present in most living things.

8 Jul 2014

Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

Lysosomes are subcellular organelles that are present in most cells, with the major exception of red blood cells.

8 Jul 2014

Pseudogenes may play key role in the discovery of new biomarkers

Dysfunctional, unloved and seemingly of little use, these poor-cousin relatives of genes have lost their protein-coding abilities. They contain material not essential for an organism's survival and are the "last stop" for removal of genomic waste.

8 Jul 2014

Study provides new knowledge about EphA2 receptor involved in several forms of cancer

Researchers at Karolinska Institutet in Sweden have headed a study that provides new knowledge about the EphA2 receptor, which is significant in several forms of cancer. This is important knowledge in itself - but just as important is how this study, which is published in the highly respected journal Nature Methods, was conducted.

8 Jul 2014

Lack of leisure-time physical activity linked to increased obesity, particularly in young women

Sedentary lifestyle and not caloric intake may be to blame for increased obesity in the US, according to a new analysis of data from the National Health and Nutrition Examination Survey (NHANES).

8 Jul 2014

Penn’s immunotherapy receives FDA's Breakthrough Therapy designation for ALL treatment

A University of Pennsylvania-developed personalized immunotherapy has been awarded the U.S. Food and Drug Administration's Breakthrough Therapy designation for the treatment of relapsed and refractory adult and pediatric acute lymphoblastic leukemia (ALL).

7 Jul 2014

Treating ulcerative colitis and Crohn’s disease

Ulcerative colitis and Crohn’s disease are idiopathic (we don’t know the cause) inflammatory diseases (IBD) of the colon and/or small bowel. They are chronic in that we do not have a medical cure and are differentiated from IBS (irritable bowel syndrome) by inflammation that causes ulcerations of the GI tract.

7 Jul 2014

Researchers find novel inhibitor that prevents cholera toxin from binding to carbohydrates

Cholera against cholera: a novel inhibitor prevents the cholera toxin from binding to carbohydrates found on the surface of intestinal cells.

7 Jul 2014

Standard risk factors stratify already high-risk diabetic patients

Cardiovascular disease risk factors are associated with mortality even among patients with Type 2 diabetes who are already at high risk due to having high coronary artery calcified plaque, say researchers.

4 Jul 2014

High level of adiponectin linked to decreased risk of diabetes, cardiovascular disease

It has been known for its flavorful addition to soups and as a delicacy for dogs but bone marrow fat may also have untapped health benefits, new research finds.

4 Jul 2014

CNIOA researchers update number of human genes to 19,000

How nutrients are metabolised and how neurons communicate in the brain are just some of the messages coded by the 3 billion letters that make up the human genome.

4 Jul 2014

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a chemical "switch" that controls both the generation of new neurons from neural stem cells and the survival of existing nerve cells in the brain.

4 Jul 2014

Transcription factor IRF4 plays key role in brown fat's thermogenic process

The body contains two types of fat cells, easily distinguished by color: White and brown. While white fat serves to store excess calories until they're needed by the body, brown adipocytes actually burn fat by turning it into heat.

4 Jul 2014

Plasmonic biosensors: A key asset in personalised medicine

A new type of high-sensitivity and low-cost sensors, called plasmonic biosensors, could ultimately become a key asset in personalised medicine by helping to diagnose diseases at an early stage.

4 Jul 2014

Research: New protein complex fights against bacterial infection that causes gastric cancer

New study by Cancer Science Institute of Singapore at NUS show that the protein is produced as an immune response and requires the tumour suppressor RUNX3.

4 Jul 2014

Researchers identify pathogenic mechanism common to several neurodegenerative diseases

An international team of researchers identified a pathogenic mechanism that is common to several neurodegenerative diseases. The findings suggest that it may be possible to slow the progression of dementia even after the onset of symptoms.

4 Jul 2014

Researchers reveal how schizophrenia-linked genetic variation alters skeletons of developing brain cells

Johns Hopkins researchers have begun to connect the dots between a schizophrenia-linked genetic variation and its effect on the developing brain. As they report July 3 in the journal Cell Stem Cell, their experiments show that the loss of a particular gene alters the skeletons of developing brain cells, which in turn disrupts the orderly layers those cells would normally form.

4 Jul 2014

Researchers unlock secret behind the activation of Ras proteins

A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy.

4 Jul 2014

Leading hypothesis for miscarriages, birth defects ruled out by WSU reproductive biologists

Washington State University reproductive biologists have ruled out one of the leading thoughts on why older women have an increased risk of miscarriages and children with birth defects.

4 Jul 2014

Protein News and Research

Further Reading

Maternal inflammation in maternal blood linked with greater risk for schizophrenia in offspring

Scientists discover new compounds that could alter circadian rhythm

Fabry disease awareness: an interview with Dr. Hartmann Wellhoefer, Head of Medical Affairs, Rare Disease, Shire

Pseudogenes may play key role in the discovery of new biomarkers

Study provides new knowledge about EphA2 receptor involved in several forms of cancer

Lack of leisure-time physical activity linked to increased obesity, particularly in young women

Penn’s immunotherapy receives FDA's Breakthrough Therapy designation for ALL treatment

Treating ulcerative colitis and Crohn’s disease

Researchers find novel inhibitor that prevents cholera toxin from binding to carbohydrates

Standard risk factors stratify already high-risk diabetic patients

High level of adiponectin linked to decreased risk of diabetes, cardiovascular disease

CNIOA researchers update number of human genes to 19,000

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

Transcription factor IRF4 plays key role in brown fat's thermogenic process

Plasmonic biosensors: A key asset in personalised medicine

Research: New protein complex fights against bacterial infection that causes gastric cancer

Researchers identify pathogenic mechanism common to several neurodegenerative diseases

Researchers reveal how schizophrenia-linked genetic variation alters skeletons of developing brain cells

Researchers unlock secret behind the activation of Ras proteins

Leading hypothesis for miscarriages, birth defects ruled out by WSU reproductive biologists

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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