Protein News and Research

RSS

Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

CAPE arrests growth of prostate cancer cells and tumors in mice

An over-the-counter natural remedy derived from honeybee hives arrests the growth of prostate cancer cells and tumors in mice, according to a new paper from researchers at the University of Chicago Medicine.

4 May 2012

Affymetrix to acquire eBioscience

Affymetrix, Inc., and eBioscience, Inc., a privately-held San Diego, CA-based company with an industry-leading position in flow cytometry and immunoassay reagents for immunology and oncology research and diagnostics, today announced they have amended their existing definitive agreement dated November 29, 2011 under which Affymetrix will acquire eBioscience.

4 May 2012

Integral Molecular receives U.S. patent for methodology that generates Lipoparticles

Integral Molecular, a leader in membrane protein reagents and services, announces the issuance of a key patent protecting its methodology for generating Lipoparticles, which provide highly-concentrated membrane proteins in their native conformation for antibody and drug discovery applications focused on membrane protein targets such as G protein-coupled receptors (GPCRs), ion channels, and transporters.

4 May 2012

Therapy to halt symptoms in Parkinson's patients

Parkinson's disease, a disorder which affects movement and cognition, affects over a million Americans, including actor Michael J. Fox, who first brought it to the attention of many TV-watching Americans. It's characterized by a gradual loss of neurons that produce dopamine. Mutations in the gene known as DJ-1 lead to accelerated loss of dopaminergic neurons and result in the onset of Parkinson's symptoms at a young age.

3 May 2012

Combination of two mTOR inhibitors stops growth of hepatocellular carcinoma

The combination of two inhibitors of protein mTOR stops the growth of primary liver cancer and destroys tumour cells, according to a study by researchers of the Group of Metabolism and Cancer at Bellvitge Biomedical Research Institute.

3 May 2012

HSPH introduces Obesity Prevention Source website

What is causing the obesity epidemic-and how can we stop and reverse this worldwide weight problem? A new website offers authoritative answers to these pressing questions and sheds light on one of the most challenging public health threats of our time.

3 May 2012

Novel stem cell transplantation holds promise for HIV prevention

UC Davis Health System researchers are a step closer to launching human clinical trials involving the use of an innovative stem cell therapy to fight the virus that causes AIDS.

3 May 2012

NJIT professor receives $340,000 NIH grant to investigate membrane proteins

NJIT Associate Professor Edgardo Farinas has been awarded today a three-year $340,000 National Institutes of Health (NIH) grant to investigate spores as a protein display platform for the directed evolution of membrane proteins.

3 May 2012

Probiodrug AG, collaborators explain interplay of key suspects in Alzheimer’s

Probiodrug AG (Probiodrug), a biotech company developing products for the treatment of neurodegenerative and inflammatory diseases with a particular focus on Alzheimer's disease (AD), today announced its scientists and academics collaborators published seminal findings on the role of pyroglu Aβ in AD pathology in the May 2, 2012 online edition of the journal Nature (DOI: 10.1038/nature11060). The new findings add to the growing body of evidence that pyroglu Aβ plays a crucial role in the initiation of AD. In addition, the research results further elucidate the mechanism by which pyroglu Aβ triggers neuronal toxicity.

3 May 2012

Scientists determine structure of green pigment seen in nitrite-cured bacon, other meats

As with many concerned consumers, a team of University of Oklahoma researchers wondered if the green color sometimes seen in bacon is, in fact, harmful to human health. Recently, these OU scientists took an important first step in answering this question by determining the structure of the green pigment responsible for this 'nitrite burn.'

3 May 2012

Foods rich in omega-3 fatty acids linked with lower blood beta-amyloid levels

A new study suggests that eating foods that contain omega-3 fatty acids, such as fish, chicken, salad dressing and nuts, may be associated with lower blood levels of a protein related to Alzheimer's disease and memory problems.

3 May 2012

PRDM16 transcription co-factor plays a critical role in development of embryonic palate

In the United States, a baby is born with a facial cleft every hour, of every day of the year! Such birth defects result from both gene mutations and environmental insults. PRDM16 is a transcription factor originally described as being aberrantly activated in specific types of leukemia's, and more recently as a master regulator of brown adipose tissue differentiation.

3 May 2012

Study confirms that COX-2 inhibitors predispose people to cardiovascular disease

After nearly 13 years of study and intense debate, a pair of new papers from the Perelman School of Medicine, at the University of Pennsylvania have confirmed exactly how a once-popular class of anti-inflammatory drugs leads to cardiovascular risk for people taking it.

3 May 2012

Arena's first quarter net loss decreases to $29.4 million

Arena Pharmaceuticals, Inc. today reported financial results for the first quarter ended March 31, 2012, and reviewed recent developments.

2 May 2012

Grape-derived compound may prevent neurodegenerative disorders involving tau neuropathology

Researchers at Mount Sinai School of Medicine have gained insight into the mechanism by which a pathological brain protein called tau contributes to the progression of Alzheimer's disease (AD) and other neurodegenerative disorders. This finding, published in the most recent issue of the Journal of Biological Chemistry, may provide the basis for future investigations on how to prevent tau from damaging brain circuits involved in cognitive function.

2 May 2012

Expression of tyrosine kinases may limit effectiveness of agents against sarcomas

To better understand the signaling pathways active in sarcomas, researchers at Moffitt Cancer Center used state-of-the-art mass spectrometry-based proteomics to characterize a family of protein enzymes that act as "on" or "off" switches important in the biology of cancer. The tyrosine kinases they identified, the researchers said, could act as "drivers" for the growth and survival of sarcomas.

2 May 2012

Cell-based test to discover molecules for treatment of ER-positive breast cancer

Cancer Research UK and its commercial arm, Cancer Research Technology have developed a unique test to discover molecules that could lead to potential new treatments for oestrogen receptor (ER)-positive breast cancer.

2 May 2012

Scientists identify how cell architecture changes during formation of gametes

Scientists using high-powered microscopes have made a stunning observation of the architecture within a cell - and identified for the first time how the architecture changes during the formation of gametes, also known as sex cells, in order to successfully complete the process.

2 May 2012

Topline, interim results from Celldex Phase 2b EMERGE study of CDX-011 for advanced breast cancer

Celldex Therapeutics, Inc. today announced that interim, topline results of the Phase 2b EMERGE study of CDX-011 in patients with advanced breast cancer will be presented in a webcast on May 23, 2012. Linda Vahdat, MD, Professor of Medicine, Chief of Solid Tumor Service and Director of the Breast Cancer Research Program at Weill Cornell Medical College and the lead investigator of the EMERGE study, will join Celldex on the webcast to discuss data from the study.

2 May 2012

Sanofi Pasteur announces new quadrivalent influenza vaccine Phase III pediatric data

Sanofi Pasteur, the vaccines division of Sanofi, announced today new Phase III data for its investigational quadrivalent influenza vaccine (QIV) in children 6 months through 8 years of age.

2 May 2012

Protein News and Research

Further Reading

CAPE arrests growth of prostate cancer cells and tumors in mice

Affymetrix to acquire eBioscience

Integral Molecular receives U.S. patent for methodology that generates Lipoparticles

Therapy to halt symptoms in Parkinson's patients

Combination of two mTOR inhibitors stops growth of hepatocellular carcinoma

HSPH introduces Obesity Prevention Source website

Novel stem cell transplantation holds promise for HIV prevention

NJIT professor receives $340,000 NIH grant to investigate membrane proteins

Probiodrug AG, collaborators explain interplay of key suspects in Alzheimer’s

Scientists determine structure of green pigment seen in nitrite-cured bacon, other meats

Foods rich in omega-3 fatty acids linked with lower blood beta-amyloid levels

PRDM16 transcription co-factor plays a critical role in development of embryonic palate

Study confirms that COX-2 inhibitors predispose people to cardiovascular disease

Arena's first quarter net loss decreases to $29.4 million

Grape-derived compound may prevent neurodegenerative disorders involving tau neuropathology

Expression of tyrosine kinases may limit effectiveness of agents against sarcomas

Cell-based test to discover molecules for treatment of ER-positive breast cancer

Scientists identify how cell architecture changes during formation of gametes

Topline, interim results from Celldex Phase 2b EMERGE study of CDX-011 for advanced breast cancer

Sanofi Pasteur announces new quadrivalent influenza vaccine Phase III pediatric data

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News