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Researchers characterize the expression of cardiac proteins during embryonic heart development

Researchers at the UNC School of Medicine, UNC McAllister Heart Institute, and the UNC Lineberger Comprehensive Cancer Center characterized the expression of thousands of cardiac proteins during eight critical stages of embryonic heart development.

6 Jun 2023

Study reveals the role of autophagy in competitive elimination of cancer cells

Elimination of transformed cells that can initiate cancer is necessary to maintain tissue integrity. In a new study, scientists from Tokyo University of Science show how this mechanism is regulated by the cellular process “autophagy.”

30 Sep 2022

Intact autophagic vacuoles found to be indispensable in mediating competitive elimination of cancer cells

19 Sep 2022

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A recent study by scientists at Celentyx Ltd, the University of Birmingham, and the University of Warwick and posted to the bioRxiv* preprint server illustrated a cell-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein attachment assay.

28 Jun 2022

Testes found to be a viral reservoir for SARS-CoV-2 replication

In a recent study posted to the medRxiv* pre-print server, researchers used a suite of methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the testis of patients who died from coronavirus disease 2019 (COVID-19) to gain insights into SARS-CoV-2 tropism inside testis and its impact on male fertility.

13 Feb 2022

New gold-nanoparticle probes for target identification of bioactive small molecules

The development of pharmaceutical treatments is difficult -- clinicians and researchers know a certain drug can regulate particular functions, but they might not know how it actually works.

1 Feb 2021

Breakthrough technology identifies proteins' nearest neighbors on cell surfaces

When corporate partners in the Princeton Catalysis Initiative sat down two years ago with David MacMillan, they presented him with a biological challenge at the heart of potential cancer medicines and other therapeutics: which proteins on a cell's surface touch each other?

5 Mar 2020

SYGNIS AG acquires bioconjugation specialist Expedeon

Expedeon, a specialist provider of bioconjugation products and services, has announced it has been fully acquired by Sygnis AG, for EUR 8 million in cash and 3.5 million in shares.

From Expedeon 16 Apr 2018

Scientists use molecular bait strategy to capture and isolate cancer-prone protein

Scientists from the Center for Self-assembly and Complexity (CSC) successfully isolated a cancer-prone protein by fishing out the proteins using 'molecular bait'.

2 Mar 2017

New research pinpoints specific lncRNA that regulates neural development

Compared to other mammals, humans have the largest cerebral cortex. A sheet of brain cells that folds in on itself multiple times in order to fit inside the skull, the cortex is the seat of higher functions. It is what enables us to process everything we see and hear and think.

4 Jun 2016

New study examines single 'transformer' proteins involved in cancer

A new study led by scientists at The Scripps Research Institute and St. Jude Children's Research Hospital shows how a protein involved in cancer twists and morphs into different structures.

22 Dec 2015

Whitehead Institute scientists discover insidious nature of influenza virus

Revealing influenza's truly insidious nature, Whitehead Institute scientists have discovered that the virus is able to infect its host by first killing off the cells of the immune system that are actually best equipped to neutralize the virus.

21 Oct 2013

Study indicates that RNA translation is dictated by translational hotspots

Protein synthesis in the extensions of nerve cells, called dendrites, underlies long-term memory formation in the brain, among other functions. "Thousands of messenger RNAs reside in dendrites, yet the dynamics of how multiple dendrite messenger RNAs translate into their final proteins remain elusive," says James Eberwine, PhD, professor of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, and co-director of the Penn Genome Frontiers Institute.

27 Sep 2013

Chemical biology researchers to meet at Scientific Oktoberfest in München

The "Scientific Oktoberfest" will be this year's meeting point for some of the internationally most distinguished researchers in the field of Chemical Biology. The so-called "CIPSM Fest of Chemical Biology" will be held from the 15th to the 16th of September in the Department of Chemistry of the Ludwig-Maximilians-Universität (LMU) München.

9 Sep 2011

Kinexus Bioinformatics launches new peptide synthesis facility

Kinexus Bioinformatics Corporation, a world leader in functional proteomics research, announced the launch of a new peptide synthesis facility to provide researchers with the latest in peptide array technologies. These new services will facilitate and expedite access to peptide platforms for innovative approaches to proteomic research and discovery.

16 Mar 2010

How H5N1 virus works

H5N1 influenza, also known as avian influenza, is considered a major global threat to human health, with high fatality rates.

27 Sep 2007