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Longer rest periods between weight-lifting sets could help maximise muscle growth

Researchers from the University of Birmingham have found that extended rest intervals between sets of weight-lifting could help with muscle growth.

4 May 2016

Rapamycin drug could target neural damage linked to Leigh syndrome

Salk Institute scientists showed how an FDA-approved drug boosts the health of brain cells by limiting their energy use. Like removing unnecessary lighting from a financially strapped household to save on electricity bills, the drug--called rapamycin--prolongs the survival of diseased neurons by forcing them to reduce protein production to conserve cellular energy.

27 Apr 2016

Researchers determine 3-D structure of RlmN protein from bacteria

The structure of a bacterial RNA-binding protein has been determined in the act of modifying a molecule of RNA -- an achievement that provides researchers with a unique view of the protein's function in action and could lead to clues that would help in the fight against the development of antibiotic-resistant infections.

22 Apr 2016

Actin filaments may be key to molecular machinery that forms, stores long-term memories

Thank the little "muscles" in your neurons for allowing you to remember where you live, what your friends and family look like and a lot more.

19 Apr 2016

High dosages of antihistamines have dulling effect on genes associated with post-exercise recovery

After vigorous exercise, some 3,000 genes go to work to aid recovery by boosting muscles and blood vessels, but in the presence of high doses of antihistamines almost 27 percent of the gene response is blunted, according to University of Oregon researchers.

15 Apr 2016

Novel way of hitting prostate cancer

Researchers at UC Davis, in collaboration with the other institutions, have found that suppressing the nuclear receptor protein ROR-γ with small-molecule compounds can reduce androgen receptor (AR) levels in castration-resistant prostate cancer and stop tumor growth.

29 Mar 2016

Study shows new RNA letter as regulatory key to control gene expression

DNA, RNA, protein -- the end. Or is it? Until recently, the pattern used to encode genetic information into our cells was considered to be relatively straightforward: four letters (A,G,C,T) for DNA and four (A,G,C,U) for RNA. This equation, however, turned out to be oversimplified -- RNA was holding out.

17 Feb 2016

Researchers discover factor that controls embryonic stem cell development

After a gestation period of around ten months, fawns are born in early summer - when the weather is warm and food is plentiful for the mother. Six months would actually be enough for the embryo's development, but then offspring from mating in the later portion of summer would be born in winter.

17 Feb 2016

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process.

1 Feb 2016

Researchers reveal specific enzyme responsible for sensing energy source that fuels growth of cancer cells

An international research team formed by a University of Cincinnati cancer researcher has shown for the first time that a specific enzyme is responsible for sensing the available supply of GTP, an energy source that fuels the uncontrolled growth of cancer cells. The research underscores the enzyme's potential to become a therapeutic target for future cancer drugs.

11 Jan 2016

ORNL's cell-free protein synthesis system can help save lives of soldiers injured in remote locations

Lives of soldiers and others injured in remote locations could be saved with a cell-free protein synthesis system developed at the Department of Energy's Oak Ridge National Laboratory.

30 Dec 2015

Certain gut bacteria linked to type 2 diabetes, reveal Russian scientists

A group of Russian scientists, including Dr Elena Kostryukova, the Head of the Laboratory of Postgenomic Research in Biology of the Scientific Research Institute of Physical-Chemical Medicine and a researcher at MIPT (Moscow Institute of Physics and Technology), and Maria Vakhitova, an MIPT postgraduate student, has discovered that the presence of certain bacteria in the gut may be linked to the development of type 2 diabetes.

21 Dec 2015

Mitochondrial variation and viable pregnancy: an interview with Dr Elpida Fragouli

Embryos require adequate amounts of energy so that they can successfully progress through each of their cell divisions.

16 Dec 2015

Researchers find new way to prevent or reduce pathologies caused by malformed proteins

Improperly formed proteins can cause a host of serious illnesses, from muscular dystrophy to cystic fibrosis. A question of enormous import in research, beyond the challenge of determining how malformed proteins contribute to specific disease processes, is figuring out ways to prevent or reduce the pathologies they cause.

16 Dec 2015

Researchers devise system to accelerate the process of making life-saving vaccines

Researchers at Brigham Young University have devised a system to speed up the process of making life-saving vaccines for new viruses.

20 Nov 2015

Researchers suggest new way to target cancer protein

For years, scientists have struggled to find a way to block a protein known to play an important role in many cancers. The protein, STAT3, acts as a transcription factor -- it performs the crucial task of helping convert DNA into the RNA instructions used to make new proteins.

19 Nov 2015

Scientists identify mechanism that may help prostate cancer cells escape effects of cancer drugs

Advanced prostate cancer is a disease notoriously resistant to treatment. New research by scientists at Fred Hutchinson Cancer Research Center and the University of California, San Francisco sheds light on a new mode of drug resistance to emerging therapies in metastatic prostate cancer.

18 Nov 2015

Understanding how schizophrenia affects workings of the brain

Stem cells from adult schizophrenia patients form new proteins more slowly than those from healthy people, according to new research.

10 Nov 2015

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Scientists at the University of Cambridge have identified a new property of essential proteins which, when it malfunctions, can cause the build up, or 'aggregation', of misshaped proteins and lead to serious diseases.

31 Oct 2015

Lack of adequate sleep can interfere with fundamental cellular process

Lack of adequate sleep can do more than just make you tired. It can short-circuit your system and interfere with a fundamental cellular process that drives physical growth, physiological adaptation and even brain activity, according to a new study from the University of Tennessee, Knoxville.

30 Oct 2015