Proteome News and Research

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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Study identifies proteins that help provide immunity against HIV among commercial sex workers in Kenya

In a study published Wednesday in the Journal of Proteome Research, researchers from the University of Manitoba, along with participants from Canada's National Microbiology Laboratory and the University of Nairobi, indentified more than 15 proteins in a group of Kenyan commercial sex workers thought to have a natural immunity to HIV, the Winnipeg Free Press reports (Tremain, Winnipeg Free Press, 9/4).

9 Sep 2008

Molecular fingerprint of cocaine addiction revealed

The first large-scale analysis of proteins in the brains of monkeys addicted to cocaine reveals new information on how long-term cocaine use changes the amount and activity of various proteins affecting brain function.

27 May 2008

Salivary diagnostics

Accuracy, convenience, and non-invasiveness are the most critical characteristics for any diagnostic tool.

7 Apr 2008

New tool to identify the molecular signatures of serious diseases

University of Florida chemists are the first to use a new tool to identify the molecular signatures of serious diseases - without any previous knowledge of what these microscopic signatures or "biomarkers" should look like.

1 Apr 2008

Spit in a cup to replace needle pricks

One day soon patients may spit in a cup, instead of bracing for a needle prick, when being tested for cancer, heart disease or diabetes.

26 Mar 2008

Human Proteinpedia, a portal to share human protein data among the scientific community

Today, scientists have access to a large amount of biological information through the Internet.

17 Mar 2008

Novel technique using computer modeling identifies potential side effects of pharmaceuticals

Early identification of adverse effects of drugs before they are tested in humans is crucial in developing new therapeutics, as unexpected effects account for a third of all drug failures during the development process.

12 Dec 2007

New computational technique predicts side-effects of a major cancer drug

Researchers at the University of California San Diego have developed a novel computer technique to search for the side effects of major pharmaceuticals.

29 Nov 2007

First chemical evidence of a sperm recognition system in the oviducts of pigs

Adding another layer of competition to the mating game, scientists are reporting possible biochemical proof that the reproductive system of female mammals can "sense" the presence of sperm and react to it by changing the uterine environment.

19 Nov 2007

Chocoholics ....blame it on bacteria!

The craving chocoholics have for chocolate is according to new research the result of metabolic programming.

16 Oct 2007

Hooked on chocolate? the answer why may lie in your gut

For the first time, scientists have linked the all-too-human preference for a food - chocolate - to a specific, chemical signature that may be programmed into the metabolic system and is detectable by laboratory tests.

15 Oct 2007

Proteins found that could be used to improve diagnosis of hepatocellular carcinoma

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics that they have identified proteins that could be used to improve the diagnosis of hepatocellular carcinoma, the most common type of liver cancer.

8 Oct 2007

Call for EU to launch major project to map out all our proteins

Biologists still have no clear idea how many active genes there are coding for proteins in humans and other organisms, even though for some species the genomes have been completely sequenced.

26 Jul 2007

Powerful proteomics research promises to revolutionize biomedical discovery

Human cells function through the concerted action of thousands of proteins that control their growth and differentiation.

20 Jul 2007

Simple bladder cancer test

University of Florida researchers have identified a set of proteins that appear to signal the presence of bladder cancer, a discovery they hope will lead to a simple, fast and noninvasive test that can detect the disease early.

9 Jul 2007

Role of environmental factors in the development of Parkinson's disease

Scientists at the Buck Institute for Age Research have shown that combining two environmental toxic substances accelerated age-related degeneration in neurons associated with Parkinson's disease (PD) in mice.

27 Jun 2007

Snake venom medication

A chemist at the Vienna University of Technology (TU Vienna) is looking for unusual structures in snake venom and plans to prove their medical effectiveness.

16 Jun 2007

Study finds large number of new proteins implicated in Huntington's disease

Researchers from four organizations have identified more than 200 new proteins that bind to normal and mutant forms of the protein that causes Huntington's disease (HD).

11 May 2007

New dynamic view of protein dynamics

Scientists from the Institute for Research in Biomedicine (IRB Barcelona), the Life Sciences Programme at the Barcelona Supercomputing Center (BSC) and the National Institute for Bioinformatics (INB) have published a provisional "atlas" of the dynamic behaviour of proteins in the prestigious scientific journal, Proceedings of the National Academy of Sciences.

9 Jan 2007

An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling

Using a combination of enzyme activity and metabolite profiling, we determined that this protein-whose function was previously unknown-serves as a key regulator of a lipid signaling network that contributes to cancer," said Benjamin F. Cravatt, a Scripps Research professor and a member of its Skaggs Institute for Chemical Biology who led the study.

20 Oct 2006