Proteome News and Research

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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Investigating Human Disease with Mass Spectrometry-based Proteomics

Dr. Andrew Webb describes how his lab uses mass spectrometry-based techniques to understand the role of post-translational modifications in human disease.

From Bruker Daltonics 3 Apr 2020

Nanoneedle technology licensed for early detection of disease, biomarker discovery

A Boston-based startup company, NanoMosaic LLC, intends to commercialize a high-throughput, high-sensitivity platform for analyte detection developed at Harvard University.

2 Apr 2020

Anteater-like animals are the missing link for coronavirus transmission between bats and humans

As scientists scramble to learn more about the SARS-CoV-2 coronavirus, two recent studies of the virus' genome reached controversial conclusions: namely, that snakes are intermediate hosts of the new virus, and that a key coronavirus protein shares "uncanny similarities" with an HIV-1 protein.

26 Mar 2020

Functioning amyloid found in healthy brain

Scientists from St Petersburg University worked with their colleagues from the St Petersburg branch of the Vavilov Institute of General Genetics.

2 Mar 2020

Defining neurogenic niche proteome helps identify key regulators of neurogenesis

In mammalian adult brains, neural stem cells are only present in few specific parts, so called niches. Only these niches are capable of generating new neurons.

7 Feb 2020

Indivumed and Biognosys partnership aims to enhance proteomics insights

Indivumed, a physician-led, integrated global oncology solution provider, announced today its partnership with Biognosys, a leader in next-generation proteomics solutions.

From Biognosys AG 4 Feb 2020

PhoreMost announces two key appointments to strengthen leadership team

PhoreMost Limited, the UK-based biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, today announced it has made two appointments to strengthen its leadership team, as the Company positions itself for growth.

From PhoreMost 3 Feb 2020

New micro-scale technology holds promise for improved tumor diagnosis

Using a single-needle biopsy and new technology for tumor diagnosis developed by Baylor College of Medicine and the Broad Institute of MIT and Harvard, researchers have been able to provide a more detailed and wider window into cancer biology, tumor type and the mechanisms of response and resistance to therapy than with conventional approaches.

27 Jan 2020

New technology systematically identifies drug targets in living animals

Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases.

21 Jan 2020

SITESEEKER to be used for Otsuka’s therapeutics discovery programs

PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER, in disease-relevant pathways nominated by Otsuka.

From PhoreMost 21 Jan 2020

New whooping cough vaccine needed to protect from emerging superbug strains

Australia needs a new whooping cough vaccine to ensure our most vulnerable are protected from the emergence of superbug strains, new UNSW research has shown.

16 Jan 2020

BPA activates immune response in mice that persists for at least three generations

Some plastic food and beverage containers still contain bisphenol A, which can mimic the hormone estrogen. Although experts say that small amounts of BPA detected in foods are unlikely to cause problems, some people worry that constant low-level exposures could have health effects, especially for developing fetuses, infants and children.

16 Jan 2020

New molecular probe senses the state of proteome in live cells

The folding state of the proteins in live cells often reflect the cell’s general health. Australian scientists have developed a molecular probe that senses the state of the proteome—the entire set of the proteins—by measuring the polarity of the protein environment.

10 Jan 2020

Boehringer Ingelheim to use PhoreMost's SITESEEKER platform in new collaboration

PhoreMost to deploy its SITESEEKER platform to identify novel targets for Boehringer Ingelheim’s discovery programs.

From PhoreMost 7 Jan 2020

Grizzly bears' strategy could help prevent muscle atrophy in humans

Grizzly bears spend many months in hibernation, but their muscles do not suffer from the lack of movement. In the journal "Scientific Reports", a team led by Michael Gotthardt reports on how they manage to do this.

30 Dec 2019

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Researchers have identified a genetic signature with prognostic value for certain kinds of breast cancer. The discovery also contributes to a better understanding of the molecular mechanisms of pathological angiogenesis, the aberrant proliferation of blood vessels that occurs during cancer and other diseases.

17 Dec 2019

New tool gives more reliable and precise results in cancer research

Every cell contains a vast number of proteins, each of which has a specific function, for example as a receptor for another molecule or an enzyme that catalyzes chemical reactions.

16 Dec 2019

Researchers making major inroads into finding the cause of different diseases

Australian researchers are making major inroads into finding the cause of heart disease, Alzheimer's, cancer, diabetes and other diseases after discovering a further 148 proteins affected by oxidative stress in the human body.

12 Dec 2019

Extensive tumor protein analysis reveals potential new players in cancer

Looking to gain a deeper understanding of cancer, a team led by researchers at Baylor College of Medicine conducted an extensive computational analysis of the similarities and differences in the entire set of proteins, called the proteome, of more than 500 cancers from five different tissue sites.

12 Dec 2019

Researchers find another piece of puzzle relating to bird flu viruses

Normally, bird flu viruses do not spread easily from person to person. But if this does happen, it could trigger a pandemic. Researchers from the MDC and RKI have now explained in the journal Nature Communications what makes the leap from animals to humans less likely.

10 Dec 2019