The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.
In a recent study posted to the bioRxiv* pre-print server, researchers characterized the mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 15 (Nsp-15).
In a recent study posted to the bioRxiv*preprint server, researchers evaluated the serum proteomic signatures of long coronavirus disease (COVID) patients.
The Josep Carreras Institute becomes part of the Cancer Proteome project, an international initiative for the study of malignant tumors.
In a new study, a worldwide map of the SARS-CoV-2 genome-associated host proteins was developed by a team of researchers using the identification of RNA-binding protein by MS (ChIRP-MS) technique.
Researchers demonstrated that plasma levels of leucine-rich repeat-containing 15 are a strong indicator of the severity of COVID-19 in patients with end-stage kidney disease.
Researchers have discovered the blood clotting and immune protein pathways that are activated in severe cases of COVID-19 in children, paving the way for earlier diagnosis and more targeted treatments.
A new genetic mapping study led by researchers at the Johns Hopkins Bloomberg School of Public Health traces links between DNA variations and thousands of blood proteins in two large and distinct populations. The results should help researchers better understand the molecular causes of diseases and identify proteins that could be targeted to treat these diseases.
The first longitudinal proteome-wide analysis of antibodies in COVID-19 patients has been performed by researchers from the Beijing Institute of Microbiology and Epidemiology and published in the Journal of Advanced Research.
In a recent study published in the Clinical Infectious Diseases journal, the researchers summarized the perspectives and observations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related adaptive immunity.
In a recent study posted to the bioRxiv* preprint server, the researchers investigated the impact of Bacillus Calmette-Guérin (BCG) vaccine-induced antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein.
This study entailed the integration of multiple-omics datasets to examine the dysregulation in the host splicing mechanism and alteration in protein isoforms among COVID-19 patients.
From the muscle fibers that move us to the enzymes that replicate our DNA, proteins are the molecular machinery that makes life possible.
Researchers study neuroinflammation in the cerebrospinal fluid and serum of patients infected with SARS-CoV-2.
A recent study analyzed the antibody that mediated the COVID-19 vaccine-induced thrombotic thrombocytopenia.
Researchers conducted selective phenotyping of coronavirus disease 2019 -relevant host proteins to facilitate target identification for drug repurposing.
A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.
A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.
Researchers identified and validated multiple linear B-cell epitopes in the SARS-CoV-2 proteomes conserved in humans coronaviruses.
Researchers discovered and optimized cysteine-reactive pyrazoline-based covalent inhibitors for several coronaviruses' Mpro, including SARS-CoV-2.
Researchers defined a novel polynucleotide-based Distinctiveness metric to capture the proteome-level differences of emerging SARS-CoV-2 variants and lineages against all previously identified ones.