The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.
Traumatic brain injuries, whether suffered from a blow on the football field or the battle field, can be devastating, leading to disability and shortened lives.
One of the most intriguing properties of the brain is its means to undergo synaptic plasticity which represents the basis for learning and memory, abilities that severely decline in the case of a dementia.
Our mission is to advance the measurement of human proteins with greater precision, to bring to the world the benefits of absolute molecular specificity when it comes to interrogating proteins at the molecular level.
One of the key challenges of proteomics, the study of all proteins expressed by a cell or organism, is managing to distinguish between molecules that are structurally different yet have the same mass.
A healthy heart beats about two billion times during a lifetime – thanks to the interplay of more than 10,000 proteins. Researchers from the Max Planck Institute of Biochemistry and the German Heart Centre at the Technical University of Munich have now determined which and how many individual proteins are present in each type of cell that occurs in the heart.
I run a core facility for AFM techniques, biological medical applications. My research is focussed on in the interaction of platelets and cancer cells.
Researchers from the University of Wisconsin - Madison evaluated whether one simple addition to the diet - one handful-a-day of sweetened dried cranberries - could positively influence the gut microbiome.
Researchers at the University of California San Diego have developed a genome-scale model that can accurately predict how E. coli bacteria respond to temperature changes and genetic mutations.
A Brazilian study, published in Scientific Reports on October 09, 2017, has identified changes in signaling pathways associated with neural plasticity, inflammation and neurodegeneration triggered by a compound from the family of dimethyltryptamine known as 5-MeO-DMT.
Novartis has joined forces with researchers from the University of California, Berkeley, to develop new technologies for the discovery of next-generation therapeutics, pursuing the vast number of disease targets in cancer and other illnesses that have eluded traditional small-molecule compounds and are considered "undruggable."
Even after years of smoking, the body has a remarkable ability to repair itself. Now in a study appearing in ACS' Journal of Proteome Research, scientists report that certain metabolic changes occur soon after quitting, and these changes could help explain how some ill-effects of smoking might be reversible.
The American Physiological Society will host the "Physiological Bioenergetics: Mitochondria from Bench to Bedside" conference August 27–30 in San Diego. The meeting will bring together cross-disciplinary experts who study the mitochondria, which provide the energy to individual cells.
Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a crucial role in heart development, telling undifferentiated stem cells to form heart tubes and eventually muscle.
Mitochondria, best known for their role as powerhouses of eukaryotic cells, fulfill numerous vital functions. Knowledge about the precise protein composition as well as the functions of individual proteins is essential to understand fundamental processes of cell biology and diseases that are caused by cellular defects.
The Department of Energy's Pacific Northwest National Laboratory is part of a nationwide effort to learn more about the role of proteins in cancer biology and to use that information to benefit cancer patients.
Amid the incredible diversity of living things on our planet, there is a common theme. Organisms need to acquire new genes, or change the functions of existing genes, in order to adapt and survive.
In autoimmune diseases, the immune system wrongly identifies its "enemy", and produces antibodies that attack the patient's own cells.
Autophagy is the recycling process by which our cells keep themselves young. They continually break down and renew small parts of themselves in a kind of self-digestion; this helps to counteract harmful deposits which may form.
COSMIC-3D, the most comprehensive system for exploring cancer mutations in three dimensions, is launched today by COSMIC, based at the Wellcome Trust Sanger Institute, in collaboration with Astex Pharmaceuticals, Cambridge, UK.
Scientists from the Center for Self-assembly and Complexity (CSC) successfully isolated a cancer-prone protein by fishing out the proteins using 'molecular bait'.