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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Study uses MRI imaging to assess the brain matter of WTC responder patients

Two studies led by Stony Brook University researchers to be presented virtually at the Alzheimer's Association International Conference on July 28, 2020, indicate that World Trade Center (WTC) first responders are at risk for developing dementia.

28 Jul 2020

Boehringer Ingelheim and Biognosys join forces on applying quantitative proteomics tools in drug discovery

Biognosys announced today that it started working together with Boehringer Ingelheim.

From Biognosys AG 24 Jul 2020

Analysis of the SARS-CoV-2 proteome via visual tools

Now, a new study published on the preprint server bioRxiv* in July 2020 shows how this can be advanced at a greater speed by combining experimental results with homology models obtained by high-throughput pipelines. This will help produce new hypotheses that will show novel druggable targets for effective drug development.

21 Jul 2020

Scientists explore how scorpion toxin may help treat heart attacks

Scientists are discovering potential life-saving medicines from an unlikely source: the venom of creatures like snakes, spiders and scorpions.

15 Jul 2020

New mass spectrometry-based test detects coronavirus in gargle solutions of patients

Pharmacists at Martin Luther University Halle-Wittenberg have succeeded in detecting small amounts of coronavirus SARS-CoV-2 using mass spectrometry.

15 Jul 2020

Expansion stress promotes aggressive tumor cell growth in breast cancer

Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.

9 Jul 2020

Blood cell damage in COVID-19 may compromise oxygen transport

Researchers in the U.S. have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may alter key protein structures on red blood cells and compromise the transport and delivery of oxygen in patients with coronavirus disease 2019 (COVID-19).

1 Jul 2020

Massive proteomics investigation of COVID-19 infection

Researchers from Germany and Switzerland revealed functional effects of individual severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins on cellular level after infection. They placed the findings into the context of host signaling pathways in order to identify vulnerable parts of the virus amenable to treatment. The study is currently available on the bioRxiv preprint server.

21 Jun 2020

Killifish model helps unravel molecular events that lead to loss of protein homeostasis during brain aging

Aging is the main risk factor for dementia and Parkinson's disease. As age progresses, toxic protein aggregates pile up in the brain and impair neuronal function.

21 Jun 2020

Computational approach to design peptide-based vaccine against SARS-Cov-2

There are currently no licensed vaccines available for COVID-19. While several antiviral drugs have been tested, none has proved to be completely effective against the disease.

11 Jun 2020

Evosep and Agilent Technologies will collaborate to further improve their robust, high-throughput workflows for proteomics

Today, at the ASMS 2020 Reboot, Evosep and Agilent Technologies announce their joint efforts to improve robust, high-throughput workflows for clinical research proteomics.

From Agilent Technologies 10 Jun 2020

New EUbOPEN consortium will enable access to research tools to unlock disease biology

Frankfurt and Ingelheim. Almost twenty years after deciphering the human genome, our understanding of human disease is still far from complete.

8 Jun 2020

High-throughput analysis of blood plasma could help identify biomarkers for ALS

High-throughput analysis of blood plasma could aid in identification of diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis (ALS), according to research from North Carolina State University.

29 May 2020

Thermo Fisher Scientific acknowledges the winners of 2020 TMT Research Grant Award

Thermo Fisher Scientific, the world leader in serving science, recognizes the winners of the 2020 Thermo Scientific Tandem Mass Tag Research Award.