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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Scientists show how T cells may help protect against severe COVID

In a recent study published in the Clinical Infectious Diseases journal, the researchers summarized the perspectives and observations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related adaptive immunity.

25 Apr 2022

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, the researchers investigated the impact of Bacillus Calmette-Guérin (BCG) vaccine-induced antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein.

25 Apr 2022

RNA splicing abnormalities in COVID-19 patients

This study entailed the integration of multiple-omics datasets to examine the dysregulation in the host splicing mechanism and alteration in protein isoforms among COVID-19 patients.

20 Apr 2022

New deep learning neural network model predicts physical interactions of protein complexes

From the muscle fibers that move us to the enzymes that replicate our DNA, proteins are the molecular machinery that makes life possible.

20 Apr 2022

The brain's reaction to COVID's inflammatory tidal wave

Researchers study neuroinflammation in the cerebrospinal fluid and serum of patients infected with SARS-CoV-2.

18 Apr 2022

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

A recent study analyzed the antibody that mediated the COVID-19 vaccine-induced thrombotic thrombocytopenia.

7 Apr 2022

Study investigates targeted phenotyping of host proteins aiding drug repurposing in COVID-19

Researchers conducted selective phenotyping of coronavirus disease 2019 -relevant host proteins to facilitate target identification for drug repurposing.

4 Apr 2022

A summary of SARS-CoV-2 RNA-protein interactome studies

A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.

30 Mar 2022

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.

29 Mar 2022

Identification of linear B cell epitopes in the SARS-CoV-2 proteome that are conserved in humans coronaviruses

Researchers identified and validated multiple linear B-cell epitopes in the SARS-CoV-2 proteomes conserved in humans coronaviruses.

15 Mar 2022

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Researchers discovered and optimized cysteine-reactive pyrazoline-based covalent inhibitors for several coronaviruses' Mpro, including SARS-CoV-2.

11 Mar 2022

Study shows competitive fitness of emerging SARS-CoV-2 variants linked to their distinctiveness relative to identified lineages

Researchers defined a novel polynucleotide-based Distinctiveness metric to capture the proteome-level differences of emerging SARS-CoV-2 variants and lineages against all previously identified ones.

11 Mar 2022

Causal links between severe COVID-19 and blood proteins identified via proteome-wide Mendelian randomization in new study

A recent study was based on Mendelian randomization analyses conducted between high levels of numerous blood proteins and COVID-19.

9 Mar 2022

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

A new study used glycoprotein profiling technology platform that couples high-resolution LC-MS for glycoprotein analysis in regards to COVID-19.

9 Mar 2022

Research sheds light on important events that may play a role in infertility

Everyone considers sperm to be made exclusively by males. But did you know that females also make sperm? Well, it turns out that females also contribute to what makes a sperm a sperm.

8 Mar 2022

Scientists shed light on placenta's role in transferring vitamin D to fetus during pregnancy

Scientists have shed new light on the role of the placenta in managing the relationships between maternal vitamin D and fetal development, according to a study published today in eLife.

8 Mar 2022

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

A recent study assessed neutrophil extracellular trap formation and antiviral host response in high-risk COVID-19 patients.

8 Mar 2022

Study provides new insights into the communication of bacteria with their host

A newly discovered protein helps bacteria recognize stress hormones in the human body and direct their motion in the host.

7 Mar 2022

Blood groups play a key role in whether people develop severe COVID-19, study suggests

A new study has analyzed over 3000 proteins to identify which are causally linked to the development of severe COVID-19.

3 Mar 2022

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Multiple myeloma (MM) is a largely incurable cancer of plasma cells with an extremely poor prognosis. However, investigators from Japan have recently found that a common component of amino acid transporters, CD98 heavy chain, represents an effective monoclonal antibody target in treating MM.

22 Feb 2022

Proteome News and Research

Scientists show how T cells may help protect against severe COVID

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

RNA splicing abnormalities in COVID-19 patients

New deep learning neural network model predicts physical interactions of protein complexes

The brain's reaction to COVID's inflammatory tidal wave

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

Study investigates targeted phenotyping of host proteins aiding drug repurposing in COVID-19

A summary of SARS-CoV-2 RNA-protein interactome studies

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

Identification of linear B cell epitopes in the SARS-CoV-2 proteome that are conserved in humans coronaviruses

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Study shows competitive fitness of emerging SARS-CoV-2 variants linked to their distinctiveness relative to identified lineages

Causal links between severe COVID-19 and blood proteins identified via proteome-wide Mendelian randomization in new study

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

Research sheds light on important events that may play a role in infertility

Scientists shed light on placenta's role in transferring vitamin D to fetus during pregnancy

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

Study provides new insights into the communication of bacteria with their host

Blood groups play a key role in whether people develop severe COVID-19, study suggests

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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