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Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

In a new study, researchers evaluated the ability of vaccine-induced antibodies to recognize and neutralize various SARS-CoV-2 variants of concern in SARS-CoV-2-naive health care workers in the Netherlands.

19 May 2022

Recombinant protein vaccine stands up to SARS-CoV-2 variants

A study by researchers in Texas describes a mouse model in which a subunit vaccine with alum-CpG adjuvant was tested for its ability to induce a broadly neutralizing antibody response against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 May 2022

Study explores lipid nanoparticles against SARS-CoV-2

Researchers assessed the efficiency of lipid nanoparticles against SARS-CoV-2.

18 May 2022

Compound found in Datura shows promise as antiviral agent against SARS-CoV-2

Researchers from Naval Medical University have been investigating anisodamine, used in traditional Chinese medicine, to inhibit SARS-CoV-2 infection in cellular models. The study is published in the journal Biochemical and Biophysical Research Communications.

17 May 2022

3rd dose of COVID mRNA vaccine expands memory and capacity of immune system to combat Omicron

Researchers from the United States have now found that the immune recall induced by a two-dose primary series of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination after an initial natural infection highly improves the longevity of the antibodies as well as induces an enhanced breadth of protection across the SARS-CoV-2 variants.

17 May 2022

Triple vaccination found to confer immune protection against SARS-CoV-2 Omicron BA.2 sublineage

Researchers assessed the immune responses induced by two doses or three doses of the BNT162b2 (BNT) or the CoronaVac (CorV) vaccine against SARS-CoV-2 Omicron BA.2 sublineage among public servants working for the government of Hong Kong.

16 May 2022

Delta- and Omicron BA.1-variant specificity of B cell repertoires established by an initial Wuhan strain infection

Researchers performed an unbiased evaluation of the early memory B cell repertoire specific for the Omicron and Delta variants of SARS-CoV-2.

12 May 2022

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* preprint server, researchers reported that nanoparticles could prevent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cell entry.

10 May 2022

mRNA boosters enhance neutralization of SARS-CoV-2 BA.1, BA.2 and BA.3

A study recently published in the journal Cell Host & Microbe has described that all three sublineages of the omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit similar host cell entry efficiency and are neutralized equally by antibodies generated in response to coronavirus disease 2019 (COVID-19) booster vaccination

10 May 2022

Infection with SARS-CoV-2 results in antibodies against common colds

A study published in the journal Science Advances uses electron microscopy-based polyclonal epitope mapping (EMPEM) methodology to elucidate the spike epitopes of β-HCoV targeted by preexisting serum antibodies and compares them to the epitopes targeted by antibodies elicited by SARS-CoV-2 infection using electron microscopy-based polyclonal epitope mapping (EMPEM) methodology.

8 May 2022

Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

In a recent study posted to the Research Square* preprint server, researchers tested the safety and immunogenicity of a third dose of coronavirus disease 2019 (COVID-19) prototype messenger ribonucleic acid (mRNA)-1273 versus a variant vaccine and a bivalent vaccine formulation.

5 May 2022

SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

A recent study posted to the bioRxiv* preprint server demonstrated that the latest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages evade immunity imparted by the prior subvariants.

5 May 2022

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

Researchers determined the threshold neutralizing antibody titer for effective COVID-19 convalescent plasma therapy.

4 May 2022

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

A new study analyzed multivalent messenger ribonucleic acid (mRNA)-lipid nanoparticle (LNP) vaccine constructs against certain β-coronaviruses (β-CoVs).

3 May 2022

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

In a new study, researchers described their self-designed chimeric receptor-binding domain-dimer vaccine approach to adapt SARS-CoV-2 variants of concern and variants of interest.

29 Apr 2022

Study shows polysaccharides of seaweed and abalone inhibit SARS-CoV-2 in vitro

A new study published in Marine Drugs evaluated the inhibitory effect of three polysaccharides, crude polysaccharide from Hizikia fusiforme (CPHF), crude polysaccharide from Sargassum horneri (CPSH), and crude polysaccharide from abalone viscera (CPAV) on the propagation of SARS-CoV-2 in vitro.

28 Apr 2022

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

A new paper describes a novel method, using a specific molecule to engage T cell receptors and the virus receptor, the angiotensin-converting enzyme 2, at the same time.

28 Apr 2022

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Researchers identified a human monoclonal antibody (mAb), 87G7, with in vitro neutralizing activity against several SARS-CoV-2 VOCs, including Alpha, Beta, Gamma, Delta, and Omicron.

28 Apr 2022

Discovery of novel antibody that targets shared epitope on SARS-CoV-2 variants

Researchers assessed the antibody responses elicited by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and defined the epitopes shared by them.

28 Apr 2022

Nanobody effectively neutralizes pseudotyped ancestral SARS-CoV-2 and Omicron spike proteins

Researchers identified a nanobody inhibiting SARS-CoV-2 variants.

26 Apr 2022

Pseudovirus News and Research

Neutralizing antibody responses induced by COVID-19 vaccines against SARS-CoV-2 variants

Recombinant protein vaccine stands up to SARS-CoV-2 variants

Study explores lipid nanoparticles against SARS-CoV-2

Compound found in Datura shows promise as antiviral agent against SARS-CoV-2

3rd dose of COVID mRNA vaccine expands memory and capacity of immune system to combat Omicron

Triple vaccination found to confer immune protection against SARS-CoV-2 Omicron BA.2 sublineage

Delta- and Omicron BA.1-variant specificity of B cell repertoires established by an initial Wuhan strain infection

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

mRNA boosters enhance neutralization of SARS-CoV-2 BA.1, BA.2 and BA.3

Infection with SARS-CoV-2 results in antibodies against common colds

Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

Multivalent messenger ribonucleic acid-lipid nanoparticle vaccines against SARS-CoV-2

Chimeric Delta-Omicron RBD-dimer vaccine found to be effective against SARS-CoV-2 variants

Study shows polysaccharides of seaweed and abalone inhibit SARS-CoV-2 in vitro

Therapeutic promise of CAR-T cell bispecific engagers against SARS-CoV-2

Identification of a SARS-CoV-2 neutralizing human monoclonal antibody with a remarkable broad-spectrum neutralization and protection efficacy

Discovery of novel antibody that targets shared epitope on SARS-CoV-2 variants

Nanobody effectively neutralizes pseudotyped ancestral SARS-CoV-2 and Omicron spike proteins

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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