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New method to monitor activity of gene promoters during response to drug

When developing new drugs, monitoring cellular responses to candidate compounds is essential for assessing their efficacy and safety. Researchers from the RIKEN Center for Life Science Technologies report a new method to monitor and quantify the activity of gene promoters during the response to a drug, using the advanced gene expression analysis method CAGE followed by single-molecule sequencing.

3 Oct 2013

Tri-linear interpolation algorithm can achieve cerebral white matter fiber reliable tracking

At present, fiber tracking algorithms are divided into deterministic tractography and probabilistic tractography. In deterministic algorithms, scholars proposed the fiber assignment by continuous tracking algorithm, the tensor deflection algorithm, the tensorline algorithm.

11 Sep 2013

Increased flexibility in live cell imaging offered by Olympus’ new advanced optical modules in its inverted microscope frame design

Extending the capabilities of the fully customisable IX3 inverted microscope frame, Olympus has expanded its range of compatible, interchangeable optical modules. Ease-of-use and accuracy are vastly improved via new motorised components, which also present a cost-efficient means to gradually upgrade to a fully motorised microscope system.

From Evident Corporation - Life Sciences 20 Aug 2013

Toshiba to showcase new cardiovascular ultrasound systems at ASE annual meeting

To improve exam efficiency and increase accuracy of cardiovascular disease diagnoses, Toshiba America Medical Systems, Inc. will showcase its AplioTM 500 CV, 300 CV and ArtidaTM ultrasound systems at this year's American Society of Echocardiography annual meeting in Minneapolis, June 29 - July 2, 2013 (Booth #415).

28 Jun 2013

Hypometabolism in brain regions of cognitively normal patients associated with Alzheimer's disease

Alzheimer's disease has been linked in many studies to amyloid plaque buildup in the brain, but new research is finding a common thread between amyloid burden and lower energy levels, or metabolism, of neurons in certain areas of the brain associated with Alzheimer's disease-even for people with no sign of cognitive decline.

12 Jun 2013

Toshiba partners with leading institutions to conduct Athlete Heart Research Study

Sudden cardiac death is the leading cause of death in high school-aged athletes. To determine if SCD can be prevented with a heart screening, The Christ Hospital Health Network (Cincinnati, Ohio), The University of Mississippi Medical Center and Cincinnati Children's Hospital Medical Center partnered with USRowing and Toshiba America Medical Systems, Inc. to conduct The Athlete Heart Research Study.

12 Jun 2013

Powerful new mass spectrometry systems and solutions for life-science research, clinical research, pharma and applied markets announced by Bruker

At the 61st ASMS Conference on Mass Spectrometry and Allied Topics, Bruker today announced mass spectrometry-based product introductions for life-science and clinical research, for biotech/pharma/CRO customers, as well as for industrial and applied markets. The new mass spectrometry systems and solutions are designed to deliver confident analyses with dramatically enhanced resolution, sensitivity and precision.

10 Jun 2013

World’s first “Tribrid” LC-MS launched by Thermo Fisher Scientific

Thermo Fisher Scientific Inc., the world leader in serving science, introduced the Thermo Scientific Orbitrap Fusion Tribrid liquid chromatography-mass spectrometry (LC-MS) system, combining its three mass analyzers –quadrupole, Orbitrap and linear ion trap – in a novel “Tribrid” architecture that offers unprecedented depth of analysis of complex biological samples.

From Thermo Fisher Scientific Inc. 10 Jun 2013

KLAS awards top rankings to Toshiba’s Aplio 500 CV cardiac ultrasound system

Toshiba America Medical Systems, Inc.'s Aplio 500 CV cardiac ultrasound system was ranked as the top performer in KLAS' "Echocardiography 2013: 2D or not 2D?" report. Toshiba received top scores in 18 out of 25 attributes.

29 May 2013

Drug resistant brain tumors: an interview with Prof. Mischel, Ludwig Institute for Cancer Research and Prof. Bensinger, University of California

In cancer, mutations in proteins that control cell growth are common, leading to unrestrained cellular proliferation and tumor formation.

9 May 2013

Luminex's MAGPIX instrument gets FDA approval

Luminex Corporation today announced it has received U.S. FDA clearance of its MAGPIX instrument, with its xTAG Gastrointestinal Pathogen Panel.

From Luminex 16 Apr 2013

Mammalian target of rapamycin (mTOR) pathway: an interview with Dr. Paul Mischel, Ludwig Institute for Cancer Research

The mammalian target of rapamycin, mTOR is a central integrator of the cell that coordinates growth factor receptor signaling with energy and nutrient status to control a wide array of activities, including the regulation of cellular proliferation and survival.

9 Apr 2013

V/Q imaging can detect early stages of COPD

In vivo ventilation/perfusion (V/Q) imaging can detect early changes to the lung caused by cigarette smoke exposure and provides a noninvasive method for studying lung dysfunction in preclinical models, according to research published in the April issue of The Journal of Nuclear Medicine.

2 Apr 2013

Bruker introduces new products with scientific capabilities for research, industrial and applied markets

At Pittcon 2013, Bruker today announced numerous new product introductions for research, industrial and applied markets, designed to deliver more confident analyses with increased sensitivity, specificity and productivity, as well as novel scientific capabilities which expand the boundaries of molecular and materials research.

19 Mar 2013

Toshiba introduces Aplio 500 and 300 CV ultrasound systems

To help clinicians more accurately and efficiently diagnose cardiovascular disease, Toshiba America Medical Systems, Inc. introduces the Aplio 500 and Aplio 300 CV ultrasound systems.

8 Mar 2013

Prostate tissue androgen content predicts ADT outcome

Determining the androgen content in prostate tissue could predict patients’ responses to androgen deprivation therapy and the risk for castration-resistant prostate cancer, show study findings.

6 Mar 2013

Microcystins in drinking water

An interview with Rohan Thakur, discussing the prevalence of microcystins in drinking water, and the use of LC-MS to identify cyanotoxins within water samples.

From Bruker Life Sciences Mass Spectrometry 5 Mar 2013

Researchers create new ultra-sensitive tool for chemical, DNA and protein analysis

Utilizing optical characteristics first demonstrated by the ancient Romans, researchers at the University of Illinois at Urbana-Champaign have created a novel, ultra-sensitive tool for chemical, DNA, and protein analysis.

16 Feb 2013

Extramacular scanning shows promise in uveitic disorders

New optical coherence tomography scanning protocols offer enhanced characterization of patients with birdshot chorioretinopathy, UK researchers report.

25 Jan 2013

New math model may help predict colon cancer resistance to chemotherapy

Scientists may be able to better predict which patients with colorectal cancer will respond to chemotherapy using a new mathematical model that measures the amount of stress required for a cancer cell to die without harming healthy tissue. The results of this study are published in Cancer Research, a journal of the American Association for Cancer Research.

19 Jan 2013