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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Improved Cas9 enzyme reduces chance of off-target CRISPR mutations

Genomics experts have discovered that when guide RNAs (gRNA) are designed properly, the risk of off-target mutations induced by the cas9 enzyme is very rare.

30 Oct 2019

DNA sequences encode information in many different ways

DNA sequences encode information in many different ways. Codons specify the amino acids involved in making a protein.

30 Oct 2019

Dynamic molecular signaling waves control embryonic fates

Timing is everything for young cells waiting to determine their identities.

29 Oct 2019

Researchers reconstruct the evolutionary history of metabolism

By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks - which drive every cellular process from protein building to DNA repair - became less random, more modular and more hierarchical over time, the researchers say.

29 Oct 2019

How the SETD1A gene produces schizophrenia in mice

A new study published in the journal Neuron on October 9, 2019 reports that scientists have unlocked part of the secrets of the SETD1A gene – how mutations in the gene put the individual at risk for the condition.

26 Oct 2019

Ultraviolet B light is good for the gut microbiome

A small study published in the journal Frontiers in Immunologyon October 24, 2019, shows that exposure to ultraviolet B (UVB) light, which is commonly achieved through sunlight exposure, can trigger specific beneficial changes in the gut microbiome, which are dependent on the preceding serum levels of vitamin D.

24 Oct 2019

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

A new study by Weill Cornell Medicine and Cornell University has come up with more explanations of how gut microbes communicate with the brain neurons. The study, published in the journal Nature on October 23, 2019, examined the brains of mouse models and found that when the gut microbiome is significantly reduced, there are changes in gene expression in the brain’s microglial cells.

24 Oct 2019

Cooperative research center at LLNL aims to develop vaccines for chlamydia

A cooperative research center that aims to develop vaccines for chlamydia has been established by the National Institutes of Health at Lawrence Livermore National Laboratory.

24 Oct 2019

Molecular processes underlying communication between gut microbes and brain cells revealed

New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine and Cornell's Ithaca campus.

23 Oct 2019

Emory researchers awarded NIAID contract to develop better drug against influenza

With the flu killing an average of 20,000 people annually in the United States and posing the larger threat of global pandemics, Emory University's strides in influenza research carry the hope of saving lives here and abroad.

23 Oct 2019

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

A research team from the School of Chinese Medicine at Hong Kong Baptist University has successfully developed a novel aptamer, i.e. a single-stranded piece of DNA, for the treatment of osteogenesis imperfecta (OI) with the aid of artificial intelligence (AI) technology.

23 Oct 2019

CELLINK’s I-DOT can facilitate genetic cancer diagnostic research, study shows

New research from the Karolinska Institute has demonstrated the I-DOT’s capability to facilitate genetic research in cancer diagnostics. The Karolinska Institute in Sweden is at the forefront of cancer research in the world.

23 Oct 2019

LSU Health New Orleans awarded $1.74 million to advance research on Usher syndrome

Jennifer J. Lentz, PhD, Associate Professor at LSU Health New Orleans Neuroscience Center of Excellence and Departments of Otorhinolaryngology, Genetics and Ophthalmology, in collaboration with Robert K. Koenekoop MD, PhD and Professor of Pediatric Surgery, Human Genetics and Ophthalmology at McGill University in Montreal, Quebec, Canada, has been awarded a $1.74 million USD grant to advance research on Usher syndrome.

22 Oct 2019

Dual action of genes and RNA influences aggressive triple-negative breast cancer

Women with an aggressive, less-common type of breast cancer, known as triple-negative, versus a more common form of the disease, could be differentiated from each other by a panel of 17 small RNA molecules that are directly influenced by genetic alterations typically found in cancer cells.

22 Oct 2019

Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

Despite advances in cancer survival, more than 90 percent of people with pancreatic cancer die within five years. Most patients with pancreatic tumors (and half of those with colorectal cancers) carry a mutation in the KRAS gene, which normally controls cell growth and death.

21 Oct 2019

Patterns unique to the striatum observed in people with Huntington's disease

The part of the brain that selectively degenerates in people with Huntington's disease (HD), called the striatum, is almost entirely destroyed in the late stages of the disease. Brain samples from mutant HD gene positive individuals who had not yet developed symptoms by time of death are extremely rare. As a consequence, very little is known about the active disease process that causes the devastating symptoms of HD.

21 Oct 2019

Study shows link between high-fat diet and earlier appearance of Alzheimer's markers in the brain

Once it begins, Alzheimer's disease progresses systematically and aggressively, attacking victims on multiple fronts. But scientists studying the disease operate the same way - like Kent State University's own Gemma Casadesus Smith, Ph.D.

17 Oct 2019

Rare sex-specific brain cells found in male and female mice

Caltech researchers have discovered rare brain cell types that are unique to male mice and other types that are unique to female mice. These sex-specific cells were found in a region of the brain that governs both aggression and mating behaviors.

17 Oct 2019

Study: High levels of circ E7 is a positive prognostic marker in anal squamous cell carcinoma

High levels of circ E7 by quantitative RT-PCR predicted improved overall survival in ASCC and analysis of The Cancer Genome Atlas sequencing from HPV-positive head and neck cancer and cervical cancer suggested high circ E7 marked improved survival in 875 subjects.

17 Oct 2019

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Subtle changes in the DNA of mitochondria, the tiny power plants within cells, can have profound consequences for a patient's health.

16 Oct 2019

RNA News and Research

Further Reading

Improved Cas9 enzyme reduces chance of off-target CRISPR mutations

DNA sequences encode information in many different ways

Dynamic molecular signaling waves control embryonic fates

Researchers reconstruct the evolutionary history of metabolism

How the SETD1A gene produces schizophrenia in mice

Ultraviolet B light is good for the gut microbiome

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

Cooperative research center at LLNL aims to develop vaccines for chlamydia

Molecular processes underlying communication between gut microbes and brain cells revealed

Emory researchers awarded NIAID contract to develop better drug against influenza

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

CELLINK’s I-DOT can facilitate genetic cancer diagnostic research, study shows

LSU Health New Orleans awarded $1.74 million to advance research on Usher syndrome

Dual action of genes and RNA influences aggressive triple-negative breast cancer

Peptide-based nanoparticles can suppress pancreatic cancer growth without adverse effects

Patterns unique to the striatum observed in people with Huntington's disease

Study shows link between high-fat diet and earlier appearance of Alzheimer's markers in the brain

Rare sex-specific brain cells found in male and female mice

Study: High levels of circ E7 is a positive prognostic marker in anal squamous cell carcinoma

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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