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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study shows impacts of ASO-based MALAT1-inhibition on MAPK-pathway gene regulation in melanoma

A new research paper was published in Oncotarget's Volume 14 on May 26, 2023, entitled, "Deconstructing the role of MALAT1 in MAPK-signaling in melanoma: insights from antisense oligonucleotide treatment."

30 May 2023

Hydrogen inhalation provides a potential protective strategy for astronauts' brain health

Astronauts are affected by various physical and chemical factors during spaceflight, resulting in a series of pathological and physiological changes.

30 May 2023

Alternative gene splicing can impact the risk for alcohol use disorder

Researchers at Indiana University School of Medicine have discovered alternative gene splicing, which occurs during gene expression, can impact a person's risk of alcohol use disorder (AUD).

30 May 2023

RNA plays a role in regulating cell fate in the early mouse embryo

The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments.

30 May 2023

Mental health profoundly impacts inflammatory responses in the body

Study uncovered mechanisms by which psychological stress affects bowel inflammation.

30 May 2023

New pan-cancer T cell atlas provides a deeper understanding of complex tumor microenvironment

A new study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, provides a deeper understanding of the vast diversity of T cell states as well as their relationships and roles within the complex tumor microenvironment, bringing a fresh perspective to understanding immunotherapy efficacy in cancer.

29 May 2023

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

The Pediatric Cancer Research Foundation, a nonproﬁt focused on transforming pediatric cancer care by accelerating research breakthroughs, today announced the 19 recipients of its 2023 research grants.

26 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

How do the outcomes of viral coinfections vary across host species?

In a recent study published in the journal PLOS Pathogens, researchers investigated the outcomes of coinfections of two viruses — Drosophila C Virus (DCV) and Cricket Paralysis Virus (CrPV) in 25 inbred lines of Drosophila melanogaster and 47 other host species belonging to the Drosophilidae family.

26 May 2023

New review unravels phthalates’ role in heart disease

Researchers review existing data on the impact of phthalate exposure on cardiovascular health.

25 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

First systematic single-cell analysis of transcriptional variation within the T cell population

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Immune cells play important roles in mediating allograft rejection and tolerance after cardiac transplantation.

25 May 2023

Study examines the role of genetic variants across diverse ancestries in regulating gene expression

Exploring diverse ancestry is a critical factor in furthering medical research.

25 May 2023

Immune cells targeting core protein play an important role in early immune defense against COVID-19

LMU immunologists have studied the early immune response to acute SARS-CoV-2 infection and show how vaccines could be improved in future.

25 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Targeted protein degradation uses different types of "degrading" drugs (degraders) to force proximity between a target protein (for example, a mutated protein that contributes to the development of a disease) and the cellular machinery that directs protein degradation.

23 May 2023

Surviving without glucose: uridine-derived ribose as an alternative energy source

Researchers attempted to identify new genes and molecular pathways that might supply energy when the availability of glucose or other nutrients is limited.

22 May 2023

RNA News and Research

Further Reading

Study shows impacts of ASO-based MALAT1-inhibition on MAPK-pathway gene regulation in melanoma

Hydrogen inhalation provides a potential protective strategy for astronauts' brain health

Alternative gene splicing can impact the risk for alcohol use disorder

RNA plays a role in regulating cell fate in the early mouse embryo

Mental health profoundly impacts inflammatory responses in the body

New pan-cancer T cell atlas provides a deeper understanding of complex tumor microenvironment

2023 PCRF grant recipients announced for exploring new, safer treatments for pediatric cancers

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

How do the outcomes of viral coinfections vary across host species?

New review unravels phthalates’ role in heart disease

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

First systematic single-cell analysis of transcriptional variation within the T cell population

Study examines the role of genetic variants across diverse ancestries in regulating gene expression

Immune cells targeting core protein play an important role in early immune defense against COVID-19

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

The adaptive immunity of human endemic viruses

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Surviving without glucose: uridine-derived ribose as an alternative energy source

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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