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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Alnylam advances Development Candidate for ALN-AS1 for treatment of hepatic porphyrias

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that it is advancing its Development Candidate for ALN-AS1, an RNAi therapeutic targeting aminolevulinate synthase-1 (ALAS-1) for the treatment of hepatic porphyrias including acute intermittent porphyria (AIP).

9 Oct 2013

Arrowhead initiates Phase 1 study of ARC-520 for treatment against chronic HBV infection

Arrowhead Research Corporation (NASDAQ: ARWR), a biopharmaceutical company developing targeted RNAi therapeutics, today announced that it completed enrollment in a Phase 1 clinical trial of ARC-520, its RNAi-based candidate against chronic hepatitis B virus infection.

9 Oct 2013

Researchers who contributed to field of medicine receive Keio Medical Science Prize

The 18th Keio Medical Science Prize has been awarded to Victor R. Ambros, PhD, professor of molecular medicine at the University of Massachusetts Medical School and the Silverman Chair in Natural Science; and Shigekazu Nagata, PhD, professor of medical chemistry in the Graduate School of Medicine at Kyoto University.

8 Oct 2013

Professor receives $1.3M EUREKA grant to explore communication between cytoplasm and nucleus

University of Massachusetts Medical School Professor and Vice Chair of Neurobiology Vivian Budnik, PhD, has received a four-year, $1.3 million EUREKA (Exceptional Unconventional Research Enabling Knowledge Acceleration) grant from the National Institute of Neurological Disorders and Stroke to explore a novel mechanism of communication between the cytoplasm and the nucleus, called nuclear envelope budding, that may lead to new understandings for various tissue dystrophies and aging disorders.

8 Oct 2013

Smoking during pregnancy may affect child’s immune system on molecular level

The Leipzig Helmholtz Center for Environmental Research has gained new insights on the influence of tobacco smoke in utero. For the first time, it could be demonstrated with smoking pregnant women and their children, how exposure to tobacco smoke affects the development of human immune system on molecular level.

8 Oct 2013

Researchers discover how cancer development molecule maintains its genome integrity

University of Montreal researchers have discovered how telomerase, a molecule essential for cancer development, is directed to structures on our genome called telomeres in order to maintain its integrity and in turn, the integrity of the genome.

7 Oct 2013

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

Investigators at The Feinstein Institute for Medical Research have discovered a protein in the human body that can trigger and mediate inflammation in patients suffering from hemorrhage and sepsis. The findings were published in the online version of Nature Medicine on October 6, 2013.

7 Oct 2013

New injection device delivers optimum treatment dose to hepatitis C patients

A new injection device, ViraferonPeg Clearclick, has launched in the UK today for hepatitis C patients to accurately titrate and self-administer their weekly dose of ViraferonPeg (peginterferon alfa-2b).

5 Oct 2013

Researchers discover way to use stem cells as drug delivery vehicles

A group of Brigham and Women's Hospital, and Harvard Stem Cell Institute researchers and collaborators at MIT and MGH have found a way to use stem cells as drug delivery vehicles.

5 Oct 2013

Cholesterol-lowering drugs could be alternative treatment for people who take statins

A new class of cholesterol-lowering drugs that target a recently discovered regulator of harmful cholesterol could be an alternative or complementary treatment for the 30 million people who take statins, after the first trial in humans confirms the technique’s feasibility and safety.

4 Oct 2013

Harvard University receives $3.5M grant to develop super-resolution microscopy technique

A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has been awarded a special $3.5 million grant from the National Institutes of Health (NIH) to develop an inexpensive and easy-to-use new microscopy method to simultaneously spot many tiny components of cells.

4 Oct 2013

J&J's Janssen Companies Launch A Trio Of Collaborations

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3 Oct 2013

CureVac collaborates with Janssen on development of influenza vaccine based on mRNA

CureVac, a clinical stage biopharmaceutical company that has pioneered the development of a new class of therapies and vaccines based on messenger RNA (mRNA), today announced that it has entered into a collaboration and licensing agreement with Janssen Pharmaceuticals, Inc. Under the agreement CureVac will collaborate with Crucell Holland B.V. (a member of the Janssen Pharmaceutical Companies) on the development of an influenza vaccine based on CureVac's RNActive® technology.

3 Oct 2013

New agreement to expand scope of research project to evaluate MCT-485 for primary liver cancer

MultiCell Technologies, Inc. is pleased to announce the signing of a new sponsored research agreement with Anand Ghanekar, M.D., Ph.D, of the University Health Network's Toronto General Hospital expanding the scope of the research project to evaluate MCT-485 in animal models for the treatment of primary liver cancer.

2 Oct 2013

Moderna Therapeutics Scores Up To $25M DARPA Grant

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2 Oct 2013

Genetic discovery could take guesswork out of prescribing correct dose of drugs

The discovery of genetic differences affecting up to a third of the population could take the guesswork out of prescribing the correct dose of 25 percent of drugs currently on the market, researchers say.

2 Oct 2013

Sister stem cells display considerable differences despite having identical DNA

Scientists have used a brand new technique for examining individual stem cells to uncover dramatic differences in the gene expression levels - which genes are turned 'up' or 'down'- between apparently identical 'sister' pairs.

27 Sep 2013

Scientists unravel secrets of mechanism that snips our genes

Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.

27 Sep 2013

Study indicates that RNA translation is dictated by translational hotspots

Protein synthesis in the extensions of nerve cells, called dendrites, underlies long-term memory formation in the brain, among other functions. "Thousands of messenger RNAs reside in dendrites, yet the dynamics of how multiple dendrite messenger RNAs translate into their final proteins remain elusive," says James Eberwine, PhD, professor of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, and co-director of the Penn Genome Frontiers Institute.

27 Sep 2013

New hepatitis virus reported by scientists was a false alarm

The report by scientists of a new hepatitis virus earlier this year was a false alarm, according to UC San Francisco researchers who correctly identified the virus as a contaminant present in a type of glassware used in many research labs.

27 Sep 2013

RNA News and Research

Further Reading

Alnylam advances Development Candidate for ALN-AS1 for treatment of hepatic porphyrias

Arrowhead initiates Phase 1 study of ARC-520 for treatment against chronic HBV infection

Researchers who contributed to field of medicine receive Keio Medical Science Prize

Professor receives $1.3M EUREKA grant to explore communication between cytoplasm and nucleus

Smoking during pregnancy may affect child’s immune system on molecular level

Researchers discover how cancer development molecule maintains its genome integrity

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

New injection device delivers optimum treatment dose to hepatitis C patients

Researchers discover way to use stem cells as drug delivery vehicles

Cholesterol-lowering drugs could be alternative treatment for people who take statins

Harvard University receives $3.5M grant to develop super-resolution microscopy technique

J&J's Janssen Companies Launch A Trio Of Collaborations

CureVac collaborates with Janssen on development of influenza vaccine based on mRNA

New agreement to expand scope of research project to evaluate MCT-485 for primary liver cancer

Moderna Therapeutics Scores Up To $25M DARPA Grant

Genetic discovery could take guesswork out of prescribing correct dose of drugs

Sister stem cells display considerable differences despite having identical DNA

Scientists unravel secrets of mechanism that snips our genes

Study indicates that RNA translation is dictated by translational hotspots

New hepatitis virus reported by scientists was a false alarm

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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