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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Achillion Pharmaceuticals to present clinical study data of ACH-1625 at APASL 2011

Achillion Pharmaceuticals, Inc. today announced that data from the Company's ongoing clinical studies of ACH-1625 has been accepted for presentation at the 21st Annual Conference of the Asian Pacific Association for the Study of the Liver to be held February 17-21, 2011 in Bangkok, Thailand.

6 Dec 2010

Exiqon announces launch of 6th generation of miRCURY LNA microRNA Arrays

Exiqon A/S, a leading supplier of high-value gene expression analysis products, today announced the launch of the 6th generation of miRCURY LNA microRNA Arrays for expression profiling of microRNA from human, mouse and rat.

6 Dec 2010

Asuragen, Novartis to develop ARQ BCR-ABL1 RNA IS Calibrators, laboratory software reporting tools

Asuragen, Inc. announced today that it has entered into an exclusive agreement with Novartis to develop worldwide Armored RNA Quant BCR-ABL1 RNA International Scale Calibrators and laboratory software reporting tools, intended to aid laboratories with standardization of BCR-ABL1 RT-qPCR testing to the International Scale. As part of this agreement, Asuragen will develop and, if successful, distribute the ARQ BCR-ABL1 IS RNA Calibrators and software reporting tools to laboratories globally directly or through its distributors.

6 Dec 2010

Research findings could provide breakthrough for development of effective therapies for NSCLC

Research at Virginia Commonwealth University Massey Cancer Center led by Charles E. Chalfant, Ph.D., associate professor of biochemistry and molecular Biology, discovered a previously unknown mechanism in non-small cell lung cancer cells that contributes to their ability to maintain and grow tumors. Narrowing in on this mechanism could provide a breakthrough for the development of effective therapies for NSCLC and other cancers.

4 Dec 2010

Research on ribosome could aid antibiotic development against MRSA infection

Theoretical biologists at Los Alamos National Laboratory have used a New Mexico supercomputer to aid an international research team in untangling another mystery related to ribosomes-those enigmatic jumbles of molecules that are the protein factories of living cells.

3 Dec 2010

EPO upholds Alnylam's Tuschl II 1407044 patent

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that the European Patent Office (EPO) has fully upheld its Tuschl II '044 (EP 1407044) patent in oral opposition proceedings held in Munich. Specifically, the originally granted claims of the '044 patent were upheld without any modification and were deemed valid and supported by the EPO.

3 Dec 2010

Sirnaomics cemented partnership with Chinese pharmaceutical to develop siRNA therapeutics

Sirnaomics, Inc. announced today that the company has cemented a partnership with a Chinese pharmaceutical company for development of its small interfering RNA (siRNA) therapeutic (STP705) for scarless wound healing.

3 Dec 2010

MicroRNA linked to mosquito blood digestion and egg development identified

Each year, dengue fever infects as many as 100 million people while yellow fever is responsible for about 30,000 deaths worldwide. Both diseases are spread by infected female Aedes aegypti mosquitoes, which require vertebrate blood to produce eggs. The blood feeding and the egg development are tightly linked to how the mosquito transmits the disease-causing virus.

2 Dec 2010

Mount Sinai’s instructor receives Liz Tilberis Grant from OCRF

AnaLisa DiFeo, PhD, Instructor in the Department of Genetics and Genomic Sciences at Mount Sinai School of Medicine, has been honored by the Ovarian Cancer Research Fund (OCRF) with the Liz Tilberis Grant.

2 Dec 2010

FDA grants 510(k) clearance to Focus Diagnostics Simplexa Flu A/B & RSV test on 3M Integrated Cycler

Quest Diagnostics Incorporated, the world's leading provider of diagnostic testing, information and services, today announced that the U.S. Food and Drug Administration (FDA) has issued 510(k) clearance to the Focus Diagnostics Simplexa Flu A/B & RSV test on the 3M™ Integrated Cycler. The Simplexa test, developed and manufactured by Quest Diagnostics' Focus Diagnostics business, is intended as an aid in the detection and discrimination of influenza A, influenza B and RSV virus infections.

From Quest Diagnostics 2 Dec 2010

LMO1 gene variation can increase neuroblastoma risk

Pediatric cancer researchers have identified variations in a gene as important contributors to neuroblastoma, the most common solid cancer of early childhood. The study team, led by researchers at The Children's Hospital of Philadelphia, found that common variants in the LMO1 gene increase the risk of developing an aggressive form of neuroblastoma, and also mark the gene for continuing to drive the cancer's progression once it forms.

2 Dec 2010

Diabetes plays a vital role in regulating brain cholesterol: Research

The brain contains more cholesterol than any other organ in the body, has to produce its own cholesterol and won't function normally if it doesn't churn out enough. Defects in cholesterol metabolism have been linked with Alzheimer's disease and other neurodegenerative conditions. Now researchers at Joslin Diabetes Center have discovered that diabetes can affect how much cholesterol the brain can make.

1 Dec 2010

Researchers reveal ultra-fast processes of DNA photostability

The genetic material of DNA contains shielding mechanisms to protect itself from the exposure to the UV light emitted by the sun. This is of crucial importance, since without photostability i.e. without programmed defense mechanisms against UV irradiation a rapid degradation of DNA and RNA would be the consequence. As part of a project funded by the Austrian Science Fund (FWF) a group of researchers led by Hans Lischka, Quantum Chemist of the University of Vienna, Austria, could, for the first time, comprehensively unravel these ultra-fast processes of the photostability of the nucleobases.

30 Nov 2010

Argos commences dosing in Arcelis personalized immunotherapy Phase 2b clinical trial for HIV

Argos Therapeutics today announced that it has initiated dosing of patients in a Phase 2b clinical trial of its Arcelis™ personalized immunotherapy for the treatment of HIV patients, AGS-004.

30 Nov 2010

miRagen and t2cure enter licensing agreement for microRNA 92 technology

miRagen Therapeutics, Inc., a biopharmaceutical company focused on improving patients' lives by developing innovative microRNA (miRNA)-based therapeutics for cardiovascular and muscle disease, and t2cure, a clinical stage biopharmaceutical company developing progenitor cell-based regenerative therapeutics for cardiac or peripheral vascular diseases, announced today that they have entered into a licensing agreement

30 Nov 2010

Pharmasset commences combination study of PSI-7977 and PSI-938 nucleotide analogs in HCV

Pharmasset, Inc. announced today that dosing has begun in Part 2 of a Phase 1 study. This is the first clinical study combining a purine (PSI-938) and a pyrimidine (PSI-7977) nucleotide analog for HCV, and is designed to evaluate once daily doses of PSI-7977 and PSI-938 in patients with HCV who have not been treated previously.

30 Nov 2010

NIAID scientists confirm antiviral activity of two lead compounds against HPV

Tamir Biotechnology, Inc. announced today that scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID) reported test results confirming two of our lead compounds showed excellent in vitro antiviral activity and no cellular toxicity at dose levels tested for Human Papillomavirus (HPV).

30 Nov 2010

Overexpression of microRNA 125b can cause leukemia: Research

Whitehead Institute researchers have shown in mouse models that overexpression of the microRNA 125b (miR-125b) can independently cause leukemia and accelerate the disease's progression. Their results are published in this week's online edition of the Proceedings of the National Academy of Sciences (PNAS).

30 Nov 2010

Gen-Probe submits PMA to FDA for APTIMA HPV assay to detect cervical cancer

Gen-Probe Incorporated announced today that the Company has submitted a Premarket Approval Application (PMA) to the US Food and Drug Administration (FDA) for its APTIMA® HPV (human papillomavirus) assay, a new molecular test that detects high-risk HPV infections that are associated with cervical cancer and precancerous lesions.

30 Nov 2010

Transgenomic signs definitive agreement to acquire diagnostic business of Clinical Data

Transgenomic, Inc. announced today the signing of a definitive agreement for Transgenomic to acquire the diagnostic business of Clinical Data, Inc. This acquisition includes a suite of proprietary genetic commercial tests, certain proprietary biomarker assays, and the CLIA-certified laboratory operations of Clinical Data for a purchase price of approximately $15.4 million, primarily in cash and notes.

29 Nov 2010

RNA News and Research

Further Reading

Achillion Pharmaceuticals to present clinical study data of ACH-1625 at APASL 2011

Exiqon announces launch of 6th generation of miRCURY LNA microRNA Arrays

Asuragen, Novartis to develop ARQ BCR-ABL1 RNA IS Calibrators, laboratory software reporting tools

Research findings could provide breakthrough for development of effective therapies for NSCLC

Research on ribosome could aid antibiotic development against MRSA infection

EPO upholds Alnylam's Tuschl II 1407044 patent

Sirnaomics cemented partnership with Chinese pharmaceutical to develop siRNA therapeutics

MicroRNA linked to mosquito blood digestion and egg development identified

Mount Sinai’s instructor receives Liz Tilberis Grant from OCRF

FDA grants 510(k) clearance to Focus Diagnostics Simplexa Flu A/B & RSV test on 3M Integrated Cycler

LMO1 gene variation can increase neuroblastoma risk

Diabetes plays a vital role in regulating brain cholesterol: Research

Researchers reveal ultra-fast processes of DNA photostability

Argos commences dosing in Arcelis personalized immunotherapy Phase 2b clinical trial for HIV

miRagen and t2cure enter licensing agreement for microRNA 92 technology

Pharmasset commences combination study of PSI-7977 and PSI-938 nucleotide analogs in HCV

NIAID scientists confirm antiviral activity of two lead compounds against HPV

Overexpression of microRNA 125b can cause leukemia: Research

Gen-Probe submits PMA to FDA for APTIMA HPV assay to detect cervical cancer

Transgenomic signs definitive agreement to acquire diagnostic business of Clinical Data

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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