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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Scientist develops way to deliver promising genetic tool into living cells

By exploiting an HIV protein that readily traverses cell membranes, Carnegie Mellon University scientists have developed a new way to introduce a gene-like molecule called a peptide nucleic acid (PNA) directly into live mammalian cells, including human embryonic stem (ES) cells.

6 Dec 2004

Next-generation therapeutics with the potential to successfully treat Lou Gehrig's disease

The hopes of many that ALS (commonly referred to as Lou Gehrig's disease) will one day be a disease of the past, studied in medical textbooks, conquered by the dedication of those who have worked tirelessly to eradicate it might be realized in our lifetime.

6 Dec 2004

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Modern research is delving deep into the human genome to find the answers to medical mysteries and, hopefully, cures for the most deadly diseases. According to four new studies presented during the 46th Annual Meeting of the American Society of Hematology

5 Dec 2004

Temperature sensing protein implicated in mediating thermotaxis

The songwriter Noel Coward once declared that only mad dogs and Englishmen went out in the midday sun. MIT biologists Mark Rosenzweig, Paul Garrity and their colleagues now have a third candidate for the lyric—fruit flies with defects in a gene called dTrpA1.

4 Dec 2004

Gene decoding revealed at atomic level

A recent finding by a North Carolina State University biochemist advances the fundamental biology of how genetic information, encoded in DNA, is decoded for the production of proteins.

4 Dec 2004

Viral Genetics announces effects of VGV-1 in antiretroviral non-responding HIV infections

Viral Genetics announced today that the results of a clinical trial of its investigational therapy for HIV infection, VGV-1, were recently published in a peer reviewed journal, HIV & AIDS Review.

29 Nov 2004

Research opens up new avenues to diagnosis and treat Lyme disease

Researchers at Yale School of Medicine have identified a Lyme disease receptor called TROSPA that is used by disease agents to invade ticks.

14 Nov 2004

Research aims to understand how genetic information translates into biological activity

The National Institute of Standards and Technology (NIST) has launched a new $6.25 million, five-year program to explore and address challenges in measurement, validation and quality control for the rapidly growing field of gene expression profiling.

11 Nov 2004

Crystal structure of protein AIRs kinase uncovered

Cornell University researchers, who are trying to understand how proteins evolve and function by looking at their structural features, have uncovered the crystal structure of a protein involved in making the building blocks of DNA correctly.

4 Nov 2004

Gene silencing may provide hope for leukemia sufferers

Ever since the approval of Gleevec in 2001, a cancer-cell-specific drug used to treat chronic myelogenous leukemia (CML), the field of cancer therapeutics has been rushing full speed into the era of so-called "targeted" medicines.

1 Nov 2004

Cellular enzyme represents a potential new target for developing improved HIV drugs

Scientists have discovered that a cellular enzyme helps ferry HIV genetic instructions out of the cell nucleus where they can then be translated into proteins to begin their most destructive work.

1 Nov 2004

New role for a key protein involved in muscle contraction

Overturning a scientific stereotype, researchers at the University of Illinois at Chicago have discovered a new role for a key protein involved in muscle contraction and shown it is present not just in the cytoplasm of cells but in the nucleus as well.

1 Nov 2004

Routine screening of blood samples would reduce the risk of disease transmission among transplant recipients

Results of a study in this week’s issue of THE LANCET suggest that routine screening of blood samples to detect viral RNA among organ and tissue donors who do not have obvious signs of clinical disease would reduce the risk of disease transmission among transplant recipients.

29 Oct 2004

Micro-array technology is revolutionising current drug development

Gene expression micro-array technology is benefiting all phases of the discovery, development and subsequent use of new cancer therapeutics

29 Oct 2004

Study could lead to new, more effective treatments for urinary tract infections

Anyone who thinks scientists lead a glamorous, exciting life should talk to Jennifer Snyder, a graduate student at the University of Maryland’s School of Medicine.

25 Oct 2004

A single change in a person’s DNA can contribute to a range of life-shortening risk factors

A woman with hypertension, low magnesium levels, and a cooperative family allowed scientists to pinpoint the mutation, which affects the genes of the mitochondria — the energy-producing power plants of the cell that are passed from mother to offspring.

25 Oct 2004

Blocking gene opens avenues for treating prostate cancer

Cancer Research UK scientists in Oxford have found a new way to make prostate cancer succumb more readily to currently used treatments.

22 Oct 2004

Detecting diseases with no more to work with than a drop of blood

The dream of monitoring a patient's physical condition through blood testing has long been realized. But how about detecting diseases in their very early stages, or evaluating how they are responding to treatment, with no more to work with than a drop of blood!

22 Oct 2004

Researchers have developed a novel drug-antidote pair

In a discovery that could give physicians more control over the actions of medications, researchers at Duke University Medical Center have developed a novel drug pair – a potent anti-coagulant with a matched "antidote."

18 Oct 2004

Researchers have identified a protein in the inner ear that translates sound into the nerve impulses used by the brain

Researchers at Harvard Medical School and their colleagues report in the October 13 Nature advanced on-line edition that they have identified a protein deep in the inner ear that they believe translates sound into the nerve impulses used by the brain.

13 Oct 2004

RNA News and Research

Further Reading

Scientist develops way to deliver promising genetic tool into living cells

Next-generation therapeutics with the potential to successfully treat Lou Gehrig's disease

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Temperature sensing protein implicated in mediating thermotaxis

Gene decoding revealed at atomic level

Viral Genetics announces effects of VGV-1 in antiretroviral non-responding HIV infections

Research opens up new avenues to diagnosis and treat Lyme disease

Research aims to understand how genetic information translates into biological activity

Crystal structure of protein AIRs kinase uncovered

Gene silencing may provide hope for leukemia sufferers

Cellular enzyme represents a potential new target for developing improved HIV drugs

New role for a key protein involved in muscle contraction

Routine screening of blood samples would reduce the risk of disease transmission among transplant recipients

Micro-array technology is revolutionising current drug development

Study could lead to new, more effective treatments for urinary tract infections

A single change in a person’s DNA can contribute to a range of life-shortening risk factors

Blocking gene opens avenues for treating prostate cancer

Detecting diseases with no more to work with than a drop of blood

Researchers have developed a novel drug-antidote pair

Researchers have identified a protein in the inner ear that translates sound into the nerve impulses used by the brain

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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