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New pan-cancer T cell atlas provides a deeper understanding of complex tumor microenvironment

A new study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, provides a deeper understanding of the vast diversity of T cell states as well as their relationships and roles within the complex tumor microenvironment, bringing a fresh perspective to understanding immunotherapy efficacy in cancer.

29 May 2023

First systematic single-cell analysis of transcriptional variation within the T cell population

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Immune cells play important roles in mediating allograft rejection and tolerance after cardiac transplantation.

25 May 2023

Study examines the role of genetic variants across diverse ancestries in regulating gene expression

Exploring diverse ancestry is a critical factor in furthering medical research.

25 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

Identify the underlying mechanism associated with the initiation of focal amplification in breast cancer

Identifying the underlying mechanism associated with the initiation of focal amplification in breast cancer.

19 May 2023

MSU researchers create the first annotated Montmorency tart cherry genome

Since Michigan is the nation's leading producer of tart cherries, Michigan State University researchers were searching for the genes associated with tart cherry trees that bloom later in the season to meet the needs of a changing climate.

18 May 2023

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

The gene ECHS1 encodes for enoyl-CoA hydratase short-chain 1, a mitochondrial enzyme involved in branched-chain amino acid and fatty acid metabolism.

18 May 2023

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers at Children's Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

17 May 2023

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

A pair of internationally renowned stem cell cloning experts at the University of Houston is reporting their findings of variant cells in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF) which likely represent key targets in any future therapy for the condition.

17 May 2023

Democratizing RNA sequencing: A breakthrough in cost and efficiency

CSEM has supported the Lausanne-based start-up Alithea Genomics in developing a technology capable of processing hundreds of ribonucleic acid (RNA) samples in a single tube, which translates to a significant reduction in reagents and manual effort in the overall workflow.

From CSEM 17 May 2023

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Researchers conducted a phase I clinical trial of a personalized mRNA neoantigen vaccine.

12 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

A new study investigates whether SARS-CoV-2 can enter and replicate in macrophages and whether ACE2 is involved in these mechanisms.

4 May 2023

The Evolution of Molecular Biology

In this interview, Istvan Szatmari, the Head of The Genomic Core Facility at the Department of Biochemistry and Molecular Biology, talks to NewsMed about the evolution of Molecular Biology.

From MGI 4 May 2023

How the COVID pandemic has improved genomics

In this interview, Davide Cacchiarelli, Molecular Biology and Genomics Professor at the University of Naples talks to NewsMed about how the COVID pandemic has highlighted the vital role of genomic surveillance and improved genomics.

From MGI 4 May 2023

MGI Announces New Customer Experience Center in South Korea with BMS

Cheonan, South Korea, 26 April 2023 – MGI Tech Co. Ltd. (MGI), a company committed to building core tools and technology to lead life science, today celebrated the opening of its Customer Experience Center (CEC) in South Korea. In partnership with one of the country’s leading companies in life science technology, BMS (Bio-Medical science Co., Ltd.), the new CEC based in Cheonan aims to provide local customers and partners with the first-hand access to MGI's cutting-edge products.

From MGI 27 Apr 2023

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer's disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists.

24 Apr 2023

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.