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Good news for people with glycogen storage disease type Ia

A gene therapy treatment that restores a missing liver enzyme in test animals could provide a cure for a rare metabolic disorder in humans, according to Duke University Medical Center researchers.

13 Mar 2008

Guidelines for von Willebrand disease diagnosis and management

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health today issued the first clinical guidelines in the United States for the diagnosis and management of von Willebrand Disease (VWD), the most common inherited bleeding disorder.

4 Mar 2008

Adult stem cell changes underlie Hutchinson-Gilford Progeria syndrome associated with accelerated aging

Adult stem cells may provide an explanation for the cause of a Hutchinson-Gilford Progeria Syndrome (HGPS), a rare disease that causes premature aging in children, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

3 Mar 2008

NIDDK releases new awareness series on diabetes, digestive diseases and kidney and urologic diseases

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has announced the release of new health information to raise awareness about diabetes, digestive diseases, and kidney and urologic diseases among people not yet diagnosed with these illnesses.

1 Mar 2008

New online information resource on bladder problems

Women with bladder control problems can learn about treatments and techniques to help them manage their condition in a new resource from the National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC), an information dissemination service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), one of the National Institutes of Health (NIH).

1 Mar 2008

Hydroxyurea for sickle cell patients

An independent panel convened this week by the NIH concluded that the use of hydroxyurea for sickle cell patients should be increased in adolescents and adults.

28 Feb 2008

New NIH cholesterol website for seniors

Many older adults have their blood cholesterol level checked regularly.

28 Feb 2008

NCMHD announces HIV/AIDS expert as new senior policy advisor

Idalia Ramos Sanchez, a longtime fighter for health equity especially as it relates to HIV/AIDS, has been appointed senior policy advisor at the National Center on Minority Health and Health Disparities (NCMHD), National Institutes of Health (NIH).

27 Feb 2008

Cognitive impairment among older Americans is declining

Rates of cognitive impairment among older Americans are on the decline, according to a new study supported by the National Institutes of Health (NIH) comparing the cognitive health of older people in 1993 and 2002.

27 Feb 2008

Smoking's effects on genes may play a role in lung cancer development and survival

Smoking plays a role in lung cancer development, and now scientists have shown that smoking also affects the way genes are expressed, leading to alterations in cell division and regulation of immune response.

21 Feb 2008

Discovery of antibody that neutralizes two viruses classified as henipaviruses

In laboratory experiments, scientists at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), and their colleagues supported by the NIH National Institute of Allergy and Infectious Disease (NIAID), have discovered an antibody that neutralizes two viruses classified as henipaviruses.

18 Feb 2008

Cholesterol-lowering drug used to block staph infections in mince

An international team of researchers supported by the National Institutes of Health (NIH) has blocked staph infections in mice using a drug previously tested in clinical trials as a cholesterol-lowering agent.

17 Feb 2008

NIH and EPA announce new chemical toxicity testing agreement

Testing the safety of chemicals ranging from pesticides to household cleaners will benefit from new technologies and a plan for collaboration, according to federal scientists from the National Institutes of Health (NIH) and the U.S. Environmental Protection Agency (EPA), who today announced a new toxicity testing agreement.

17 Feb 2008

For safety, NHLBI changes intensive blood sugar treatment strategy in trial of diabetes and cardiovascular disease

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped one treatment within a large, ongoing North American clinical trial of diabetes and cardiovascular disease 18 months early due to safety concerns after review of available data, although the study will continue.

6 Feb 2008

Discovery of novel molecular pattern linked to colon cancer prognosis

An international research team has identified a link between the expression patterns of a class of molecules called microRNAs and how a patient's colon cancer may progress.

29 Jan 2008

Bisphosphonates - osteoporosis drugs triple risk of bone necrosis

A University of British Columbia and Vancouver Coastal Health Research Institute study has found that a popular class of osteoporosis drugs nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain.

16 Jan 2008

New genetic variations associated with lipid levels, risk for coronary artery disease

Environmental and genetic factors influence a person's blood fat, or lipid levels, important risk factors for coronary artery disease (CAD). While there is some understanding of the environmental contribution, the role of genetics has been less defined.

14 Jan 2008

Study suggests link between genetic basis of height and arthritis

In studies involving more than 35,000 people and a survey across the entire human genome, an international team supported in part by the National Institutes of Health (NIH) has found evidence that common genetic variants recently linked to osteoarthritis may also play a minor role in human height.

14 Jan 2008

New biomarker for predicting liver cancer spread and survival discovered

New research has shown that a unique pattern of microRNAs, small RNA molecules that regulate gene activity, can accurately predict whether liver cancer will spread and whether liver cancer patients will have shorter or longer survival, even patients with early stage disease.

7 Jan 2008

NIEHS awards $6.8 million DISCOVER grants

The National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, is awarding a total of $6.8 million for the first year of funding to three new research centers called DISCOVER - Disease Investigation Through Specialized Clinically-Oriented Ventures in Environmental Research.

28 Dec 2007