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UAB researchers create small molecule that prevents tooth cavities in preclinical model

University of Alabama at Birmingham researchers have created a small molecule that prevents or impedes tooth cavities in a preclinical model.

10 Aug 2017

Scientists develop new surgical method to reconnect sensory neurons with spinal cord after injury

Scientists in the UK and Sweden previously developed a new surgical technique to reconnect sensory neurons to the spinal cord after traumatic spinal injuries.

28 Jul 2017

Research may lead to treatment for long-term sensory problems in cardiac arrest survivors

Research conducted by Jason Middleton, PhD, Assistant Professor of Cell Biology and Anatomy, and Neuroscience at LSU Health New Orleans School of Medicine, and colleagues may lead to a treatment to prevent long-term sensory problems by restoring normal brain function in survivors of cardiac arrest.

24 Jul 2017

Novel approach could offer hope in treatment of inflammatory conditions

The team, led by researchers at Imperial College London, Queen Mary University of London and Ergon Pharmaceuticals, believes the approach could offer new hope in the treatment of inflammatory conditions like arthritis, autoimmune diseases, and sepsis.

12 Jul 2017

Fetal alcohol exposure reduces taste system's responsiveness to bitter flavor and burning sensation

A new study suggests that fetal alcohol exposure reduces the taste system's responsiveness to the bitter flavor and burning sensation of many varieties of alcoholic beverages.

18 May 2017

Hair-derived keratin biomaterials show promise to regenerate skeletal muscle tissue and function

The use of human hair-derived keratin biomaterials to regenerate skeletal muscle has shown promise in new research that documents significant increases in both new muscle tissue formation and muscle function among mouse models of volumetric muscle loss.

27 Apr 2017

Rat study reveals new clues to devastating neurological disease

After a 29-year quest, Ian Duncan, a professor of veterinary medicine at the University of Wisconsin-Madison, has finally pinpointed the cause of a serious neurologic disease in a colony of rats.

20 Apr 2017

Could light from LED screens cause irreversible eye damage?

The study carried out by the Complutense University of Madrid (Spain) –UCM – is the first to evaluate retinal damage using tablets with LED screens available in the market with living animals.

30 Mar 2017

Heroin use linked to epigenetic alterations in the brain

Heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression, and more years of drug use correlate with higher levels of hyperacetylation, according to research conducted at The Icahn School of Medicine at Mount Sinai and published in the journal Biological Psychiatry.

22 Mar 2017

Heroin use linked to epigenetic alterations in the brain

The past few years have seen an explosion of heroin abuse and deaths from opiate overdose. But little is known about the molecular underpinnings of heroin addiction.

14 Mar 2017

Research shines new light on role of AKI in development of lung injury

Acute kidney injury (AKI) is sudden kidney failure or damage lasting from a few hours to several days. During this time, the kidney's ability to maintain a proper balance of bodily fluids is compromised and causes a buildup of waste products in the blood.

22 Feb 2017

Scientists gain better understanding of how depression could affect thinking

Depression is associated with sadness, fatigue and a lack of motivation. But people with depression can also have trouble processing information and solving problems.

15 Feb 2017

TSRI scientists describe how key molecules in the brain work together to trigger intense anxiety

In a new study, researchers at The Scripps Research Institute have described how two important molecules in the brain work together to trigger intense anxiety.

13 Feb 2017

Researcher finds new ways to adapt corn protein-based drug delivery method to pediatric medications

Developing medications for children can be challenging—taste and texture are important, but safety is also a major concern, according to pharmaceutical sciences professor Om Perumal at South Dakota State University.

13 Feb 2017

Increased growth factor protects retinal blood vessels in animal models with diabetes

Researchers from the Schepens Eye Research Institute of Massachusetts Eye and Ear have shown that a slight increase in transforming growth factor beta (TGF-β), which is present in preclinical animal models with diabetic eye disease, protects retinal blood vessels from damage that commonly occurs in the early stages of the disease.

2 Feb 2017

Researchers reveal how soy consumption impacts common breast cancer treatment

Georgetown Lombardi Comprehensive Cancer Center researchers have used animal models to reveal new information about the impact - positive and negative - that soy consumption could have on a common breast cancer treatment.

1 Feb 2017

Review discusses how neglect of sex differences in obesity research can affect treatment in females

One of the environmental factors that promote obesity, and the consequent health problems, are energy dense diets.

31 Jan 2017

Mount Sinai study characterizes genetically modified rat model of autism and intellectual disability

Researchers at The Seaver Autism Center for Research and Treatment at Mount Sinai have generated and characterized a genetically modified rat model of autism and intellectual disability, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published January 31 in the journal eLife.

31 Jan 2017

Researchers evaluate use of regenerative human umbilical cord for in-utero spina bifida repair

In a study to be presented Saturday, Jan. 28, in the oral concurrent session at 8:45 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers evaluated a possible regenerative patch by using human umbilical cord in two studies titled Cryopreserved Human Umbilical Cord (HUC) vs Acellular Dermal Matrix (ADM) for In-Utero Spina Bifida Repair and the study Conventional vs cryopreserved human umbilical cord (HUC) patch based on repair for in-utero spina bifida in a sheep model.

23 Jan 2017

Blue maize may help protect against metabolic syndrome, rat study shows

A new study shows that a rat model of metabolic syndrome fed a high-sugar and high-cholesterol diet and given blue maize extract showed significant improvement in systolic blood pressure, high density lipoprotein (HDL) cholesterol, and triglyceride levels compared to those not given the extract.

11 Jan 2017

Rat Model News and Research

UAB researchers create small molecule that prevents tooth cavities in preclinical model

Scientists develop new surgical method to reconnect sensory neurons with spinal cord after injury

Research may lead to treatment for long-term sensory problems in cardiac arrest survivors

Novel approach could offer hope in treatment of inflammatory conditions

Fetal alcohol exposure reduces taste system's responsiveness to bitter flavor and burning sensation

Hair-derived keratin biomaterials show promise to regenerate skeletal muscle tissue and function

Rat study reveals new clues to devastating neurological disease

Could light from LED screens cause irreversible eye damage?

Heroin use linked to epigenetic alterations in the brain

Heroin use linked to epigenetic alterations in the brain

Research shines new light on role of AKI in development of lung injury

Scientists gain better understanding of how depression could affect thinking

TSRI scientists describe how key molecules in the brain work together to trigger intense anxiety

Researcher finds new ways to adapt corn protein-based drug delivery method to pediatric medications

Increased growth factor protects retinal blood vessels in animal models with diabetes

Researchers reveal how soy consumption impacts common breast cancer treatment

Review discusses how neglect of sex differences in obesity research can affect treatment in females

Mount Sinai study characterizes genetically modified rat model of autism and intellectual disability

Researchers evaluate use of regenerative human umbilical cord for in-utero spina bifida repair

Blue maize may help protect against metabolic syndrome, rat study shows

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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