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Moderate exercise may help treat memory impairment in patients with type 2 diabetes

University of Tsukuba-led researchers show that moderate exercise may improve hippocampal memory dysfunction caused by type 2 diabetes and that enhanced transport of lactate to neurons may be the underlying mechanism

9 Dec 2016

Cigarette smoking may lead to fibrosis in the heart and kidneys, study reveals

Smoking may lead to fibrosis in the heart and kidneys and can worsen existing kidney disease, according to a new study.

1 Dec 2016

Long-term hormone treatment may negatively affect kidneys in postmenopausal women

Long-term estrogen treatment after menopause may increase the risk of new kidney damage and negatively affect women with abnormal kidney function.

29 Nov 2016

Improved skin graft process shows promise for treating severe burn wounds

Full thickness skin grafts are the golden standard for treating burn wounds. But most skin grafts for severe burns require a donor, and for large or complicated injury sites, a full thickness skin graft is hard to come by.

31 Oct 2016

Folinic acid treatment could help improve language and communication skills of children with ASD

Prescription doses of folinic acid, which is a reduced form of a B vitamin known as folate, could help improve the language and communication skills of children with autism spectrum disorder (ASD).

18 Oct 2016

Early-life soy protein diet may protect against serious bone loss during adulthood

Move over milk, soy protein early in life might be what's needed for strong, healthy bones in adulthood.

17 Oct 2016

Research shows how mitochondrial targeting antioxidants could help treat osteoarthritis

High cholesterol might harm more than our cardiovascular systems. New research using animal models, published online in The FASEB Journal, suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis.

17 Oct 2016

Study finds decreased cysteine/cystine ratio could serve as accurate redox biomarker for epilepsy

Approximately 2.9 million people in the United States suffer from epilepsy, according to the CDC.

5 Oct 2016

Early-life infections may be risk factor for developmental disorders later in life

The Zika virus now active in numerous countries, and the severe birth defects associated with it, makes it clear that infection in pregnant women can have immediate and devastating effects on the developing baby.

19 Aug 2016

Gut microbiota could influence person's likelihood of developing colon cancer

The microscopic organisms that live in our gut do more than help us digest food. A new study in rats bolsters a growing body of evidence that the complex mix of microorganisms found in the gut, known as gut microbiota, could influence a person's likelihood of developing colon cancer.

13 Jul 2016

Single dose of new molecule could protect the brain from cognitive impairments after mTBI

A new molecule could protect the brain from cognitive impairments after a mild traumatic brain injury, according to Hebrew University of Jerusalem scientists.

11 Jul 2016

Aerobic exercise training reestablishes cardiac protein quality control system in heart failure rats

Aerobic exercise training restored the cardiac protein quality control system in rats showed a study recently published in Journal of Cellular and Molecular Medicine.

8 Jul 2016

Low birth weight, stress during pregnancy can lead to long-term health issues in women

Low birth weight or stress during pregnancy can lead to long-term health problems in women, according to a study published today in The Journal of Physiology.

13 Jun 2016

Tackling healthcare challenges in a changing world: an interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that tiny particles made of a biodegradable polymer (BNPs -- biodegradable polymer nanoparticles) have the potential to enable early detection and efficient long-term treatment of rheumatoid arthritis (RA), with minimal side effects.

10 Jun 2016

Researchers investigate causes of renal failure using mathematical model

No one can deny that open-heart surgery, where the heart is exposed and the blood is made to bypass it, is one of the most invasive of all medical procedures. Nearly a third of all patients undergoing heart surgery experience kidney failure, yet little is known about why kidney injury occurs or how to prevent it.

9 Jun 2016

Researchers detect vascular matrix stiffening during early stages of pulmonary hypertension

Pulmonary hypertension is an abnormal elevation of pressure in the pulmonary circulation that results in stress on the heart and remodeling of blood vessels in the lung.

3 Jun 2016

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Using gene editing technology, researchers at the Lewis Katz School of Medicine at Temple University have, for the first time, successfully excised a segment of HIV-1 DNA - the virus responsible for AIDS - from the genomes of living animals.

20 May 2016

Estrogen-inhibiting drug may suppress dangerous brain seizures

A class of drug that inhibits estrogen production and is used to treat breast cancer has been found to quickly and effectively suppress dangerous brain seizures, according to a new Northwestern University study.

13 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016