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Scientists at NIH and Emory University induce sustained remission in SIV-infected monkeys

Scientists at the National Institutes of Health and Emory University have experimentally induced sustained remission of SIV, the simian form of HIV, in infected monkeys.

14 Oct 2016

Depriving deadly brain cancer cells of cholesterol causes tumor regression in mouse models

Researchers at University of California San Diego School of Medicine, Ludwig Institute for Cancer Research and The Scripps Research Institute, with colleagues in Los Angeles and Japan, report that depriving deadly brain cancer cells of cholesterol, which they import from neighboring healthy cells, specifically kills tumor cells and caused tumor regression and prolonged survival in mouse models.

13 Oct 2016

Scientists develop smart drug that safely removes fat from liver and blood vessels

Scientists from the Technical University of Munich and Helmholtz Zentrum München have developed a ‘smart’ drug that safely clears the liver of fat and prevents blood vessels from clogging up.

13 Oct 2016

Study identifies mechanistic link between maternal obesity and childhood hypertension

Exposure of babies to high levels of the 'fullness' hormone, leptin, in the womb irreversibly activates receptors in the brain that regulate blood pressure, according to a new study by researchers from King's College London, part-funded by the British Heart Foundation.

12 Oct 2016

Research findings provide new avenues to target virus infection

Viral infection is one of the leading medical challenges of the 21st Century, ranging from the Hepatitis C Virus (HCV) epidemic affecting 3% of the global population, to recent outbreaks of West Nile, Zika, and Ebola viruses.

12 Oct 2016

Research on naked mole-rats could pave way for new human pain therapies

In injuries and inflammation, naked mole-rats do not develop normal hypersensitivity to temperature stimuli.

12 Oct 2016

Study to examine efficacy of orally administered medication in treating stuttering

Stuttering, an interruption in the flow of speech, affects about three million Americans. It begins most often in childhood, affecting four men for every woman. A precise cause of this complex communicative disorder is not known.

8 Oct 2016

Researchers describe novel host-oriented therapeutic approach for preventing lethal immune responses

Staphylococcal and streptococcal infections affect millions of individuals each year. They are a leading cause of sepsis and account for many cases of pneumonia and post-surgical infections.

8 Oct 2016

Estrogen receptor degrader increases progression-free survival in advanced breast cancer patients

Fulvestrant significantly increases progression-free survival in women with hormone-receptor-positive advanced breast cancer, particularly those with less aggressive lower-volume disease, researchers reported at the ESMO 2016 Congress in Copenhagen

8 Oct 2016

Combination treatment with CDK4/6 inhibitor improves progression-free survival in HR+ breast cancer patients

The addition of the CDK4/6 inhibitor ribociclib to letrozole therapy significantly improves progression-free survival in postmenopausal women with hormone receptor-positive advanced breast cancer, researchers reported today at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

Study of pan-FGFR inhibitor uses mRNA in tumours to identify responders

The first-in-human dose escalation study of the pan-FGFR (fibroblast growth factor receptor) inhibitor BAY 1163877 in patients with treatment-refractory locally advanced or metastatic solid tumours were reported today at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

Research reveals role of endoglin in shaping blood and cardiac cell fate during early development

New research from the University of Minnesota reveals endoglin as a critical factor in determining the fate of early undifferentiated cells during development.

7 Oct 2016

Researchers explain why explain why some tumors recur after immunotherapy

Immunotherapy is a new and highly promising form of treatment for cancer. In many patients, however, tumors recur after immunotherapy.

7 Oct 2016

No added benefit proven for pulmonary arterial hypertension drug, IQWiG finds

Selexipag is approved for long-term treatment of pulmonary arterial hypertension (PAH) in adults with moderate to severe symptoms.

7 Oct 2016

TUM scientists shed new light on metastases in the liver at early stage of pancreatic cancer

Pancreatic cancer is an exceptionally aggressive type of cancer. Frequently, metastases already start to grow in other organs, particularly often in the liver, before the original tumor was even detected.

7 Oct 2016

Study finds neoadjuvant immunotherapy safe, viable for early lung cancer patients before surgery

Neoadjuvant immunotherapy with the PD-1 inhibitor nivolumab is safe and feasible prior to surgery for early lung cancer, researchers reported at the ESMO 2016 Congress in Copenhagen.

7 Oct 2016

BUSM researchers identify new therapeutic target for treating compulsive binge eating

A new therapeutic target for the treatment of compulsive binge eating has been identified by researchers at Boston University School of Medicine.

6 Oct 2016

Researchers identify new strategy to selectively sensitize cancer cells to radiation therapy

Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects.

5 Oct 2016

Fruit flies shed light on how insulin signaling processes may be altered by diabetes in humans

Fruit flies may be small, but the genetic secrets they can unlock for humans are mighty.

4 Oct 2016

Can vitamin D reduce asthma attacks? An interview with Professor Adrian Martineau

In the past vitamin D was just thought to be important in regulating calcium homeostasis and bone health as vitamin D deficiency is best known for causing rickets in children and osteomalacia in adults.

4 Oct 2016

Receptor News and Research

Scientists at NIH and Emory University induce sustained remission in SIV-infected monkeys

Depriving deadly brain cancer cells of cholesterol causes tumor regression in mouse models

Scientists develop smart drug that safely removes fat from liver and blood vessels

Study identifies mechanistic link between maternal obesity and childhood hypertension

Research findings provide new avenues to target virus infection

Research on naked mole-rats could pave way for new human pain therapies

Study to examine efficacy of orally administered medication in treating stuttering

Researchers describe novel host-oriented therapeutic approach for preventing lethal immune responses

Estrogen receptor degrader increases progression-free survival in advanced breast cancer patients

Combination treatment with CDK4/6 inhibitor improves progression-free survival in HR+ breast cancer patients

Study of pan-FGFR inhibitor uses mRNA in tumours to identify responders

Research reveals role of endoglin in shaping blood and cardiac cell fate during early development

Researchers explain why explain why some tumors recur after immunotherapy

No added benefit proven for pulmonary arterial hypertension drug, IQWiG finds

TUM scientists shed new light on metastases in the liver at early stage of pancreatic cancer

Study finds neoadjuvant immunotherapy safe, viable for early lung cancer patients before surgery

BUSM researchers identify new therapeutic target for treating compulsive binge eating

Researchers identify new strategy to selectively sensitize cancer cells to radiation therapy

Fruit flies shed light on how insulin signaling processes may be altered by diabetes in humans

Can vitamin D reduce asthma attacks? An interview with Professor Adrian Martineau

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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